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Volumn 177, Issue 6, 2006, Pages 4141-4148

Opposing actions of Stat1 and Stat6 on IL-13-induced up-regulation of early growth response-1 and platelet-derived growth factor ligands in pulmonary fibroblasts

Author keywords

[No Author keywords available]

Indexed keywords

EARLY GROWTH RESPONSE FACTOR 1; INTERLEUKIN 13; MESSENGER RNA; PLATELET DERIVED GROWTH FACTOR; PLATELET DERIVED GROWTH FACTOR A; PLATELET DERIVED GROWTH FACTOR AA; PLATELET DERIVED GROWTH FACTOR C; PLATELET DERIVED GROWTH FACTOR CC; STAT1 PROTEIN; STAT6 PROTEIN; UNCLASSIFIED DRUG;

EID: 33748483271     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.177.6.4141     Document Type: Article
Times cited : (45)

References (43)
  • 3
    • 0035030820 scopus 로고    scopus 로고
    • IL-4, IL-13, and dexamethasone augment fibroblast proliferation in asthma
    • Kraft, M., C. Lewis, D. Pham, and H.W. Chu. 2001. IL-4, IL-13, and dexamethasone augment fibroblast proliferation in asthma. J. Allergy Clin. Immunol. 107: 602-606.
    • (2001) J. Allergy Clin. Immunol. , vol.107 , pp. 602-606
    • Kraft, M.1    Lewis, C.2    Pham, D.3    Chu, H.W.4
  • 4
    • 9444299027 scopus 로고    scopus 로고
    • IL-13 and IL-1β promote lung fibroblast growth through coordinated up-regulation of PDGF-AA and PDGF-Rα
    • Ingram, J. L., A. B. Rice, K. Geisenhoffer, D. K. Madtes, and J. C. Bonner. 2004. IL-13 and IL-1β promote lung fibroblast growth through coordinated up-regulation of PDGF-AA and PDGF-Rα. FASEB J. 18: 1132-1134.
    • (2004) FASEB J. , vol.18 , pp. 1132-1134
    • Ingram, J.L.1    Rice, A.B.2    Geisenhoffer, K.3    Madtes, D.K.4    Bonner, J.C.5
  • 5
    • 2942682928 scopus 로고    scopus 로고
    • Regulation of PDGF and its receptors in fibrotic diseases
    • Bonner, J. C. 2004. Regulation of PDGF and its receptors in fibrotic diseases. Cytokine Growth Factor Rev. 15: 255-273.
    • (2004) Cytokine Growth Factor Rev. , vol.15 , pp. 255-273
    • Bonner, J.C.1
  • 6
    • 0346096889 scopus 로고    scopus 로고
    • Modulation of PDGF-C and PDGF-D expression during bleomycin-induced lung fibrosis
    • Zhuo, Y., J. Zhang, M. Laboy, and J. A. Lasky. 2004. Modulation of PDGF-C and PDGF-D expression during bleomycin-induced lung fibrosis. Am. J. Physiol. 286: L182-L188.
    • (2004) Am. J. Physiol. , vol.286
    • Zhuo, Y.1    Zhang, J.2    Laboy, M.3    Lasky, J.A.4
  • 8
    • 0035794217 scopus 로고    scopus 로고
    • DNA binding specificity of different STAT proteins: Comparison of in vitro specificity with natural target sites
    • Ehret, G. B., P. Reichenbach, U. Schindler, C. M. Horvath, S. Fritz, M. Nabholz, and P. Bucher. 2001. DNA binding specificity of different STAT proteins: comparison of in vitro specificity with natural target sites. J. Biol. Chem. 276: 6675-6688.
    • (2001) J. Biol. Chem. , vol.276 , pp. 6675-6688
    • Ehret, G.B.1    Reichenbach, P.2    Schindler, U.3    Horvath, C.M.4    Fritz, S.5    Nabholz, M.6    Bucher, P.7
  • 9
    • 0032536837 scopus 로고    scopus 로고
    • Signal transducer and activator of transcription factor 6 (Stat6)-deficient mice are protected from antigen-induced airway hyperresponsiveness and mucus production
    • Kuperman, D., B. Schofield, M. Wills-Karp, and M. J. Grusby. 1998. Signal transducer and activator of transcription factor 6 (Stat6)-deficient mice are protected from antigen-induced airway hyperresponsiveness and mucus production. J. Exp. Med. 187: 939-948.
