Targeted gene deletion demonstrates that the cell adhesion molecule ICAM-4 is critical for erythroblastic island formation

Blood

Volumn 108, Issue 6, 2006, Pages 2064-2071

  Lee, Gloria ^b   Lo, Annie ^b   Short, Sarah A ^b   Mankelow, Tosti J ^b   Spring, Frances ^b   Parsons, Stephen F ^b   Yazdanbakhsh, Karina ^b   Mohandas, Narla ^b   Anstee, David J ^b   Chasis, Joel Anne ^a  

^a LAWRENCE BERKELEY NATIONAL LABORATORY   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

CD51 ANTIGEN; CELL ADHESION MOLECULE; INTERCELLULAR ADHESION MOLECULE 4; SYNTHETIC PEPTIDE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BONE MARROW; BONE MARROW CELL; COMPARATIVE STUDY; CONTROLLED STUDY; ERYTHROBLAST; ERYTHROPOIESIS; GENE DELETION; IN VITRO STUDY; IN VIVO STUDY; INHIBITION KINETICS; KNOCKOUT MOUSE; LIVER CELL; MACROPHAGE; MOLECULAR BIOLOGY; MOUSE; NONHUMAN; NULL ALLELE; PRIORITY JOURNAL; PROTEIN FUNCTION; QUANTITATIVE ANALYSIS; WILD TYPE;

EID: 33748687965     PISSN: 00064971     EISSN: 00064971     Source Type: Journal    
DOI: 10.1182/blood-2006-03-006759     Document Type: Article

References (44)

