A brave new world in the life sciences

Bulletin of the Atomic Scientists

Volumn 62, Issue 5, 2006, Pages

  Choffnes, Eileen R ^a   Lemon, Stanley M ^a,b   Relman, David A ^c  

^a Institute of Medicine   (United States)

^b UNIVERSITY OF TEXAS MEDICAL BRANCH   (United States)

^c STANFORD UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 33748675934     PISSN: 00963402     EISSN: None     Source Type: Journal    
DOI: 10.1080/00963402.2006.11461015     Document Type: Article

References (30)

1. Gregory Benford, "A Scientist's Notebook: The Biological Century," Magazine of Fantasy & Science Fiction, August 1992, pp. 73-82.
2. National Intelligence Council, Mapping the Global Future, Report of the National Intelligence Council's 2020 Project, (Washington, D.C.: Government Printing Office, 2004).
3. National Research Council, Biotechnology Research in an Age of Terrorism, (Washington, D.C.: National Academies Press, 2004).
4. On the other hand, public perception of risks can derail the expansion of technology, as evidenced by the impact of the "green" movement in Europe, where the public has generally rejected genetically engineered crops.
5. Jennifer Couzin, "Breakthrough of the Year: Small RNAs Make Big Splash," Science, December 20, 2002, pp. 2296-2297.
6. Yi Chen and Chengde Mao, "Putting a Brake on an Autonomous DNA Nanomotor," Journal of the American Chemical Society, vol. 126, no. 28, pp. 8626-8627;
7. Committee on Advances in Technology and the Prevention of Their Application to Next-Generation Biowarfare Threats, An International Perspective on Advancing Technologies and Strategies for Managing Dual-Use Risks, (Washington, D.C.: National Academies Press, 2005), pp. 49-52.
8. Brian Choi et al., "Artificial Allosteric Control of Maltose Binding protein," Physical Review Letters, vol. 94, no. 3, 2005, pp. 1-4.
9. Elliott Kagan, "Bioregulators as Instruments of Terror," Clinics in Laboratory Medicine, vol. 21, no. 3, pp. 607-618.
10. See also: Mark Wheelis, "Will the New Biology Lead to New Weapons?" Arms Control Today, July/August 2004, pp. 6-13;
11. Malcolm Dando, Biotechnology, Weapons, and Humanity (Amsterdam: Harwood Academic Publishers, 1999), especially chapter 4;
12. and Malcolm Dando, A New Form of Warfare: The Rise of Non-Lethal Weapons (Dulles, Va.: Potomac Books, Inc., 1996), especially chapters 5 and 8.
13. See swri.org/4org/d01/microenc/microen/default.htm.
14. For therapeutic applications, see Thomas Ming Swi Chang, "Therapeutic Applications of Polymeric Artificial Cells," Nature Reviews: Drug Discovery, March 2005, pp. 221-235;
15. and Gorka Orive et al., "History, Challenges, and Perspectives of Cell Microencapsulation," Trends in Biotechnology, February 2004, pp. 87-92.
16. Robert David Fleischmann et al., "Whole-Genome Random Sequencing and Assembly of Haemophilus Influenzae Rd.," Science, July 28, 1995, pp. 496-512.
17. Jay Shendure et al, "Accurate Multiplex Potony Sequencing of an Evolved Bacterial Genome," Science, September 9,2005, pp. 1728-1732;
18. Marcel Margulies et al., "Genome Sequencing in Microfabricated High-Density Picolitre Reactors," Nature, September 15, 2005, pp. 376-380.
19. Abdallah S. Daar and Peter A. Singer, "Pharmacogenetics and Geographical Ancestry: Implications for Drug Development and Global Health," Nature Reviews: Genetics, March 2005, pp. 241-246.
20. NRC/IOM, An International Perspective on Advancing Technologies and Strategies for Managing Dual-Use Risks (Washington, D.C.: National Academies Press, 2005).
21. Ibid.
22. For additional information, see dnaprint.com/welcome, and, in particular, a related site at ancestrybydna.com/welcome/home.
23. James Clive, Preview: Global Status of Commercialized Biotech/GM Crops: 2004, ISAAA Briefs no. 32, available at www.isaaa.org.
24. Committee on Advances in Technology, An International Perspective on Advancing Technologies and Strategies for Managing Dual-Use Risks.
25. James B. Petro et al., "Biotechnology: Impact on Biological Warfare and Biodefense," Biosecurity and Bioterrorism: Biodefense Strategy, Practice, and Science, vol. 1, no. 3, 2003, pp. 161-168.
26. Report of the Secretary-General, Uniting Against Terrorism: Recommendations for a Global Counterterrorism Strategy, U.N. General Assembly, Sixtieth Session, agenda items 46 and 120, April 27, 2006.
27. David A. Relman, Eileen R. Choffnes, and Stanley M. Lemon, "In Search of Biosecurity," Science, March 31, 2006, p. 1835.
28. Donald Kennedy, "A Welcome New Look," Science, June 16, 2006, p. 1573.
29. NSDD-189, "National Policy on Transfer of Scientific, Technical, and Engineering Information," September 21, 1985, available at fas.org/ irp/offdocs/nsdd/nsdd-189.htm.
30. See the National Security Archive report: "Pseudo-Secrets: A Freedom of Information Audit of the U.S. Government's Policies on Sensitive Unclassified Information," at gwu.edu/~nsarchiv/NSAEBB/ NSAEBB183/press.htm.