Investigating disease susceptibility and the negative correlation of schizophrenia and rheumatoid arthritis focusing on MIF and CD14 gene polymorphisms

Psychiatry Research

Volumn 144, Issue 1, 2006, Pages 39-47

  de la Fontaine, Larissa ^a   Schwarz, Markus J ^a   Riedel, Michael ^a   Dehning, Sandra ^a   Douhet, Anette ^a   Spellmann, Ilja ^a   Kleindienst, Nikolaus ^c   Zill, Peter ^a   Plischke, Herbert ^b   Gruber, Rudolf ^b   Müller, Norbert ^a  

^a LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

^b UNIVERSITY OF MUNICH   (Germany)

^c CENTRAL INSTITUTE OF MENTAL HEALTH   (Germany)

Author keywords

CATT repeat; Negative association; Polymorphism; SNP; Susceptibility

Indexed keywords

CD14 ANTIGEN; MACROPHAGE MIGRATION INHIBITION FACTOR;

ADULT; AGED; ARTICLE; AUTOIMMUNITY; CAUCASIAN; CHRONIC INFLAMMATION; CONTROLLED STUDY; CORRELATION ANALYSIS; DISEASE ASSOCIATION; DISEASE PREDISPOSITION; DNA POLYMORPHISM; FEMALE; GENE; GENE MUTATION; HEREDITY; HUMAN; MAJOR CLINICAL STUDY; MALE; NUCLEOTIDE REPEAT; PRIORITY JOURNAL; RHEUMATOID ARTHRITIS; SCHIZOPHRENIA; SINGLE NUCLEOTIDE POLYMORPHISM;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; ALLELES; ANTIGENS, CD14; ARTHRITIS, RHEUMATOID; DNA MUTATIONAL ANALYSIS; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HUMANS; INTRAMOLECULAR OXIDOREDUCTASES; MACROPHAGE MIGRATION-INHIBITORY FACTORS; MALE; MICROSATELLITE REPEATS; MIDDLE AGED; POLYMORPHISM, GENETIC; POLYMORPHISM, SINGLE NUCLEOTIDE; SCHIZOPHRENIA; STATISTICS; STATISTICS AS TOPIC;

EID: 33748329372     PISSN: 01651781     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.psychres.2006.01.006     Document Type: Article

References (58)