1. Allen TD, Dexter TM. Ultrastructural aspects of erythropoietic differentiation in long-term bone marrow culture. Differentiation. 1982;21:86-94.
2. Bessis M. L'ilot erythroblastique. Unite functionelle de la moelle osseuse. Rev Hematol. 1958;13:8-11.
3. Hanspal M, Hanspal J. The association of erythroblasts with macrophages promotes erythroid proliferation and maturation: a 30-kD heparin-binding protein is involved in this contact. Blood. 1994;84:3494-3504.
4. Mohandas N, Prenant M. Three-dimensional model of bone marrow. Blood. 1978;51:633-643.
5. Anstee DJ, Holmes CH, Judson PA, Tanner MJ. Use of monoclonal antibodies to determine the distribution of red cell surface proteins on human cells and tissues. In: Agre PC, Cartron JP eds. Proteins Blood Group Antigens of Human Red Cell: Structure, Function and Clinical Significance. Baltimore, MD: Johns Hopkins University Press; 1992:170-181.
6. Spring FA, Parsons SF, Ortlepp S, et al. Intercellular adhesion molecule-4 binds alpha(4)beta(1) and alpha(V)-family integrins through novel integrin-binding mechanisms. Blood. 2001;98:458-466.
7. Anstee DJ, Mallinson G. The biochemistry of blood group antigens - some recent advances. Vox Sang. 1994;67(suppl 3):1-6.
8. Bailly P, Hermand P, Callebault I, et al. The LW blood group glycoprotein is homologous to intercellular adhesion molecules. Proc Natl Acad Sci U S A. 1994;91:5306-5310.
9. Hermand P, Le Pennec PY, Rouger P, Cartron JP, Bailly P. Characterization of the gene encoding the human LW blood group protein in LW+ and LW- phenotypes. Blood. 1996;87:2962-2967.
10. Southcott MJ, Tanner MJ, Anstee DJ. The expression of human blood group antigens during erythropoiesis in a cell culture system. Blood. 1999;93:4425-4435.
11. Mankelow TJ, Spring FA, Parsons SF, et al. Identification of critical amino-acid residues on the erythroid intercellular adhesion molecule-4 (ICAM-4) mediating adhesion to alpha V integrins. Blood. 2004;103:1503-1508.
12. Lee G, Spring FA, Parsons SF, Mankelow TJ, et al. Novel secreted isoform of adhesion molecule ICAM-4: potential regulator of membrane-associated ICAM-4 interactions. Blood. 2003;101:1790-1797.
13. Paszty C, Mohandas N, Stevens ME, et al. Lethal alpha-thalassaemia created by gene targeting in mice and its genetic rescue. Nat Genet. 1995;11:33-39.
14. Tybulewicz VL, Crawford CE, Jackson PK, Bronson RT, Mulligan RC. Neonatal lethality and lymphopenia in mice with a homozygous disruption of the c-abl proto-oncogene. Cell. 1991;65:1153-1163.
15. Sonneborn HH, Uthemann H, Tills D, Lomas CG, Shaw MA, Tippett P. Monoclonal anti-Lwab. Biotest Bull 2. 1984:145-148.
16. Sasmono RT, Oceandy D, Pollard JW, et al. A macrophage colony-stimulating factor receptor-green fluorescent protein transgene is expressed throughout the mononuclear phagocyte system of the mouse. Blood. 2003;101:1155-1163.
17. Auffray I, Marfatia S, de Jong K, et al. Glycophorin A dimerization and band 3 interaction during erythroid membrane biogenesis: in vivo studies in human glycophorin A transgenic mice. Blood. 2001;97:2872-2878.
18. Austyn JM, Gordon S. F4/80, a monoclonal antibody directed specifically against the mouse macrophage. Eur J Immunol. 1981;11:805-815.
19. Hume DA, Robinson AP, MacPherson GG, Gordon S. The mononuclear phagocyte system of the mouse defined by immunohistochemical localization of antigen F4/80. Relationship between macrophages, Langerhans cells, reticular cells, and dendritic cells in lymphoid and hematopoietic organs. J Exp Med. 1983;158:1522-1536.
20. Bessis M, Mize C, Prenant M. Erythropoiesis: comparison of in vivo and in vitro amplification. Blood Cells. 1978;4:155-174.
21. Le Charpentier Y, Prenant M. [Isolation of erythroblastic islands. Study by optical and scanning electron microscopy (author's transl)]. Nouv Rev Fr Hematol. 1975;15:119-140.
22. Lee SH, Crocker PR, Westaby S, et al. Isolation and immunocytochemical characterization of human bone marrow stromal macrophages in hemopoietic clusters. J Exp Med. 1988;168:1193-1198.
23. Sadahira Y, Mori M. Role of the macrophage in erythropoiesis. Pathol Int. 1999;49:841-848.
24. Yokoyama T, Kitagawa H, Takeuchi T, Tsukahara S, Kannan Y. No apoptotic cell death of erythroid cells of erythroblastic islands in bone marrow of healthy rats. J Vet Med Sci. 2002;64:913-919.
25. Arkin S, Naprstek B, Guarini L, Ferrone S, Lipton J. Expression of intercellular adhesion molecule-1 (CD54) on hematopoietic progenitors. Blood. 1991;77:948-953.
26. Armeanu S, Buhring H-J, Reuss-Borst M, Muller CA, Klein G. E-cadherin is functionally involved in the maturation of the erythroid lineage. J Cell Biol. 1995;131:243-249.
27. El Nemer W, Gane P, Colin Y, et al. The Lutheran blood group glycoproteins, the erythroid receptors for laminin, are adhesion molecules. J Biol Chem. 1998;273:16686-16693.
28. Kansas GS, Muirhead MJ, O'Dailey MO. Expression of the CD11/CD18, leukocyte adhesion molecule 1, and CD44 adhesion molecules during normal myeloid and erythroid differentiation in humans. Blood. 1990;76:2483-2492.
29. Lewinsohn DM, Nagler A, Ginzton N, Greenberg P, Butcher EC. Hematopoietic progenitor cell expression of the H-CAM (CD44) homing-associated adhesion molecule. Blood. 1990;75:589-595.
30. Papayannopoulou T, Brice M. Integrin expression profiles during erythroid differentiation. Blood. 1992;79:1686-1694.
31. b polymorphisms. Blood. 1997;89:4219-4225.
32. Rosemblatt M, Vuilett-Gaugler MH, Leroy C, Coulombel L. Coexpression of two fibronectin receptors, VLA-4 and VLA-5 by immature human erythroblastic precursor cells. J Clin Invest. 1991;87:6-11.
33. Simmons P, Masinovsky B, Longenecker BM, Berenson R, Torok-Storb B, Gallatin WM. Vascular cell adhesion molecule-1 expressed by bone marrow stromal cells mediates the binding of hematopoietic progenitor cells. Blood. 1992;80:388-395.
34. Zen Q, Cottman M, Truskey G, Fraser R, Telen M. Critical factors in basal cell adhesion molecule/Lutheran-mediated adhesion to laminin. J Biol Chem. 1999;274:728-734.
35. Teglund S, McKay C, Schuetz E, et al. Stat5a and Stat5b proteins have essential and nonessential, or redundant, roles in cytokine responses. Cell. 1998;93:841-850.
36. L induction. Cell. 1999;98:181-191.
37. Socolovsky M, Nam H, Fleming MD, Haase VH, Brugnara C, Lodish HF. Ineffective erythropoiesis in Stat5a(-/-)5b(-/-) mice due to decreased survival of early erythroblasts. Blood. 2001;98:3261-3273.
38. Hanspal M, Smockova Y, Uong Q. Molecular identification and functional characterization of a novel protein that mediates the attachment of erythroblasts to macrophages. Blood. 1998;92:2940-2950.
39. Sadahira Y, Yoshino T, Monobe Y. Very late activation antigen 4-vascular cell adhesion molecule 1 interaction is involved in the formation of erythroblastic islands. J Exp Med. 1995;181:411-415.
40. Papayannopoulou T, Priestley GV, Nakamoto B, Zafiropoulos V, Scott LM, Harlan JM. Synergistic mobilization of hemopoietic progenitor cells using concurrent beta1 and beta2 integrin blockade or beta2-deficient mice. Blood. 2001;97:1282-1288.
41. Scott LM, Priestley GV, Papayannopoulou T. Deletion of alpha4 integrins from adult hematopoietic cells reveals roles in homeostasis, regeneration, and homing. Mol Cell Biol. 2003;23:9349-9360.
42. Gutierrez L, Lindeboom F, Langeveld A, Grosveld F, Philipsen S, Whyatt D. Homotypic signalling regulates Gata1 activity in the erythroblastic island. Development. 2004;131:3183-3193.
43. De Maria R, Testa U, Luchetti L, et al. Apoptotic role of Fas/Fas ligand system in the regulation of erythropoiesis. Blood. 1999;93:796-803.
44. Matsushima T, Nakashima M, Oshima K, et al. Receptor binding cancer antigen expressed on SiSo cells, a novel regulator of apoptosis of erythroid progenitor cells. Blood. 2001;98:313-321.