    • (1998) J. Exp. Med. , vol.187 , pp. 939-948
    • Kuperman, D.1    Schofield, B.2    Wills-Karp, M.3    Grusby, M.J.4
  • 10
    • 3142622926 scopus 로고    scopus 로고
    • STAT-1 is activated by IL-4 and IL-13 in multiple cell types
    • Wang, I.-M., H. Lin, S. J. Goldman, and M. Kobayashi. 2004. STAT-1 is activated by IL-4 and IL-13 in multiple cell types. Mol. Immunol. 41: 873-884.
    • (2004) Mol. Immunol. , vol.41 , pp. 873-884
    • Wang, I.-M.1    Lin, H.2    Goldman, S.J.3    Kobayashi, M.4
  • 11
    • 15444366460 scopus 로고    scopus 로고
    • Uteroglobin suppresses SCCA gene expression associated with allergic asthma
    • Ray, R., M. Choi, Z. Zhang, G. A. Silverman, D. Askew, and A. B. Mukherjee. 2005. Uteroglobin suppresses SCCA gene expression associated with allergic asthma. J. Biol. Chem. 280: 9761-9764.
    • (2005) J. Biol. Chem. , vol.280 , pp. 9761-9764
    • Ray, R.1    Choi, M.2    Zhang, Z.3    Silverman, G.A.4    Askew, D.5    Mukherjee, A.B.6
  • 12
    • 3142694849 scopus 로고    scopus 로고
    • Cell proliferation and STAT6 pathways are negatively regulated in T cells by STAT1 and suppressors of cytokine signaling
    • Yu, C.-R., R. M. Mahdi, S. Ebong, B. P. Vistica, J. Chen, Y. Guo, I. Gery, and C. E. Ewuagu. 2004. Cell proliferation and STAT6 pathways are negatively regulated in T cells by STAT1 and suppressors of cytokine signaling. J. Immunol. 173: 737-746.
    • (2004) J. Immunol. , vol.173 , pp. 737-746
    • Yu, C.-R.1    Mahdi, R.M.2    Ebong, S.3    Vistica, B.P.4    Chen, J.5    Guo, Y.6    Gery, I.7    Ewuagu, C.E.8
  • 13
    • 4344627594 scopus 로고    scopus 로고
    • Inhibition of signal transducer and activator of transcription 1 attentuates allergen-induced airway inflammation and hyperreactivity
    • Quarcoo, D., S. Weixler, D. Groneberg, R. Joachim, B. Ahrens, A. H. Wagner, M. Hecker, and E. Hamelmann. 2004. Inhibition of signal transducer and activator of transcription 1 attentuates allergen-induced airway inflammation and hyperreactivity. J. Allergy Clin. Immunol. 114: 288-295.
    • (2004) J. Allergy Clin. Immunol. , vol.114 , pp. 288-295
    • Quarcoo, D.1    Weixler, S.2    Groneberg, D.3    Joachim, R.4    Ahrens, B.5    Wagner, A.H.6    Hecker, M.7    Hamelmann, E.8
  • 18
    • 0036888651 scopus 로고    scopus 로고
    • Regulation of life and death by the zinc finger transcription factor Egr-1
    • Thiel, G., and G. Cibelli. 2002. Regulation of life and death by the zinc finger transcription factor Egr-1. J. Cell. Physiol. 193: 287-292.
    • (2002) J. Cell. Physiol. , vol.193 , pp. 287-292
    • Thiel, G.1    Cibelli, G.2
  • 19
    • 4644362064 scopus 로고    scopus 로고
    • Fibroblast growth factor-2 induction of platelet-derived growth factor-C chain transcription in vascular smooth muscle cells is ERK-dependent but not JNK-dependent and mediated by Egr-1
    • Midgley, V. C., and M. Levon. 2004. Fibroblast growth factor-2 induction of platelet-derived growth factor-C chain transcription in vascular smooth muscle cells is ERK-dependent but not JNK-dependent and mediated by Egr-1. J. Biol. Chem. 279: 40289-40295.
