Aromatase distribution and regulation in fish

Fish Physiology and Biochemistry

Volumn 31, Issue 2-3, 2005, Pages 215-226

  Piferrer, Francesc ^a   Blázquez, Mercedes ^a  

^a INSTITUT DE CIÈNCIES DEL MAR   (Spain)

Author keywords

cyp19; Endocrine disruptors; Estradiol 17 ; Estrogen; Fish; P450 aromatase; Sex differentiation; Sex steroid receptors; Sex steroids

Indexed keywords

ANDROGEN; AROMATASE; ENDOCRINE DISRUPTOR; ESTROGEN; FAT; GENE PRODUCT; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; ISOENZYME; MESSENGER RNA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; RETINOID X RECEPTOR ALPHA; SEX HORMONE; STEROID RECEPTOR; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR GATA 2; TRANSCRIPTION FACTOR GATA 4;

AROMATIZATION; BRAIN; CATALYSIS; CONFERENCE PAPER; DNA RESPONSIVE ELEMENT; ENVIRONMENTAL FACTOR; ENZYME ACTIVITY; ENZYME LOCALIZATION; ENZYME PHOSPHORYLATION; ESTROGEN SYNTHESIS; FISH; GENE CONTROL; GENE EXPRESSION; GENETIC CODE; GENOME; GONAD; HORMONE ACTION; HYPOPHYSIS; KIDNEY; LIVER; MICHAELIS CONSTANT; NERVOUS SYSTEM DEVELOPMENT; PROMOTER REGION; PROTEIN EXPRESSION; REPRODUCTION; RETINA; SEX DIFFERENTIATION; SOCIAL INTERACTION; TELEOST; TEMPERATURE DEPENDENCE; TESTIS;

TELEOSTEI; TETRAPODA;

EID: 33748414351     PISSN: 09201742     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10695-006-0027-0     Document Type: Conference Paper

References (88)

