Structural organization and expression of human MTUS1, a candidate 8p22 tumor suppressor gene encoding a family of angiotensin II AT2 receptor-interacting proteins, ATIP

Gene

Volumn 380, Issue 2, 2006, Pages 127-136

  Di Benedetto, M ^a,b,c,d   Bieche I ^e   Deshayes, F ^a,b,c,d   Vacher, S ^e   Nouet, S ^a,b,c,d   Collura, V ^f   Seitz, I ^a,b,c,d   Louis, S ^a,b,c,d   Pineau, P ^g   Amsellem Ouazana, D ^e,h   Couraud, P O ^a,b,c,d   Strosberg, A D ^a,b,c,d,f   Stoppa Lyonnet, D ⁱ   Lidereau, R ^e   Nahmias, C ^a,b,c,d  

^a INSTITUT COCHIN   (France)

^b INSERM   (France)

^c CNRS   (France)

^d UNIVERSITÉ PARIS DESCARTES   (France)

^e CENTRE RENÉ HUGUENIN   (France)

^f Hybrigenics SA   (France)

^g INSTITUT PASTEUR   (France)

^h Department of Urology ^*  (France)

ⁱ INSTITUT CURIE   (France)

Author keywords

ATIP; Brain; Cancer; Cerebellum; Human tissues; Real time RT PCR

Indexed keywords

ANGIOTENSIN 2 RECEPTOR INTERACTING PROTEIN; ANGIOTENSIN 2 RECEPTOR INTERACTING PROTEIN 1; ANGIOTENSIN 2 RECEPTOR INTERACTING PROTEIN 3; ANGIOTENSIN 2 RECEPTOR INTERACTING PROTEIN 4; ANGIOTENSIN II; DNA; GENE PRODUCT; POLYPEPTIDE; RECEPTOR PROTEIN; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ANIMAL TISSUE; ARTICLE; BLADDER; BRAIN FUNCTION; CARBOXY TERMINAL SEQUENCE; CELL MEMBRANE; CELL NUCLEUS; CEREBELLUM; CHROMOSOME 8P; COLON; CONTROLLED STUDY; CYTOSOL; EXON; GENE EXPRESSION; GENE IDENTIFICATION; GENE LOCATION; GENE STRUCTURE; GENETIC CONSERVATION; GENETIC ORGANIZATION; HETEROZYGOSITY LOSS; HUMAN; HUMAN TISSUE; MITOCHONDRIAL TUMOR SUPPRESSOR 1 GENE; NONHUMAN; NUCLEOTIDE SEQUENCE; OVARY; PRIORITY JOURNAL; PROSTATE; PROTEIN DOMAIN; PROTEIN FAMILY; PROTEIN LOCALIZATION; TISSUE DISTRIBUTION; TUMOR SUPPRESSOR GENE;

ALTERNATIVE SPLICING; BASE SEQUENCE; BLOTTING, NORTHERN; CENTRAL NERVOUS SYSTEM; CHROMOSOME MAPPING; CHROMOSOMES, HUMAN, PAIR 8; EVOLUTION, MOLECULAR; EXONS; FEMALE; GENE EXPRESSION; GENES, TUMOR SUPPRESSOR; HUMANS; INTRONS; MALE; MULTIGENE FAMILY; RECEPTOR, ANGIOTENSIN, TYPE 2; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SEQUENCE ANALYSIS; SEQUENCE HOMOLOGY, AMINO ACID; TISSUE DISTRIBUTION; TUMOR SUPPRESSOR PROTEINS; VARIATION (GENETICS);

EID: 33748555191     PISSN: 03781119     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.gene.2006.05.021     Document Type: Article

References (38)

