A melatonin-rich germplasm line of St John's wort (Hypericum perforatum L.)

Journal of Pineal Research

Volumn 41, Issue 3, 2006, Pages 284-287

  Murch, Susan J ^a   Saxena, Praveen K ^b  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^b UNIVERSITY OF GUELPH   (Canada)

Author keywords

Antioxidant potential; Germplasm; Hypericum perforatum; Melatonin; St John's wort

Indexed keywords

ANTIOXIDANT; FREE RADICAL; INDOLEAMINE; MELATONIN; SCAVENGER;

AGING; ARTICLE; CANCER INHIBITION; CONTROLLED STUDY; DEPRESSION; GENETIC VARIABILITY; GERMPLASM; HYPERICUM PERFORATUM; MEDICINAL PLANT; NONHUMAN; ORGANOGENESIS; PHYTOCHEMISTRY; SLEEP DISORDER;

ANTIOXIDANTS; HYPERICUM; MELATONIN;

EID: 33748362620     PISSN: 07423098     EISSN: 1600079X     Source Type: Journal    
DOI: 10.1111/j.1600-079X.2006.00367.x     Document Type: Article

References (26)

1. DARWIN C. The Power of Movement in Plants. 1880; pp. 546-573.
2. TREWAVAS A. Green plants as intelligent organisms. Trends Plant Sci 2005; 10:413-419.
3. REITER RJ. Oxidative damage in the central nervous system: protection by melatonin. Prog Neurobiol 1998; 56:359-384.
4. REITER RJ, TAN D-X, BURKHARDT S, MANCHESTER LC. Melatonin in plants. Nutr Rev 2001; 59:286-290.
5. MURCH SJ, SAXENA PK. Melatonin: a potential regulator of plant growth and development? In Vitro Cell Dev Biol Plant 2002; 38:531-537.
6. MURCH SJ, SAXENA PK. Mammalian neurohormones: potential significance in sexual and asexual reproduction of St. John's wort (Hypericum perforatum L.)? Naturwissenschaften 2002; 89:555-560.
7. MANCHESTER LC, TAN D-X, REITER RJ et al. High levels of melatonin in the seeds of edible plants - possible function in germ tissue protection. Life Sci 2000; 67:3023-3029.
8. REITER RJ, TAN D-X. Melatonin: an antioxidant in edible plants. Ann NY Acad Sci 2002; 957:341-344.
9. CHEN G, HUO Y, TAN D-X et al. Melatonin in Chinese medicinal herbs. Life Sci 2003; 73: 19-26.
10. REITER RJ. Melatonin in walnuts: influence on levels of melatonin and total antioxidant capacity of blood. Nutrition 2005; 21:920-924.
11. VAN TASSEL DL, O'NEILL SD. Putative regulatory molecules in plants: evaluating melatonin. J Pineal Res 2001; 31:1-7.
12. KOLAR J, MACHACKOVA I. Melatonin in higher plants: occurrence and possible functions. J Pineal Res 2005; 39:333-341.
13. MURCH SJ, SIMMONS CB, SAXENA PK. Melatonin in fever few and other medicinal plants. Lancet 1997; 350:1598-1599.
14. MURCH SJ, KRISHNARAJ S, SAXENA PK. Tryptophan is a precursor for melatonin and serotonin biosynthesis in in vitro regenerated St. John's wort (Hypericum perforatum L. cv. Anthos) plants. Plant Cell Rep 2000; 19:698-704.
15. MURASHIGE T, SKOOG F. A revised medium for rapid growth and bioassays with tobacco tissue cultures. Physiol Plant 1962; 15:473-497.
16. GAMBORG OL, MILLER RA, OJIMA K. Nutrient requirements of suspension cultures of soybean root cells. Exp Cell Res 1968; 50:151-158.
17. TAKAHATA Y, OHNISHI-KAMEYAMA M, FURUATA S et al. Highly polymerized procyanidins in brown soybean seed coat with a high radical-scavenging activity. Int J Agric Food Chem 2001; 49:5843-5847.
18. TAN D-X, REITER RJ. Chemical and physical properties and potential mechanisms: melatonin as a broad spectrum antioxidant and free radical scavenger. Curr Top Med Chem 2002; 2:181-197.
19. BLASK DE, DAUCHY RT, SAUER LA et al. Melatonin uptake and growth prevention in rat hepatoma 7288CTC in response to dietary melatonin: melatonin receptor-mediated inhibition of tumor linoleic acid metabolism to the growth signaling molecule 13-hydroxyoctadecadienoic acid and the potential role of phytomelatonin. Carcinogenesis 2004; 25:951-960.
20. COLASANTI A, KISSLINGER A, LIUZZI R et al. Hypericin photosensitization of tumor and metastatic cell lines of human prostate. J Photochem Photobiol 2000; 29:103-107.
21. BLANK M, MANDEL M, HAZAN S et al. Anti-cancer activities of hypericin in the dark. Photochem Photobiol 2001; 74:120- 125.
22. AGOSTINIS P, VANTIEGHEMA A, MERLEVEDE W et al. Hypericin in cancer treatment: more light on the way. Int J Biochem Cell Biol 2002; 34:221-241.
23. SCHEMPP CM, KIRKIN V, SIMON-HAARHAUS B et al. Inhibition of tumour cell growth by hyperforin, a novel anticancer drug from St. John's wort that acts by induction of apoptosis. Oncogene 2002; 21:1242-1250.
24. MULLER WE. Current St. John's wort research from mode of action to clinical efficacy. Pharmacol Res 2003; 47:101-109.
25. RODRIGUEZ-LANDA JF, CONTRERAS CM. A review of clinical and experimental observations about antidepressant actions and side effects produced by Hypericum perforatum extracts. Phytomedicine 2003; 10:688-699.
26. ROSCETTI G, FRANZESE O, COMANDINI A et al. Cytotoxic activity of Hypericum perforatum L. on K562 erythroleukemic cells: Differential effects between methanolic extract and hypericin. Phytother Res 2004; 18:66-72.