Optimizing vector application for gene transfer into human hepatoblastoma cells

Pediatric Surgery International

Volumn 22, Issue 9, 2006, Pages 733-742

  Warmann, Steven W ^a   Armeanu, Sorin ^b   Heitmann, Heike ^a   Ruck, Peter ^c   Seitz, Guido ^a   Wessels, Johannes T ^d   Lemken, Marie Luise ^b   Lauer, Ulrich M ^b   Fuchs, Jörg ^a   Bitzer, Michael ^b  

^a UNIVERSITY OF TÜBINGEN   (Germany)

^b UNIVERSITY HOSPITAL TÜBINGEN   (Germany)

^c Krankenhaus Leonberg   (Germany)

^d Center of Internal Medicine   (Germany)

Author keywords

Gene therapy; Hepatoblastoma; Liver specific promoters; Viral vectors

Indexed keywords

ADENOVIRUS VECTOR; GREEN FLUORESCENT PROTEIN; LIPOFECTAMINE; LUCIFERASE;

APOPTOSIS; ARTICLE; CANCER CELL; CELL ACTIVITY; CONTROLLED STUDY; FLOW CYTOMETRY; GENE TRANSFER; GENE VECTOR; GENETIC TRANSFECTION; HEPATOBLASTOMA; HUMAN; HUMAN CELL; LIPID TRANSPORT; PRIORITY JOURNAL; SENDAI VIRUS; TRANSCRIPTION INITIATION;

ADENOVIRIDAE; CELL LINE, TUMOR; DRUG CARRIERS; GENETIC VECTORS; GREEN FLUORESCENT PROTEINS; HEPATOBLASTOMA; HUMANS; LIPIDS; LIVER NEOPLASMS; PROMOTER REGIONS (GENETICS); PROMOTER REGIONS, GENETIC; SENDAI VIRUS; TRANSFECTION;

EID: 33748428906     PISSN: 01790358     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00383-006-1727-3     Document Type: Article

References (37)