1. Andersson E, Borg B, Lambert JG (1988) Aromatase activity in brain and pituitary of immature and mature Atlantic salmon (Salmo salar L.) parr. Gen Comp Endocrinol 72:394-401
2. Balthazart J, Baillien M, Ball GF (2001) Phosphorylation processes mediate rapid changes of brain aromatase activity. J Steroid Biochem Mol Biol 79:261-277
3. Blázquez M, Zanuy S, Carrillo M, Piferrer F (1998) Effects of rearing temperature on sex differentiation in the European sea bass (Dicentrarchus labrax L.). J Exp Zool 281:207-216
4. Blázquez M, Piferrer F (2004) Cloning, sequence analysis, tissue distribution, and sex-specific expression of the neural form of P450 aromatase in juvenile sea bass (Dicentrarchus labrax). Mol Cell Endocrinol 219:83-94
5. Borg B (1994) Androgens in teleost fishes. Comp Physiol Biochem C 109:214-245
6. Borg B, Timmers RJ, Lambert JG (1987) Aromatase activity in the brain of the three-spined stickleback, Gasterosteus aculeatus. I. Distribution and effects of season and photoperiod. Exp Biol 47:63-68
7. Callard GV, Petro Z, Ryan KJ (1978) Phylogenetic distribution of aromatase and other androgen converting enzymes in the central nervous system. Endocrinology 103:2283-2290
8. Callard GV, Specker JL, Knapp J, Nishioka RS, Bern HA (1988) Aromatase is concentrated in the proximal pars distalis of tilapia pituitary. Gen Comp Endocrinol 71:70-79
9. Callard GV, Tchoudakova AV, Kishida M, Wood E (2001) Differential tissue distribution, developmental programming, estrogen regulation and promoter characteristics of cyp19 genes in teleost fish. J Steroid Biochem Mol Biol 7:305-314
10. Chang X, Kobayashi T, Senthilkumaran B, Kobayashi-Kajura H, Sudhakumari CC, Nagahama Y (2005) Two types of aromatase with different encoding genes, tissue distribution and developmental expression in Nile tilapia (Oreochromis niloticus). Gen Comp Endocrinol 141:101-115
11. Chang XT, Kobayashi T, Kajiura H, Nakamura M, Nagahama Y (1997) Isolation and characterization of the cDNA encoding the tilapia (Oreochromis niloticus) cytochrome P450 aromatase (P450arom): Changes in P450arom mRNA, protein and enzyme activity in ovarian follicles during oogenesis. J Mol Endocrinol 18:57-66
12. Chiang EF, Yan YL, Guiguen Y, Postlethwait J, Chung B (2001) Two Cyp19 (P450 aromatase) genes on duplicated zebrafish chromosomes are expressed in ovary or brain. Mol Biol Evol 18:542-550
13. Choi JY, Park JG, Jeong HB, Lee YD, Takemura A, Kim SJ (2005) Molecular cloning of cytochrome P450 aromatases in the protogynous wrasse, Halichoeres tenuispinis. Comp Biochem Physiol B 141:49-59
14. Colborn T, vom Saal FS, Soto AM (1993) Developmental effects of endocrine-disrupting chemicals in wildlife and humans. Environ Health Perspect 101:378-384
15. Dalla Valle L, Ramina A, Vianello S, Belvedere P, Colombo L (2002a) Cloning of two mRNA variants of brain aromatase cytochrome P450 in rainbow trout (Oncorhynchus mykiss Walbaum). J Steroid Biochem Mol Biol 82:19-32
16. Dalla Valle L, Lunardi L, Colombo L, Belvedere P (2002b) European sea bass (Dicentrarchus labrax L.) cytochrome P450arom: CDNA cloning, expression and genomic organization. J Steroid Biochem Mol Biol 80:25-34
17. D'Cotta H, Fostier A, Guiguen Y, Govoroun M, Baroiller JF (2001) Aromatase plays a key role during normal and temperature-induced sex differentiation of tilapia Oreochromis niloticus. Mol Reprod Dev 59:265-276
18. de Leeuw R, Smit-van Dijk W, Zigterman JW, van der Loo JC, Lambert JG, Goos HJ (1985) Aromatase, estrogen 2-hydroxylase, and catechol-O-methyltransferase activity in isolated, cultured gonadotropic cells of mature African catfish, Clarias gariepinus (Burchell). Gen Comp Endocrinol 60:171-177