    • (2004) J. Biol. Chem. , vol.279 , pp. 40289-40295
    • Midgley, V.C.1    Levon, M.2
  • 25
    • 0033560126 scopus 로고    scopus 로고
    • Pulmonary expression of interleukin-13 causes inflammation, mucus hypersecretion, subepithelial fibrosis, physiologic abnormalities, and eotaxin production
    • Zhu, Z., R. J. Homer, Z. Wang, Q. Chen, G. P. Geba, J. Wang, Y. Zhang, and J. A. Elias. 1999. Pulmonary expression of interleukin-13 causes inflammation, mucus hypersecretion, subepithelial fibrosis, physiologic abnormalities, and eotaxin production. J. Clin. Invest. 103: 779-788.
    • (1999) J. Clin. Invest. , vol.103 , pp. 779-788
    • Zhu, Z.1    Homer, R.J.2    Wang, Z.3    Chen, Q.4    Geba, G.P.5    Wang, J.6    Zhang, Y.7    Elias, J.A.8
  • 27
    • 0036625960 scopus 로고    scopus 로고
    • The role of STATs in apoptosis
    • Battle, T. E., and D. A. Frank. 2002. The role of STATs in apoptosis. Curr. Mol. Med. 2: 381-392.
    • (2002) Curr. Mol. Med. , vol.2 , pp. 381-392
    • Battle, T.E.1    Frank, D.A.2
  • 28
    • 0035852765 scopus 로고    scopus 로고
    • Constitutively activated Stat3 protects fibroblasts from serum withdrawal and UV-induced apoptosis and antagonizes the proapoptotic effects of activated Stat1
    • Shen, Y., G. Devgan, J. E. Darnell, Jr., and J. F. Bromberg. 2001. Constitutively activated Stat3 protects fibroblasts from serum withdrawal and UV-induced apoptosis and antagonizes the proapoptotic effects of activated Stat1. Proc. Natl. Acad. Sci. USA 98: 1543-1548.
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 1543-1548
    • Shen, Y.1    Devgan, G.2    Darnell Jr., J.E.3    Bromberg, J.F.4
  • 30
    • 27144506985 scopus 로고    scopus 로고
    • Induction of uteroglobin-related protein 2 (Ugrp2) gene expression by the Th2 cytokines IL-4 and IL-13
    • Yamada, A., F. Sheikh, T. Niimi, F. J. DeMayo, A. D. Keegan, R. P. Donnelly, and S. Kimura. 2005. Induction of uteroglobin-related protein 2 (Ugrp2) gene expression by the Th2 cytokines IL-4 and IL-13. J. Immunol. 175: 5708-5715.
    • (2005) J. Immunol. , vol.175 , pp. 5708-5715
    • Yamada, A.1    Sheikh, F.2    Niimi, T.3    Demayo, F.J.4    Keegan, A.D.5    Donnelly, R.P.6    Kimura, S.7
  • 31
    • 0031308702 scopus 로고    scopus 로고
    • IL-4-induced STAT6 suppresses IFN-γ-stimulated STAT1-dependent transcription in mouse macrophages
    • Ohmori, Y., and T. A. Hamilton. 1997. IL-4-induced STAT6 suppresses IFN-γ-stimulated STAT1-dependent transcription in mouse macrophages. J. Immunol. 159: 5474-5482.
    • (1997) J. Immunol. , vol.159 , pp. 5474-5482
    • Ohmori, Y.1    Hamilton, T.A.2
  • 32
    • 0035026482 scopus 로고    scopus 로고
    • Lysophosphatidylcholine induces early growth response factor-1 expression and activates the core promoter of PDGF-A chain in vascular endothelial cells
    • Morimoto, M., N. Kume, S. Miyamoto, Y. Ueno, H. Kataoka, M. Minami, K. Hayashida, N. Hashimoto, and T. Kita. 2001. Lysophosphatidylcholine induces early growth response factor-1 expression and activates the core promoter of PDGF-A chain in vascular endothelial cells. Arterioscler. Thromb. Vasc. Biol. 21: 771-776.