1. Arnett F.C., Edworthy S.M., Bloch D.A., McShane D.J., Fries J.F., Cooper N.S., Healey L.A., Kaplan S.R., Liang M.H., and Luthra H.S. The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis. Arthritis and Rheumatism 31 (1988) 315-324
2. Arolt V., Rothermundt M., Wandinger K.P., and Kirchner H. Decreased in vitro production of interferon-gamma and interleukin-2 in whole blood of patients with schizophrenia during treatment. Molecular Psychiatry 5 (2000) 150-158
3. Ashcroft G.S., Mills S.J., Lei K., Gibbons L., Jeong M.J., Taniguchi M., Burow M., Horan M.A., Wahl S.M., and Nakayama T. Estrogen modulates cutaneous wound healing by downregulating macrophage migration inhibitory factor. Journal of Clinical Investigation 111 (2003) 1309-1318
4. Bacher M., Metz C.N., Calandra T., Mayer K., Chesney J., Lohoff M., Gemsa D., Donnelly T., and Bucala R. An essential regulatory role for macrophage migration inhibitory factor in T-cell activation. Proceedings of the National Academy of Sciences of the United States of America 93 (1996) 7849-7854
5. Badner J.A., and Gershon E.S. Meta-analysis of whole-genome linkage scans of bipolar disorder and schizophrenia. Molecular Psychiatry 7 (2002) 405-411
6. Baldini M., Lohman I.C., Halonen M., Erickson R.P., Holt P.G., and Martinez F.D. A polymorphism in the 5′ flanking region of the CD14 gene is associated with circulating soluble CD14 levels and with total serum immunoglobulin E. American Journal of Respiratory Cell and Molecular Biology 20 (1999) 976-983
7. Baugh J.A., Chitnis S., Donnelly S.C., Monteiro J., Lin X., Plant B.J., Wolfe F., Gregersen P.K., and Bucala R. A functional promoter polymorphism in the macrophage migration inhibitory factor (MIF) gene associated with disease severity in rheumatoid arthritis. Genes and Immunity 3 (2002) 170-176
8. Borda T., Gomez R., Berria M.I., and Sterin-Borda L. Antibodies against astrocyte M1 and M2 muscarinic cholinoceptor from schizophrenic patients' sera. Glia 45 (2004) 144-154
9. Butts C., and Sternberg E. Different approaches to understanding autoimmune rheumatic diseases: the neuroimmunoendocrine system. Best practice and research. Clinical Rheumatology 18 (2004) 125-139
10. Bynoe M.S., Grimaldi C.M., and Diamond B. Estrogen up-regulates Bcl-2 and blocks tolerance induction of naive B cells. Proceedings of the National Academy of Sciences of the United States of America 97 (2000) 2703-2708
11. Cardno A.G., Marshall E.J., Coid B., Macdonald A.M., Ribchester T.R., Davies N.J., Venturi P., Jones L.A., Lewis S.W., Sham P.C., Gottesman I.I., Farmer A.E., McGuffin P., Reveley A.M., and Murray R.M. Heritability estimates for psychotic disorders: the Maudsley twin psychosis series. Archives of General Psychiatry 56 (1999) 162-168
12. De Benedetti F., Meazza C., Vivarelli M., Rossi F., Pistorio A., Lamb R., Lunt M., Thomson W., Ravelli A., Donn R., and Martini A. Functional and prognostic relevance of the -173 polymorphism of the macrophage migration inhibitory factor gene in systemic-onset juvenile idiopathic arthritis. Arthritis and Rheumatism 48 (2003) 1398-1407
13. Dobrovolskaia M.A., and Vogel S.N. Toll receptors, CD14, and macrophage activation and deactivation by LPS. Microbes and Infection 4 (2002) 903-914
14. Donn R.P., Shelley E., Ollier W.E., and Thomson W. A novel 5′-flanking region polymorphism of macrophage migration inhibitory factor is associated with systemic-onset juvenile idiopathic arthritis. Arthritis and Rheumatism 44 (2001) 1782-1785
15. Eaton W.W., Hayward C., and Ram R. Schizophrenia and rheumatoid arthritis: a review. Schizophrenia Research 6 (1992) 181-192
16. Ganguli R., Yang Z., Shurin G., Chengappa K.N., Brar J.S., Gubbi A.V., and Rabin B.S. Serum interleukin-6 concentration in schizophrenia: elevation associated with duration of illness. Psychiatry Research 51 (1994) 1-10
17. Ganguli R., Brar J.S., Chengappa K.R., DeLeo M., Yang Z.W., Shurin G., and Rabin B.S. Mitogen-stimulated interleukin-2 production in never-medicated, first-episode schizophrenic patients. The influence of age at onset and negative symptoms. Archives of General Psychiatry 52 (1995) 668-672
18. Gorwood P., Pouchot J., Vinceneux P., Puechal X., Flipo R.M., De Bandt M., and Ades J. Rheumatoid arthritis and schizophrenia: a negative association at a dimensional level. Schizophrenia Research 66 (2004) 21-29