19. Devlin RH, Nagahama Y (2002) Sex determination and sex differentiation in fish: An overview of genetic, physiological, and environmental influences. Aquaculture 208:191-364
20. Forlano PM, Deitcher DL, Myers DA, Bass AH (2001) Anatomical distribution and cellular basis for high levels of aromatase activity in the brain of teleost fish: Aromatase enzyme and mRNA expression identify glia as source. J Neurosci 21:8943-8955
21. Galay-Burgos M, Gealy C, Navarro-Martín L, Piferrer F, Zanuy S, Sweeney GE (2006) Cloning of the promoter from the gonadal aromatase gene of the European sea bass and identification of single nucleotide polymorphisms. Comp Biochem Physiol C (submitted)
22. Gardner L, Anderson T, Place AR, Dixon B, Elizur A (2005) Sex change strategy and the aromatase genes. J Steroid Biochem Mol Biol 94:395-404
23. Gelinas D, Callard GV (1993) Immunocytochemical and biochemical evidence for aromatase in neurons of the retina, optic tectum and retinotectal pathways in goldfish. J Neuroendocrinol 5:635-641
24. Gen K, Okuzawa K, Kumakura N, Yamaguchi S, Kagawa H (2001) Correlation between messenger RNA expression of cytochrome P450 aromatase and its enzyme activity during oocyte development in the red seabream (Pagrus major). Biol Reprod 65:1186-1194
25. González A, Piferrer F (2002) Characterization of aromatase activity in the sea bass: Effects of temperature and different catalytic properties of brain and ovarian homogenates and microsomes. J Exp Zool 293:500-510
26. González A, Piferrer F (2003) Aromatase activity in the European sea bass (Dicentrarchus labrax) brain. Distribution and changes in relation to age, sex, and the annual reproductive cycle. Gen Comp Endocrinol 132:223-230
27. Greytak SR, Champlin D, Callard GV (2005) Isolation and characterization of two cytochrome P450 aromatase forms in killifish (Fundulus heteroclitus): Differential expression in fish from polluted and unpolluted environments. Aquat Toxicol 71:371-389
28. Guiguen Y, Baroiller JF, Ricordel MJ, Iseki K, Mcmeel OM, Martin SA, Fostier A (1999) Involvement of estrogens in the process of sex differentiation in two fish species: The rainbow trout (Oncorhynchus mykiss) and a Tilapia (Oreochromis niloticus). Mol Reprod Develop 54:154-162
29. Harada N, Utsumi T, Takagi Y (1993) Tissue-specific expression of the human aromatase cytochrome P-450 gene by alternate use of multiple exons 1 and promoter, and switching of tissue-specific exons 1 in carcinogenesis. Proc Natl Acad Sci USA 90:11312-11316
30. Ijiri S, Berard C, Trant JM (2000) Characterization of gonadal and extra-gonadal forms of the cDNA encoding the Atlantic stingray (Dasyatis sabina) cytochrome P450 aromatase (CYP19). Mol Cell Endocrinol 164:169-181
31. Ijiri S, Kazeto Y, Lokman PM, Adachi S, Yamauchi K (2003) Characterization of a cDNA encoding P-450 aromatase (CYP19) from Japanese eel ovary and its expression in ovarian follicles during induced ovarian development. Gen Comp Endocrinol 130:193-203
32. Ing NH (2005) Steroid hormones regulate gene expression posttranscriptionally by altering the stabilities of messenger RNAs. Biol Reprod 72:1290-1296
33. Ing NH, O'Malley BW (1995) The steroid hormone receptor superfamily: molecular mechanisms of action. In: Weintraub B (ed) Molecular endocrinology: Basic concepts and clinical correlations. Raven Press, New York, pp 195-216
34. Ing NH, Spencer TE, Bazer FW (1996) Estrogen enhances endometrial estrogen receptor gene expression by a posttranscriptional mechanism in the ovariectomized ewe. Biol Reprod 54:591-599
35. Jeng SR, Dufour S, Chang CF (2005) Differential expression of neural and gonadal aromatase enzymatic activities in relation to gonadal development in Japanese eel, Anguilla japonica. J Exp Zool A Comp Exp Biol 303:802-812
