Cisplatin-induced expression of iron-retaining genes FIT2 and FIT3 in Saccharomyces cerevisiae

Journal of Toxicological Sciences

Volumn 31, Issue 3, 2006, Pages 287-290

  Kimura, Akiko ^a   Ohashi, Kazuaki ^a,b   Yamamoto, Reiko ^c   Naganuma, Akira ^a  

^a TOHOKU UNIVERSITY   (Japan)

^b OSAKA UNIVERSITY   (Japan)

^c SHOKEI GAKUIN UNIVERSITY   (Japan)

Author keywords

Cisplatin; Fit2; Fit3; Gene expression; Induction

Indexed keywords

CISPLATIN; IRON; MESSENGER RNA;

ARTICLE; CELL WALL; CONTROLLED STUDY; DRUG SENSITIVITY; FIT2 GENE; FIT3 GENE; GENE; GENE EXPRESSION; NONHUMAN; NORTHERN BLOTTING; SACCHAROMYCES CEREVISIAE; TRANSCRIPTION REGULATION; YEAST CELL;

SACCHAROMYCES CEREVISIAE;

EID: 33748571147     PISSN: 03881350     EISSN: 18803989     Source Type: Journal    
DOI: 10.2131/jts.31.287     Document Type: Article

References (8)

1. Birrell, G.W., Brown, J.A., Wu, H.I., Giaever, G., Chu, A.M., Davis, R.W. and Brown, J.M. (2002): Transcriptional response of Saccharomyces cerevisiae to DNA-damaging agents does not identify the genes that protect against these agents. Proc. Natl. Acad. Sci. U S A, 99, 8778-8783.
2. Einhorn, L.H. and Williams, S.D. (1979): The role of cis-platinum in solid-tumor therapy. New Engl. J. Med., 300, 289-291.
3. Furuchi, T., Hwang, G.W. and Naganuma, A. (2002): Overexpression of the ubiquitin-conjugating enzyme Cdc34 confers resistance to methylmercury in Saccharomyces cerevisiae. Mol. Pharmacol., 61, 738-741.
4. Naganuma, A., Miura, N., Kaneko, S., Mishina, T., Hosoya, S., Miyairi, S., Furuchi, T. and Kuge, S. (2000): GFAT as a target molecule of methylmercury toxicity in Saccharomyces cerevisiae. FASEB J., 14, 968-972.
5. Protchenko, O., Ferea, T., Rashford, J., Tiedeman, J., Brown, P.O., Botstein, D. and Philpott, C.C. (2001): Three cell wall mannoproteins facilitate the uptake of iron in Saccharomyces cerevisiae. J. Biol. Chem., 276, 49244-49250.
6. Siddik, Z.H. (2003): Cisplatin: Mode of cytotoxic action and molecular basis of resistance. Oncogene, 22, 7265-7279.
7. Yamaguchi-Iwai, Y., Dancis, A. and Klausner, R.D. (1995): AFT1: A mediator of iron regulated transcriptional control in Saccharomyces cerevisiae. EMBO J., 14, 1231-1239.
8. Yamaguchi-Iwai, Y., Ueta, R., Fukunaka, A. and Sasaki, R. (2002): Subcellular localization of Aft1 transcription factor responds to iron status in Saccharomyces cerevisiae. J. Biol. Chem., 277, 18914-18918.