19. Hailman E., Lichenstein H.S., Wurfel M.M., Miller D.S., Johnson D.A., Kelley M., Busse L.A., Zukowski M.M., and Wright S.D. Lipopolysaccharide (LPS)-binding protein accelerates the binding of LPS to CD14. Journal of Experimental Medicine 179 (1994) 269-277
20. Halbreich U., and Kahn L.S. Hormonal aspects of schizophrenias: an overview. Psychoneuroendocrinology 28 Suppl 2 (2003) 1-16
21. Hanson D.R., and Gottesman I.I. Theories of schizophrenia: a genetic-inflammatory-vascular synthesis. BMC Medical Genetics 6 (2005) 7
22. Harney S.M., Newton J.L., and Wordsworth B.P. Molecular genetics of rheumatoid arthritis. Current Opinion in Pharmacology 3 (2003) 280-285
23. Heath R.G., McCarron K.L., and O'Neil C.E. Antiseptal brain antibody in IgG of schizophrenic patients. Biological Psychiatry 25 (1989) 725-733
24. Henneberg A.E., Horter S., and Ruffert S. Increased prevalence of antibrain antibodies in the sera from schizophrenic patients. Schizophrenia Research 14 (1994) 15-22
25. Hubacek J.A., Rothe G., Pit'ha J., Skodova Z., Stanek V., Poledne R., and Schmitz G. C(-260)→T polymorphism in the promoter of the CD14 monocyte receptor gene as a risk factor for myocardial infarction. Circulation 99 (1999) 3218-3220
26. Jacobson D.L., Gange S.J., Rose N.R., and Graham N.M. Epidemiology and estimated population burden of selected autoimmune diseases in the United States. Clinical Immunology and Immunopathology 84 (1997) 223-243
27. Jones A.L., Mowry B.J., Pender M.P., and Greer J.M. Immune dysregulation and self-reactivity in schizophrenia: do some cases of schizophrenia have an autoimmune basis?. Immunology and Cell Biology 83 (2005) 9-17
28. Kelly R.H., Ganguli R., and Rabin B.S. Antibody to discrete areas of the brain in normal individuals and patients with schizophrenia. Biological Psychiatry 22 (1987) 1488-1491
29. Koran L.M., Sox Jr. H.C., Marton K.I., Moltzen S., Sox C.H., Kraemer H.C., Imai K., Kelsey T.G., Rose Jr. T.G., and Levin L.C. Medical evaluation of psychiatric patients. I. Results in a state mental health system. Archives of General Psychiatry 46 (1989) 733-740
30. LeVan T.D., Bloom J.W., Bailey T.J., Karp C.L., Halonen M., Martinez F.D., and Vercelli D. A common single nucleotide polymorphism in the CD14 promoter decreases the affinity of Sp protein binding and enhances transcriptional activity. Journal of Immunology 167 (2001) 5838-5844
31. Leweke F.M., Gerth C.W., Koethe D., Klosterkotter J., Ruslanova I., Krivogorsky B., Torrey E.F., and Yolken R.H. Antibodies to infectious agents in individuals with recent onset schizophrenia. European Archives of Psychiatry and Clinical Neuroscience 254 (2004) 4-8
32. Lewis C.M., Levinson D.F., Wise L.H., DeLisi L.E., Straub R.E., Hovatta I., Williams N.M., Schwab S.G., Pulver A.E., Faraone S.V., Brzustowicz L.M., Kaufmann C.A., Garver D.L., Gurling H.M., Lindholm E., Coon H., Moises H.W., Byerley W., Shaw S.H., Mesen A., Sherrington R., O'Neill F.A., Walsh D., Kendler K.S., Ekelund J., Paunio T., Lonnqvist J., Peltonen L., O'Donovan M.C., Owen M.J., Wildenauer D.B., Maier W., Nestadt G., Blouin J.L., Antonarakis S.E., Mowry B.J., Silverman J.M., Crowe R.R., Cloninger C.R., Tsuang M.T., Malaspina D., Harkavy-Friedman J.M., Svrakic D.M., Bassett A.S., Holcomb J., Kalsi G., McQuillin A., Brynjolfson J., Sigmundsson T., Petursson H., Jazin E., Zoega T., and Helgason T. Genome scan meta-analysis of schizophrenia and bipolar disorder, part II: schizophrenia. American Journal of Human Genetics 73 (2003) 34-48
33. Li G., Shen Y.C., Li Y.T., Chen C.H., Zhau Y.W., and Silverman J.M. A case-control study of Alzheimer's disease in China. Neurology 42 (1992) 1481-1488
34. McDowell I. Alzheimer's disease: insights from epidemiology. Aging (Milano) 13 (2001) 143-162
35. Moots R.J., Al-Saffar Z., Hutchinson D., Golding S.P., Young S.P., Bacon P.A., and McLaughlin P.J. Old drug, new tricks: haloperidol inhibits secretion of proinflammatory cytokines. Annals of Rheumatic Diseases 58 (1999) 585-587
36. Morand E.F. New therapeutic target in inflammatory disease: macrophage migration inhibitory factor. Internal Medicine Journal 35 (2005) 419-426