36. Jones ME, Thorburn AW, Britt KL, Hewitt KN, Wreford NG, Proietto J, Oz OK, Leury BJ, Robertson KM, Yao S, Simpson ER (2000) Aromatase-deficient (ArKO) mice have a phenotype of increased adiposity. Proc Natl Acad Sci USA 97:12735-12740
37. Kazeto Y, Trant JM (2005) Molecular biology of channel catfish brain cytochrome P450 aromatase (CYP19A2): Cloning, preovulatory induction of gene expression, hormonal gene regulation and analysis of promoter region. J Mol Endocrinol 35:571-583
38. Kazeto Y, Ijiri S, Place AR, Zohar Y, Trant JM (2001) The 5′-flanking regions of CYP19 A1 and CYP19 A2 in zebrafish. Biochem Biophys Res Commun 288:503-508
39. Kazeto Y, Place AR, Trant JM (2004) Effects of endocrine disrupting chemicals on the expression of CYP19 genes in zebrafish (Danio rerio) juveniles. Aquat Toxicol 69:25-34
40. Kishida M, Callard GV (2001) Distinct cytochrome P450 aromatase isoforms in zebrafish (Danio rerio) brain and ovary are differentially programmed and estrogen regulated during early development. Endocrinology 142:740-750
41. Kitano T, Takamune K, Kobayashi T, Nagahama Y, Abe SI (1999) Suppression of P450 aromatase gene expression in sex-reversed males produced by rearing genetically female larvae at a high water temperature during a period of sex differentiation in the Japanese flounder (Paralichthys olivaceus). J Mol Endocrinol 23:167-176
42. Kitano T, Takamune K, Nagahama Y, Abe SI (2000) Aromatase inhibitor and 17alpha-methyltestosterone cause sex-reversal from genetical females to phenotypic males and suppression of P450 aromatase gene expression in Japanese flounder (Paralichthys olivaceus). Mol Reprod Devel 56:1-5
43. Kobayashi T, Matsuda M, Kajiura-Kobayashi H, Suzuki A, Saito N, Nakamoto M, Shibata N, Nagahama Y (2004a) Two DM domain genes, DMY and DMRT1, involved in testicular differentiation and development in the medaka, Oryzias latipes. Dev Dyn 231:518-526
44. Kobayashi Y, Kobayashi T, Nakamura M, Sunobe T, Morrey CE, Suzuki N, Nagahama Y (2004b) Characterization of two types of cytochrome P450 aromatase in the serial-sex changing gobiid fish, Trimma okinawae. Zool Sci 21:417-425
45. Kroon FJ, Munday PL, Westcott DA, Hobbs JP, Liley NR (2005) Aromatase pathway mediates sex change in each direction. Proc R Soc B 272:1399-1405
46. Kuhl AJ, Manning S, Brouwer M (2005) Brain aromatase in Japanese medaka (Oryzias latipes): Molecular characterization and role in xenoestrogen-induced sex reversal. J Steroid Biochem Mol Biol 96:67-77
47. Kwon JY, McAndrew BJ, Penman DJ (2001) Cloning of brain aromatase gene and expression of brain and ovarian aromatase genes during sexual differentiation in genetic male and female Nile tilapia Oreochromis niloticus. Mol Reprod Dev 59:359-370
48. Kwon JY, Haghpanah V, Kogson-Hurtado LM, McAndrew BJ, Penman DJ (2000) Masculinization of genetic female Nile tilapia (Oreochromis niloticus) by dietary administration of an aromatase inhibitor during sexual differentiation. J Exp Zool 287:46-53
49. Lee YH, Lee FY, Yueh WS, Tacon P, Du JL, Chang CN, Jeng SR, Tanaka H, Chang CF (2000) Profiles of gonadal development, sex steroids, aromatase activity, and gonadotropin II in the controlled sex change of protandrous black porgy, Acanthopagrus schlegeli Bleeker. Gen Comp Endocrinol 119:111-120
50. Luckenbach JA, Early LW, Rowe AH, Borski RJ, Daniels HV, Godwin J (2005) Aromatase cytochrome P450: Cloning, intron variation, and ontogeny of gene expression in southern flounder (Paralichthys lethostigma). J Exp Zool 303A:643-656
51. Martin CC, McGowan R (1995) Genotype-specific modifiers of transgene methylation and expression in the zebrafish, Danio rerio. Genet Res 65:21-28