1. Fuchs J, Rydzynski J, von Schweinitz D et al (2002) Pretreatment prognostic factors and treatment results in children with hepatoblastoma - a report from the German Cooperative Pediatric Liver Tumor Study HB 94. Cancer 95:172-182
2. Brown J, Perilongo G, Shafford E et al (2000) Pretreatment prognostic factors for children with hepatoblastoma - results from the International Society of Paediatric Oncology (SIOP) study SIOPEL 1. Eur J Cancer 36:1418-1425
3. Ortega JA, Douglass EC, Feusner JH et al (2000) Randomized comparison of cisplatin/vincristine/flourouracil and cisplatin/continuous infusion doxorubicin for treatment of pediatric hepatoblastoma: a report from the Children's Cancer Group and the Pediatric Oncology Group. J Clin Oncol 18:2665-2675
4. Von Schweinitz D, Byrd DJ, Hecker H, Weinel P, Bode U, Burger D, Erttmann R, Harms D, Mildenberger H (1997) Efficiency and toxicity of ifosfamide, cisplatin and doxorubicin in the treatment of childhood hepatoblastoma. Study Committee of the Cooperative Paediatric Liver Tumour Study HB89 of the German Society for Paediatric Oncology and Haematology. Eur J Cancer 33:1243-1249
5. Minemura M, Tanimura H, Tabor E (1999) Overexpression of multidrug resistance genes MDR1 and cMOAT in human hepatocellular carcinoma and hepatoblastoma cell lines. Int J Oncol 15:559-563
6. Bader P, Fuchs J, Wenderoth M et al (1998) Altered expression of resistance associated genes in hepatoblastoma xenografts incorporated into mice following treatment with doxorubicin or cisplatin. Anticancer Res 18:3127-3132
7. Warmann S, Göhring G, Teichmann B et al (2003) P-glycoprotein modulation improves in vitro chemosensitivity in malignant pediatric liver tumors. Anticancer Res 23:4607-4612
8. Warmann S, Hunger M, Teichmann B et al (2002) The role of the MDR1 gene in the development of multidrug resistance in human hepatoblastoma - clinical course and in vivo model. Cancer 95:1795-1801
9. Mullen JT, Tanabe KK (2003) New approaches to the treatment of hepatic malignancies - viral oncolysis for malignant liver tumors. Ann Surg Oncol 10:569-605
10. Wang L, Hernández-Alcoceba R, Shankar V et al (2004) Prolonged and inducible transgene expression in the liver using gutless adenovirus: a potential therapy for liver cancer. Gastroenterology 126:278-289
11. Benihoud K, Yeh P, Perricaudet M (1999) Adenovirus vectors for gene delivery. Curr Opin Biotechnol 10:440-447
12. Wilson JM (2001) Adenovirus-mediated gene transfer to liver. Adv Drug Deliv Rev 46:205-209
13. Bitzer M, Armeanu S, Lauer UM, Neubert WJ (2003) Sendai virus vectors as an emerging negative-strand viral vector system. J Gene Med 5:543-553
14. Kaneda Y, Nakajima T, Nishikawa T et al (2002) Hemagglutinating virus of Japan (HVJ) envelope vector as a versatile gene delivery system. Mol Ther 6:219-226
15. Adachi Y, Reynolds PN, Yamamoto M et al (2000) Midkine promoter-based adenoviral vector gene delivery for pediatric solid tumors. Cancer Res 60:4305-4310
16. Lemken ML, Wybranietz WA, Schmidt U, Graepler F, Armeanu S, Bitzer M, Lauer UM (2005) Liver-directed gene expression employing synthetic transcriptional control units. World J Gastroenterol 11:5295-5302
17. Pietsch T, Fonatsch C, Albrecht S et al (1996) Characterization of the continuous cell line HepT1 derived from a human hepatoblastoma. Lab Invest 4:809-818
18. Doi I (1976) Establishment of a cell line and its clonal sublines from a patient with hepatoblastoma. Gann 67:1-10
19. Kekule AS, Lauer U, Weiss L, Luber B, Hofschneider PH (1993) Hepatitis B virus transactivator HBx uses a tumour promoter signalling pathway. Nature 361:742-745
20. Wybranietz WA, Gross CD, Phelan A, O'Hare P, Spiegel M, Graepler F, Bitzer M, Stahler P, Gregor M, Lauer UM (2001) Enhanced suicide gene effect by adenoviral transduction of a VP22-cytosine deaminase (CD) fusion gene. Gene Ther 8:1654-1664
21. Leyrer S, Neubert WJ, Sedlmeier R (1998) Rapid and efficient recovery of Sendai virus from cDNA: factors influencing recombinant virus rescue. J Virol Methods 75:47-58
22. Bitzer M, Prinz F, Bauer M, Spiegel M, Neubert WJ, Gregor M, Schulze-Osthoff K, Lauer UM (1999) Sendai virus infection induces apoptosis through activation of caspase-8 (FLICE) and caspase-3 (CPP32). J Virol 73:702-708
23. Han J, Il Yeom Y (2000) Specific gene transfer mediated by galactosylated poly-L-lysine into hepatoma cells. Int J Pharm 202:151-160
24. Aramaki Y, Lee I, Arima H et al (2003) Efficient gene transfer to hepatoblastoma cells through asialoglycoprotein receptor and expression under the control of the glycin A promoter. Biol Pharm Bull 26:357-360
25. Aden D, Fogel A, Plotkin S et al (1979) Controlled synthesis of HbsAg in a differentiated human liver carcinoma-derived cell line. Nature 282:615-617
26. Warmann S, Armeanu S, Frank H, Buck H, Graepler F, Lemken ML, Heitmann H, Seitz G, Lauer UM, Bitzer M, Fuchs J (2006) In vitro gene targeting in human Hepatoblastoma. Pediatr Surg Int 22:16-23
27. Warmann SW, Fuchs J, Seitz G, Ruck P, Treuner C, Mahrt J, Muller GA, Wessels JT (2005) New trends in tumor biology: transfection of a human hepatoblastoma cell line with green fluorescent protein. J Pediatr Surg 40:653-657
28. Gray SG, Hartmann W, Eriksson T et al (2000) Expression of genes involved with cell cycle control, cell growth and chromatin modification are altered in hepatoblastomas. Int J Mol Med 6:161-169
29. Schmitz V, Wang L, Barajas M, Gomar C, Prieto J, Qian C (2004) Treatment of colorectal and hepatocellular carcinomas by adenoviral mediated gene transfer of endostatin and angiostatin-like molecule in mice. Gut 53:561-567
30. Armeanu S, Lauer UM, Smirnow I, Schenk M, Weiss TS, Gregor M, Bitzer M (2003) Adenoviral gene transfer of tumor necrosis factor-related apoptosis-inducing ligand overcomes an impaired response of hepatoma cells but causes severe apoptosis in primary human hepatocytes. Cancer Res 63:2369-2372
31. Pei Z, Chu L, Zou W, Zhang Z, Qiu S, Qi R, Gu J, Qian C, Liu X (2004) An oncolytic adenoviral vector of Smac increases antitumor activity of TRAIL against HCC in human cells and in mice. Hepatology 39:1371-1381
32. Taki M, Kagawa S, Nishizaki M, Mizuguchi H, Hayakawa T, Kyo S, Nagai K, Urata Y, Tanaka N, Fujiwara T (2005) Enhanced oncolysis by a tropism-modified telomerase-specific replication-selective adenoviral agent OBP-405 ('Telomelysin-RGD'). Oncogene 24:3130-3140
33. Li GC, Yang JM, Nie MM, Su CG, Sun LC, Qian YZ, Fang GE, Sham J, Wu MC, Qian QJ (2005) Potent antitumoral effects of a novel gene-viral therapeutic system CNHK300-mEndostatin in hepatocellular carcinoma. Chin Med J (Engl) 118:179-185
34. Staba MJ, Mauceri HJ, Kufe DW et al (1998) Adenoviral TNF-α gene therapy and radiation damage tumor vasculature in a human malignant glioma xenograft. Gene Ther 5:293-300
35. Dilley J, Reddy S, Ko D, Nguyen N, Rojas G, Working P, Yu DC (2005) Oncolytic adenovirus CG7870 in combination with radiation demonstrates synergistic enhancements of antitumor efficacy without loss of specificity. Cancer Gene Ther 12:715-722
36. Armeanu S, Ungerechts G, Bernloehr C, Bossow S, Gregor M, Neubert WJ, Lauer UM, Bitzer M (2003) Cell cycle independent infection and gene transfer by recombinant sendai viruses. J Virol Methods 108:229-233
37. Nakaya H, Ishizu A, Ikeda H et al (2003) In vitro model of suicide gene therapy for alpha-fetoprotein-producing gastric cancer. Anticancer Res 23:3795-3800