1. Allen A.M., MacGregor D.P., McKinley M.J., and Mendelsohn F.A. Angiotensin II receptors in the human brain. Regul. Pept. 79 (1999) 1-7
2. Bieche I., et al. Identification of CGA as a novel estrogen receptor-responsive gene in breast cancer: an outstanding candidate marker to predict the response to endocrine therapy. Cancer Res. 61 (2001) 1652-1658
3. Bieche I., et al. Expression of stathmin family genes in human tissues: non-neural-restricted expression for SCLIP. Genomics 81 (2003) 400-410
4. Bienvenu T., et al. Rare polymorphic variants of the AGTR2 gene in boys with non-specific mental retardation. J. Med. Genet. 40 (2003) 357-359
5. Birney E., Clamp M., and Durbin R. Genewise and genomewise. Genome Res. 14 (2004) 988-995
6. Brickley K., Smith M.J., Beck M., and Stephenson F.A. GRIF-1 and OIP106, members of a novel gene family of coiled-coil domain proteins: association in vivo and in vitro with kinesin. J. Biol. Chem. 280 (2005) 14723-14732
7. Chang L., and Goldman R.D. Intermediate filaments mediate cytoskeletal crosstalk. Nat. Rev., Mol. Cell Biol. 5 (2004) 601-613
8. Choi C., Kim M.H., Juhng S.W., and Oh B.R. Loss of heterozygosity at chromosome segments 8p22 and 8p11.2-21.1 in transitional-cell carcinoma of the urinary bladder. Int. J. Cancer 86 (2000) 501-505
9. Cote F., Do T.H., Laflamme L., Gallo J.M., and Gallo-Payet N. Activation of the AT(2) receptor of angiotensin II induces neurite outgrowth and cell migration in microexplant cultures of the cerebellum. J. Biol. Chem. 274 (1999) 31686-31692
10. Deshayes F., and Nahmias C. Angiotensin receptors: a new role in cancer?. Trends Endocrinol. Metab. 16 (2005) 293-299
11. Di Benedetto M., et al. Mutation analysis of the 8p22 candidate tumor suppressor gene ATIP/MTUS1 in hepatocellular carcinoma. Mol. Cell. Endocrinol. 252 (2006) 207-215
12. Fromont G., et al. Allelic losses in localized prostate cancer: association with prognostic factors. J. Urol. 170 (2003) 1394-1397
13. Fujiwara, Ohata H., Kuroki T., Koyama K., Tsuchiya E., Monden M., and Nakamura Y. Isolation of a candidate tumor suppressor gene on chromosome 8p21.3-p22 that is homologous to an extracellular domain of the PDGF receptor beta gene. Oncogene 10 (1995) 891-895
14. Galtier N., Gouy M., and Gautier C. SEAVIEW and PHYLO_WIN: two graphic tools for sequence alignment and molecular phylogeny. Comput. Appl. Biosci. 12 (1996) 543-548
15. Goodstadt L., and Ponting C.P. CHROMA: consensus-based colouring of multiple alignments for publication. Bioinformatics 17 (2001) 845-846
16. Gustafson C.E., et al. Functional evidence for a colorectal cancer tumor suppressor gene at chromosome 8p22-23 by monochromosome transfer. Cancer Res. 56 (1996) 5238-5245
17. Hein L., Barsh G.S., Pratt R.E., Dzau V.J., and Kobilka B.K. Behavioural and cardiovascular effects of disrupting the angiotensin II type-2 receptor in mice. Nature 377 (1995) 744-747
18. Horiuchi M., Lehtonen J.Y., and Daviet L. Signaling mechanism of the AT2 angiotensin II receptor: crosstalk between AT1 and AT2 receptors in cell growth. Trends Endocrinol. Metab. 10 (1999) 391-396
19. Huang X., and Madan A. CAP3: a DNA sequence assembly program. Genome Res. 9 (1999) 868-877
20. Ichiki T., et al. Effects on blood pressure and exploratory behaviour of mice lacking angiotensin II type-2 receptor. Nature 377 (1995) 748-750
21. Lazard D., Briend-Sutren M.M., Villageois P., Mattei M.G., Strosberg A.D., and Nahmias C. Molecular characterization and chromosome localization of a human angiotensin II AT2 receptor gene highly expressed in fetal tissues. Recept. Channels 2 (1994) 271-280
22. Lerebours F., et al. Evidence of chromosome regions and gene involvement in inflammatory breast cancer. Int. J. Cancer 102 (2002) 618-622
23. Li J., et al. Angiotensin AT2 receptor protects against cerebral ischemia-induced neuronal injury. FASEB J. 19 (2005) 617-619
24. Macias M.J., Wiesner S., and Sudol M. WW and SH3 domains, two different scaffolds to recognize proline-rich ligands. FEBS Lett. 513 (2002) 30-37
25. Marchler-Bauer A., et al. CDD: a conserved domain database for protein classification. Nucleic Acids Res. 33 (2005) D192-D196
26. Nouet S., and Nahmias C. Signal transduction from the angiotensin II AT2 receptor. Trends Endocrinol. Metab. 11 (2000) 1-6
27. Nouet S., et al. Trans-inactivation of receptor tyrosine kinases by novel angiotensin II AT2 receptor-interacting protein, ATIP. J. Biol. Chem. 279 (2004) 28989-28997
28. Pils D., et al. Five genes from chromosomal band 8p22 are significantly down-regulated in ovarian carcinoma. Cancer 104 (2005) 2417-2429
29. Pineau P., et al. Identification of three distinct regions of allelic deletions on the short arm of chromosome 8 in hepatocellular carcinoma. Oncogene 18 (1999) 3127-3134
30. Seibold S., Rudroff C., Weber M., Galle J., Wanner C., and Marx M. Identification of a new tumor suppressor gene located at chromosome 8p21.3-22. FASEB J. 17 (2003) 1180-1182
31. Shapiro M.B., and Senapathy P. RNA splice junctions of different classes of eukaryotes: sequence statistics and functional implications in gene expression. Nucleic Acids Res. 15 (1987) 7155-7174
32. Steckelings U.M., Kaschina E., and Unger T. The AT2 receptor-a matter of love and hate. Peptides 26 (2005) 1401-1409
33. Sumners C., and Gelband C.H. Neuronal ion channel signalling pathways: modulation by angiotensin II. Cell. Signal. 10 (1998) 303-311
34. Vervoort V.S., et al. AGTR2 mutations in X-linked mental retardation. Science 296 (2002) 2401-2403
35. Weksler B.B., et al. Blood-brain barrier-specific properties of a human adult brain endothelial cell line. FASEB J. 19 (2005) 1872-1874
36. Wistuba II, et al. Allelic losses at chromosome 8p21-23 are early and frequent events in the pathogenesis of lung cancer. Cancer Res. 59 (1999) 1973-1979
37. Wruck C.J., et al. Regulation of transport of the angiotensin AT2 receptor by a novel membrane-associated Golgi protein. Arterioscler. Thromb. Vasc. Biol. 25 (2005) 57-64
38. Zhou X., Jordan R.C., Li Y., Huang B.L., and Wong D.T. Frequent allelic imbalances at 8p and 11q22 in oral and oropharyngeal epithelial dysplastic lesions. Cancer Genet. Cytogenet. 161 (2005) 86-89