MEK inhibitor PD98059 acutely inhibits synchronized spontaneous Ca 2+ oscillations in cultured hippocampal networks

Acta Pharmacologica Sinica

Volumn 27, Issue 7, 2006, Pages 869-876

  Rui, Yan Fang ^a   Sun, Zhao Hui ^a   Gu, Jia Ping ^a   Sheng, Zhong Hua ^a   He, Xiang Ping ^a   Xie, Zuo Ping ^a  

^a TSINGHUA UNIVERSITY   (China)

Author keywords

Calcium oscillation; MEK; PD98059

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 4 AMINOBUTYRIC ACID RECEPTOR; 4 ETHYL 2 (4 METHOXYPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; CALCIUM; DYE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BRAIN NERVE CELL; CALCIUM SIGNALING; CELL CULTURE; CELL LEVEL; CONTROLLED STUDY; DOSE RESPONSE; DRUG BIOAVAILABILITY; DRUG EFFECT; DRUG INHIBITION; ELECTRON MICROSCOPY; HIPPOCAMPUS; IMAGING SYSTEM; NONHUMAN;

ANIMALS; CALCIUM SIGNALING; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; FETUS; FLAVONOIDS; HIPPOCAMPUS; IMIDAZOLES; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; NEURONS; RATS;

EID: 33748542295     PISSN: 16714083     EISSN: 17457254     Source Type: Journal    
DOI: 10.1111/j.1745-7254.2006.00387.x     Document Type: Article

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