52. Mayer I, Borg B, Berglund I, Lambert JG (1991) Effects of castration and androgen treatment on aromatase activity in the brain of mature male Atlantic salmon (Salmo salar L.) parr. Gen Comp Endocrinol 82:86-92
53. Melo AC, Ramsdell JS (2001) Sexual dimorphism of brain aromatase activity in medaka: Induction of a female phenotype by estradiol. Environ Health Perspect 109:257-264
54. Menuet A, Pellegrini E, Brion F, Gueguen MM, Anglade I, Pakdel F, Kah O (2005) Expression and estrogen-dependent regulation of the zebrafish brain aromatase gene. J Comp Neurol 485:304-320
55. Meyet A, Schartl M (1999) Gene and genome duplications in vertebrates: the one-to-four (-to-eight in fish) rule and the evolution of novel gene functions Curr Opin Cell Biol 11:699-704
56. Montserrat N, González A, Méndez E, Piferrer F, Planas JV (2004) Effects of follicle stimulating hormone on estradiol-17 beta production and P-450 aromatase (CYP19) activity and mRNA expression in brown trout vitellogenic ovarian follicles in vitro. Gen Comp Endocrinol 137:123-131
57. Murdock C, Wibbels T (2003) Cloning and expression of aromatase in a turtle with temperature-dependent sex determination. Gen Comp Endocrinol 130:109-119
58. Nakamura M, Kobayashi T, Chang XT, Nagahama Y (1998) Gonadal sex differentiation in teleost fish. J Exp Zool 281:362-372
59. Nes SV, Moe M, Andersen O (2005) Molecular characterization and expression of two cyp19 (P450 aromatase) genes in embryos, larvae and adults of Atlantic halibut (Hippoglossus hippoglossus). Mol Reprod Develop 72:437-449
60. Olivereau M, Callard G (1985) Distribution of cell types and aromatase activity in the sculpin (Myoxocephalus) pituitary. Gen Comp Endocrinol 58:280-290
61. Orlando EF, Davis WP, Guillette LJ (2002) Aromatase activity in the ovary and brain of the eastern mosquitofish (Gambusia holbrooki) exposed to paper mill effluent. Environ Health Perspect 110(suppl 3):429-433
62. Pasmanik M, Callard GV (1985) Aromatase and 5-alpha-reductase in the teleost brain, spinal cord, and pituitary gland. Gen Comp Endocrinol 60:244-251
63. Pellegrini E, Menuet A, Lethimonier C, Adrio F, Gueguen MM, Tascon C, Anglade I, Pakdel F, Kah O (2005) Relationships between aromatase and estrogen receptors in the brain of teleost fish. Gen Comp Endocrinol 142:60-66
64. Perry AN, Grober MS (2003) A model for social control of sex change: interactions of behavior, neuropeptides, glucocorticoids, and sex steroids. Horm Behav 43:31-38
65. Piferrer F, Zanuy S, Carrillo M, Solar II, Devlin RH, Donaldson EM (1994a) Brief treatment with an aromatase inhibitor during sex differentiation causes chromosomally female salmon to develop as normal, functional males. J Exp Zool 270:255-262
66. Piferrer F, Carrillo M, Zanuy S, Solar II, Donaldson EM (1994b) Induction of sterility in coho salmon, (Oncorhynchus kisutch), by androgen immersion before first feeding. Aquaculture 119:409-423
67. Price T, Aitken J, Simpson ER (1992) Relative expression of aromatase cytochrome P450 in human fetal tissues as determined by competitive polymerase chain reaction amplification. J Clin Endocrinol Metab 74:879-883
68. Price TM, O'Brien SN (1993) Determination of estrogen receptor messenger ribonucleic acid (mRNA) and cytochrome P450 aromatase mRNA levels in adipocytes and adipose stromal cells by competitive polymerase chain reaction amplification. J Clin Endocrinol Metab 77:1041-1045
69. Simpson ER, Clyne C, Rubin G, Boon WC, Robrtson K, Britt K, Speed C, Jones M (2002) Aromatase - a brief overview. Annu Rev Physiol 64:93-127
70. Strobl-Mazzulla PH, López GC, Miranda LA, Somoza GM (2003) Neuroanatomical distribution and partial sequence of cDNA encoding brain cytochrome P450 aromatase (P450aromB) in pejerrey Odontesthes bonariensis. Fish Physiol Biochem 28:51-52
