Apolipoprotein E modulates establishment of HSV-1 latency and survival in a mouse ocular model

Current Eye Research

Volumn 31, Issue 9, 2006, Pages 703-708

  Bhattacharjee, Partha S ^a   Neumann, Donna M ^a   Stark, David ^a   Thompson, Hilary W ^a   Hill, James M ^b,c  

^a LOUISIANA STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b LOUISIANA STATE UNIVERSITY HEALTH SCIENCES CENTER   (United States)

^c LSU EYE CENTER   (United States)

Author keywords

Apolipoprotein E; HSV 1; Latency; Mouse; Neuroinvasiveness; Neurovirulence; Ocular

Indexed keywords

APOLIPOPROTEIN E; GENOMIC RNA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; FEMALE; GENOTYPE; HERPES SIMPLEX VIRUS 1; MOUSE; NONHUMAN; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; SLIT LAMP; TEAR FILM; VIRAL EYE INFECTION; VIRULENCE; VIRUS LATENCY; VIRUS REPLICATION; VIRUS SURVIVAL;

ANIMALS; APOLIPOPROTEINS E; CORNEA; DISEASE MODELS, ANIMAL; DNA, VIRAL; FEMALE; GENOME, VIRAL; HERPESVIRUS 1, HUMAN; KERATITIS, HERPETIC; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; POLYMERASE CHAIN REACTION; SURVIVAL RATE; VIRULENCE; VIRUS LATENCY; VIRUS REPLICATION;

EID: 33748525170     PISSN: 02713683     EISSN: 14602202     Source Type: Journal    
DOI: 10.1080/02713680600864600     Document Type: Article

References (28)

1. Itzhaki R, Wozniak M. Herpes simplex virus type 1, apolipoprotein E, and cholesterol: A dangerous liason in Azheimer's disease and other disorders. Prog Lipid Res. 2006;45:73-90.
2. Itzhaki RF, Dobson CB, Shipley SJ, Wozniak MA. The role of viruses and of APOE in dementia. Ann N Y Acad Sci. 2004;1019:15-18.
3. Itzhaki RF, Wozniak M, Dobson C, Lin WR. ApoE viral interactions. Nat Med. 1998;4:1344.
4. Beffert U, Bertrand P, Champagne D, et al. HSV-1 in brain and risk of Alzheimer's disease. Lancet. 1998;351:1330-1331.
5. Itabashi S, Arai H, Matsui T, et al. Herpes simplex virus and risk of Alzheimer's disease. Lancet. 1997;349:1102.
6. Burgos JS, Ramirez C, Sastre I, et al. Herpes simplex virus type 1 infection via the bloodstream with apolipoprotein E dependence in the gonads is influenced by gender. J Virol. 2005;79:1605-1612.
7. Burgos JS, Ramirez C, Sastre I, et al. Involvement of apolipoprotein E in the hematogenous route of herpes simplex virus type 1 to the central nervous system. J Virol. 2002;76:12394-12398.
8. Burgos JS, Ramirez C, Sastre I, et al. ApoE4 is more efficient than E3 in brain access by herpes simplex virus type 1. Neuroreport. 2003;14:1825-1827.
9. Burgos JS, Ramirez C, Sastre I, Valdivieso F. Effect of apolipoprotein E on the cerebral load of latent herpes simplex virus type 1 DNA. J Virol. 2006;80:5383-5387.
10. Mahley RW, Rall SC. Jr. Apolipoprotein E: Far more than a lipid transport protein. Annu Rev Genomics Hum Genet. 2000;1:507-537.
11. Weisgraber KH, Roses AD, Strittmatter WJ. The role of apolipoprotein E in the nervous system. Curr Opin Lipidol. 1994;5:110-116.
12. Horsburgh K, McCulloch J, Nilsen M, et al. Intraventricular infusion of apolipoprotein E ameliorates acute neuronal damage after global cerebral ischemia in mice. J Cereb Blood Flow Metabol. 2000;20:458-462.
13. Lynch JR, Wang H, Mace B, et al. A novel therapeutic derived from apolipoprotein E reduces brain inflammation and improves outcome after closed head injury. Exp Neurol. 2005;192:109-116.
14. Lahiri DK. Apolipoprotein E as a target for developing new therapeutics for Alzheimer's disease based on studies from protein, RNA, and regulatory region of the gene. J Mol Neurosci. 2004;23:225-233.
15. Brown SM, Ritchie DA, Subak-Sharpe JH. Genetic studies with herpes simplex virus type 1. The isolation of temperature-sensitive mutants, their arrangement into complementation groups and recombination analysis leading to a linkage map. J Gen Virol. 1973;18:329-346.
16. Cook SD, Paveloff MJ, Doucet JJ, et al. Ocular herpes simplex virus reactivation in mice latently infected with latency-associated transcript mutants. Invest Ophthalmol Vis Sci. 1991;32:1558-1561.
17. Loutsch JM, Sainz B, Jr. Marquart ME, et al. Effect of famciclovir on herpes simplex virus type 1 corneal disease and establishment of latency in rabbits. Antimicrob Agents Chemother. 2001;45:2044-2053.
18. Marquart M, Bhattacharjee P, Zheng X, et al. Ocular reactivation phenotype of HSV-1 strain F(MP)E, a corticosteroid-sensitive strain. Curr Eye Res. 2003;26:205-209.
19. Marquart ME, Zheng X, Tran RK, et al. A cAMP response element within the latency-associated transcript promoter of HSV-1 facilitates induced ocular reactivation in a mouse hyperthermia model. Virology. 2001;284:62-69.
20. Sawtell NM. Quantitative analysis of herpes simplex virus reactivation in vivo demonstrates that reactivation in the nervous system is not inhibited at early times postinoculation. J Virol. 2003;77:4127-4138.
21. Gebhardt BM, Kaufman HE, Hill JM. Effect of acyclovir on thermal stress-induced herpesvirus reactivation. Curr Eye Res. 2004;29:137-144.
22. Gebhardt BM, Varnell ED, Kaufman HE. Acetylsalicylic acid reduces viral shedding induced by thermal stress. Curr Eye Res. 2004;29:119-126.
23. Chen X-P, Mata M, Kelley M, et al. The relationship of herpes simplex virus latency associated transcript expression to genome copy number: A quantitative study using laser capture microdissection. J Neurovirol. 2002;8:204-210.
24. Cohrs RJ, Randall J, Smith J, et al. Analysis of individual human trigeminal ganglia for latent herpes simplex virus type 1 and varicella-zoster virus nucleic acids using real-time PCR. J Virol. 2000;74:11464-11471.
25. Pevenstein SR, Williams RK, McChesney D, et al. Quantitation of latent varicella-zoster virus and herpes simplex virus genomes in human trigeminal ganglia. J Virol. 1999;73:10514-10518.
26. Poirier J, Minnich A, Davignon J. Apolipoprotein E, synaptic plasticity and Alzheimer's disease. Ann Med. 1995;27:663-670.
27. Huemer HP, Menzel HJ, Potratz D, et al. Herpes simplex virus binds to human serum lipoprotein. Intervirology. 1988;29:68-76.
28. Weisberger KH. Apolipoprotein E: Structure:function relationships. Adv. Protein Chem. 1994;45:249-302.