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note
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For further discussion, see Supporting Information.
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note
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Hindered rotation about the (O)C-N bond in the acetamide group of 1, in the examined range of temperatures, was discounted by the fact that the conformational isomerism was not observed in parallel experiments with the model compound 2.
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49
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33748598797
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note
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2 symmetrical conformations. The proposed geometry is in agreement with the available experimental results.
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50
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note
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3). Rather low affinity of TFA for amides in 1 is thus evident.
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