    • (2001) Arterioscler. Thromb. Vasc. Biol. , vol.21 , pp. 771-776
    • Morimoto, M.1    Kume, N.2    Miyamoto, S.3    Ueno, Y.4    Kataoka, H.5    Minami, M.6    Hayashida, K.7    Hashimoto, N.8    Kita, T.9
  • 33
    • 0033588226 scopus 로고    scopus 로고
    • Angiotensin II (ATII)-inducible platelet-derived growth factor A-chain gene expression is p42/44 extracellular signal-regulated kinase-1/2 and Egr-1-dependent and mediated via the ATII type 1 but not type 2 receptor: Induction by ATII antagonized by nitric oxide
    • Day, F. L., L. A. Rafty, C. N. Chesterman, and L. M. Khachigian. 1999. Angiotensin II (ATII)-inducible platelet-derived growth factor A-chain gene expression is p42/44 extracellular signal-regulated kinase-1/2 and Egr-1-dependent and mediated via the ATII type 1 but not type 2 receptor: induction by ATII antagonized by nitric oxide. J. Biol. Chem. 274: 23726-23733.
    • (1999) J. Biol. Chem. , vol.274 , pp. 23726-23733
    • Day, F.L.1    Rafty, L.A.2    Chesterman, C.N.3    Khachigian, L.M.4
  • 34
    • 3242657297 scopus 로고    scopus 로고
    • SOCS: Role in inflammation, allergy and homeostasis
    • Elliott, J., and J. A. Johnston. 2004. SOCS: role in inflammation, allergy and homeostasis. Trends Immunol. 25: 434-440.
    • (2004) Trends Immunol. , vol.25 , pp. 434-440
    • Elliott, J.1    Johnston, J.A.2
  • 35
    • 1542637052 scopus 로고    scopus 로고
    • Activation of STAT signaling pathways and induction of suppressors of cytokine signaling (SOCS) proteins in mammalian lens by growth factors
    • Ebong, S., C. R. Yu, D. A. Carper, A. B. Chepelinsky, and C. E. Egwuagu. 2004. Activation of STAT signaling pathways and induction of suppressors of cytokine signaling (SOCS) proteins in mammalian lens by growth factors. Invest. Ophthalmol. Vis. Sci. 45: 872-878.
    • (2004) Invest. Ophthalmol. Vis. Sci. , vol.45 , pp. 872-878
    • Ebong, S.1    Yu, C.R.2    Carper, D.A.3    Chepelinsky, A.B.4    Egwuagu, C.E.5
  • 36
    • 0345447641 scopus 로고    scopus 로고
    • IL-4 and IL-13 induce SOCS-1 gene expression in A549 cells by three functional STAT6-binding motifs located upstream of the transcription initiation site
    • Hebenstreit, D., P. Luft, A. Schmiedlechner, G. Regl, A. M. Frischauf, F. Aberger, A. Duschl, and J. Horejs-Hoeck. 2003. IL-4 and IL-13 induce SOCS-1 gene expression in A549 cells by three functional STAT6-binding motifs located upstream of the transcription initiation site. J. Immunol. 171: 5901-5907.
    • (2003) J. Immunol. , vol.171 , pp. 5901-5907
    • Hebenstreit, D.1    Luft, P.2    Schmiedlechner, A.3    Regl, G.4    Frischauf, A.M.5    Aberger, F.6    Duschl, A.7    Horejs-Hoeck, J.8
  • 37
    • 31044435286 scopus 로고    scopus 로고
    • ERK1/2 mitogen-activated protein kinase selectively mediates IL-13-induced lung inflammation and remodeling in vivo. J
    • Lee, P. J., X. Zhang, P. Shan, B. Ma, C. G. Lee, R. J. Homer, Z. Zhu, M. Rincon, B. T. Mossman, and J. A. Elias. 2006. ERK1/2 mitogen-activated protein kinase selectively mediates IL-13-induced lung inflammation and remodeling in vivo. J. Clin. Invest. 116: 163-173.