71. Strobl-Mazzulla PH, Moncaut NP, López GC, Miranda LA, Canario AV, Somoza GM (2005) Brain aromatase from pejerrey fish (Odontesthes bonariensis): CDNA cloning, tissue expression, and immunohistochemical localization. Gen Comp Endocrinol 143:21-32
72. Sunobe T, Nakamura M, Kobayashi Y, Kobayashi T, Nagahama Y (2005) Aromatase immunoreactivity and the role of enzymes in steroid pathways for inducing sex change in the hermaphrodite gobiid fish Trimma okinawae. Comp Biochem Physiol Part A 141:54-59
73. Suzuki A, Tanaka M, Shibata N (2004) Expression of aromatase mRNA and effects of aromatase inhibitor during ovarian development in the medaka, Oryzias latipes. J Exp Zool 301A:266-273
74. Tanaka M, Fudaka S, Matsuyama M, Nagahama Y (1995) Structure and promoter analysis of the cytochrome P-450 aromatase gene of the teleost fish, medaka (Oryzias latipes). J Biochem (Tokyo) 117:719-725
75. Tchoudakova A, Callard GV (1998) Identification of multiple CYP19 genes encoding different cytochrome P450 aromatase isozymes in brain and ovary. Endocrinology 139:2179-2189
76. Tchoudakova A, Kishida M, Wood E, Callard GV (2001) Promoter characterisation of two cyp19 genes differentially expressed in the brain and ovary of teleost fish. J Steroid Biochem Mol Biol 78:427-439
77. Timmers RJ, Lambert JG, Peute J, Vullings HG, van Oordt PG (1987) Localization of aromatase in the brain of the male African catfish, Clarias gariepinus (Burchell), by microdissection and biochemical identification. J Comp Neurol 258:368-377
78. Tong SK, Chung BC (2003) Analysis of zebrafish cyp19 promoters. J Steroid Biochem Mol Biol 86:381-386
79. Trant JM, Lehrter J, Gregory T, Nunez S, Wunder J (1997) Expression of cytochrome P450 aromatase in the channel catfish, Ictalurus punctatus. J Steroid Biochem Mol Biol 61:393-397
80. Tsai CL, Wang LH, Chang CF, Kao CC (2000) Effects of gonadal steroids on brain serotonergic and aromatase activity during the critical period of sexual differentiation in tilapia, Oreochromis mossambicus. J Neuroendocrinol 12:894-898
81. Tsai CL, Chang SL, Wang LH, Chao TY (2003) Temperature influences the ontogenetic expression of aromatase and oestrogen receptor mRNA in the developing tilapia (Oreochromis mossambicus) brain. J Neuroendocrinol 15:97-102
82. Tzchori I, Degani G, Hurvitz A, Moav B (2004) Cloning and developmental expression of the cytochrome P450 aromatase gene (CYP19) in the European eel (Anguilla anguilla). Gen Comp Endocrinol 138:271-280
83. Uchida D, Yamashita M, Kitano T, Iguchi T (2002) Oocyte apoptosis during the transition from ovary-like tissue to testes during sex differentiation of juvenile zebrafish. J Exp Biol 205:711-718
84. Uchida D, Yamashita M, Kitano T, Iguchi T (2004) An aromatase inhibitor or high water temperature induce oocyte apoptosis and depletion of P450 aromatase activity in the gonads of genetic female zebrafish during sex-reversal. Comp Biochem Physiol A 137:11-20
85. Watts M, Pankhurst NW, King HR (2004) Maintenance of Atlantic salmon (Salmo salar) at elevated temperature inhibits cytochrome P450 aromatase activity in isolated ovarian follicles. Gen Comp Endocrinol 135:381-390
86. Yanase T, Mu YM, Nishi Y, Goto K, Nomura M, Okabe T, Takayanagi R, Nawata H (2001) Regulation of aromatase by nuclear receptors. J Steroid Biochem Mol Biol 79:187-192
87. Zhang Y, Zhang W, Zhang L, Zhu T, Tian J, Li X, Lin H (2004) Two distinct cytochrome P450 aromatases in the orange-spotted grouper (Epinephelus coioides): CDNA cloning and differential mRNA expression. J Steroid Biochem Mol Biol 92:39-50
88. Zupanc GKH (2001) Adult neurogenesis and neuronal regeneration in the central nervous system of teleost fish. Brain Behav Evol 58:250-275