37. Morand E.F., and Leech M. Macrophage migration inhibitory factor in rheumatoid arthritis. Frontiers in Bioscience 10 (2005) 12-22
38. Morand E.F., Leech M., Weedon H., Metz C., Bucala R., and Smith M.D. Macrophage migration inhibitory factor in rheumatoid arthritis: clinical correlations. Rheumatology (Oxford) 41 (2002) 558-562
39. Müller N., Riedel M., Ackenheil M., and Schwarz M.J. Cellular and humoral immune system in schizophrenia: a conceptual re-evaluation. World Journal of Biological Psychiatry 1 (2000) 173-179
40. Müller N., Riedel M., Scheppach C., Brandstätter B., Sokullu S., Krampe K., Ulmschneider M., Möller H.-J., and Schwarz M.J. Beneficial antipsychotic effects of celecoxib add-on therapy compared to risperidone alone in schizophrenia. American Journal of Psychiatry 159 (2002) 1029-1034
41. Mundo E., Altamura A.C., Vismara S., Zanardini R., Bignotti S., Randazzo R., Montresor C., and Gennarelli M. MCP-1 gene (SCYA2) and schizophrenia: a case-control association study. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics 132 (2005) 1-4
42. Oken R.J., and Schulzer M. At issue: schizophrenia and rheumatoid arthritis: the negative association revisited. Schizophrenia Bulletin 25 (1999) 625-638
43. Pearce B.D. Schizophrenia and viral infection during neurodevelopment: a focus on mechanisms. Molecular Psychiatry 6 (2001) 634-646
44. Rubinstein G. Schizophrenia, rheumatoid arthritis and natural resistance genes. Schizophrenia Research 25 (1997) 177-181
45. Schwab S.G., Hallmayer J., Albus M., Lerer B., Eckstein G.N., Borrmann M., Segman R.H., Hanses C., Freymann J., Yakir A., Trixler M., Falkai P., Rietschel M., Maier W., and Wildenauer D.B. A genome-wide autosomal screen for schizophrenia susceptibility loci in 71 families with affected siblings: support for loci on chromosome 10p and 6. Molecular Psychiatry 5 (2000) 638-649
46. Schwab S.G., Mondabon S., Knapp M., Albus M., Hallmayer J., Borrmann-Hassenbach M., Trixler M., Grobeta M., Schulze T.G., Rietschel M., Lerer B., Maier W., and Wildenauer D.B. Association of tumor necrosis factor alpha gene -G308A polymorphism with schizophrenia. Schizophrenia Research 65 (2003) 19-25
47. Schwarz M.J., Chiang S., Müller N., and Ackenheil M. T-helper-1 and T-helper-2 responses in psychiatric disorders. Brain, Behavior, and Immunity 15 (2001) 340-370
48. Schwarz M.J., Kronig H., Riedel M., Dehning S., Douhet A., Spellmann I., Ackenheil M., Möller H.J., and Müller N. IL-2 and IL-4 polymorphisms as candidate genes in schizophrenia. European Archives of Psychiatry and Clinical Neuroscience 256 (2006) 72-76
49. Silman A.J., and Pearson J.E. Epidemiology and genetics of rheumatoid arthritis. Arthritis Research 4 Suppl 3 (2002) S265-S272
50. Spector T.D., and Silman A.J. Rheumatoid arthritis, diabetes, and schizophrenia. Lancet 335 (1990) 228-229
51. Torrey E.F., and Yolken R.H. The schizophrenia-rheumatoid arthritis connection: infectious, immune, or both?. Brain, Behavior, and Immunity 15 (2001) 401-410
52. Vinogradov S., Gottesman I.I., Moises H.W., and Nicol S. Negative association between schizophrenia and rheumatoid arthritis. Schizophrenia Bulletin 17 (1991) 669-678
53. Wordsworth P. Rheumatoid arthritis. Current Opinion in Immunology 4 (1992) 766-769
54. Wordsworth B.P., and Bell J.I. The immunogenetics of rheumatoid arthritis. Springer Seminars in Immunopathology 14 (1992) 59-78
55. Wright S.D., Ramos R.A., Tobias P.S., Ulevitch R.J., and Mathison J.C. CD14, a receptor for complexes of lipopolysaccharide (LPS) and LPS binding protein. Science 249 (1990) 1431-1433
56. Yolken R. Viruses and schizophrenia: a focus on herpes simplex virus. Herpes 11 Suppl 2 (2004) 83A-88A
57. Yu S., Nakashima N., Xu B.H., Matsuda T., Izumihara A., Sunahara N., Nakamura T., Tsukano M., and Matsuyama T. Pathological significance of elevated soluble CD14 production in rheumatoid arthritis: in the presence of soluble CD14, lipopolysaccharides at low concentrations activate RA synovial fibroblasts. Rheumatology International 17 (1998) 237-243
58. Zorrilla E.P., Cannon T.D., Gur R.E., and Kessler J. Leukocytes and organ-nonspecific autoantibodies in schizophrenics and their siblings: markers of vulnerability or disease?. Biological Psychiatry 40 (1996) 825-833