    • (2006) Clin. Invest. , vol.116 , pp. 163-173
    • Lee, P.J.1    Zhang, X.2    Shan, P.3    Ma, B.4    Lee, C.G.5    Homer, R.J.6    Zhu, Z.7    Rincon, M.8    Mossman, B.T.9    Elias, J.A.10
  • 38
    • 0028244745 scopus 로고
    • Platelet-derived growth factor and its receptor in lungs from patients with asthma and chronic airflow obstruction
    • Aubert, J. D., S. Hayashi, J. Hards, T. R. Bai, P. D. Pare, and J. C. Hogg. 1994. Platelet-derived growth factor and its receptor in lungs from patients with asthma and chronic airflow obstruction. Am. J. Physiol. 266(6 Pt. 1): L655-L663.
    • (1994) Am. J. Physiol. , vol.266 , Issue.6 PART 1
    • Aubert, J.D.1    Hayashi, S.2    Hards, J.3    Bai, T.R.4    Pare, P.D.5    Hogg, J.C.6
  • 40
    • 0034697902 scopus 로고    scopus 로고
    • Regulation of interleukin-1β-induced platelet-derived growth factor receptor α expression in rat pulmonary myofibroblasts by p38 mitogen-activated protein kinase
    • Wang, Y. Z., P. Zhang, A. B. Rice, and J. C. Bonner. 2000. Regulation of interleukin-1β-induced platelet-derived growth factor receptor α expression in rat pulmonary myofibroblasts by p38 mitogen-activated protein kinase. J. Biol. Chem. 275: 22550-22557.
    • (2000) J. Biol. Chem. , vol.275 , pp. 22550-22557
    • Wang, Y.Z.1    Zhang, P.2    Rice, A.B.3    Bonner, J.C.4
  • 41
    • 0030471935 scopus 로고    scopus 로고
    • Basic fibroblast growth factor induces expression of the PDGF receptor α on human bronchial smooth muscle cells
    • Bonner, J. C., A. Badgett, P. M. Lindroos, and P. G. Coin. 1996. Basic fibroblast growth factor induces expression of the PDGF receptor α on human bronchial smooth muscle cells. Am. J. Physiol. 271(6 Pt. 1): L880-L888.
    • (1996) Am. J. Physiol. , vol.271 , Issue.6 PART 1
    • Bonner, J.C.1    Badgett, A.2    Lindroos, P.M.3    Coin, P.G.4
  • 42
    • 0030002546 scopus 로고    scopus 로고
    • Lipopolysaccharide up-regulates platelet-derived growth factor (PDGF) α-receptor expression in rat lung myofibroblasts and enhances response to all PDGF isoforms
    • Coin, P. G., P. M. Lindroos, G. S. Bird, A. R. Osornio-Vargas, V. L. Roggli, and J. C. Bonner. 1996. Lipopolysaccharide up-regulates platelet-derived growth factor (PDGF) α-receptor expression in rat lung myofibroblasts and enhances response to all PDGF isoforms. J. Immunol. 156: 4797-4806.
    • (1996) J. Immunol. , vol.156 , pp. 4797-4806
    • Coin, P.G.1    Lindroos, P.M.2    Bird, G.S.3    Osornio-Vargas, A.R.4    Roggli, V.L.5    Bonner, J.C.6
  • 43
    • 19444380576 scopus 로고    scopus 로고
    • Analysis of growth factors and inflammatory cytokines in exhaled breath condensate from asthmatic children
    • Leung, T.-F., G. W. K. Wong, F. W. S. Ko, C.-Y. Li, E. Yung, C. W. K. Lam, and T.-F. Fok. 2005. Analysis of growth factors and inflammatory cytokines in exhaled breath condensate from asthmatic children. Int. Arch. Allergy Immunol. 137: 66-72.
    • (2005) Int. Arch. Allergy Immunol. , vol.137 , pp. 66-72
    • Leung, T.-F.1    Wong, G.W.K.2    Ko, F.W.S.3    Li, C.-Y.4    Yung, E.5    Lam, C.W.K.6    Fok, T.-F.7


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