Analytical interference of hydroxyurea in the determination of urea, uric acid, and lactic acid

Analytical Biochemistry

Volumn 357, Issue 1, 2006, Pages 147-149

  Restituto, P ^a   Mugueta, C ^a   Alegre, E ^a   Monreal, J I ^a   Varo, N ^a  

^a UNIVERSITY CLINIC OF NAVARRA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

LACTIC ACID;

HYDROXYUREA; URIC ACIDS;

UREA;

ALLANTOIN; AMINOPHENAZONE; HYDROGEN PEROXIDE; HYDROXYLAMINE; HYDROXYUREA; LACTATE 2 MONOOXYGENASE; LACTIC ACID; PEROXIDASE; SULFONIC ACID DERIVATIVE; URATE OXIDASE; UREA; URIC ACID;

ARTICLE; CHEMICAL ANALYSIS; CLINICAL ARTICLE; CONTROLLED STUDY; DNA DAMAGE; DNA SYNTHESIS INHIBITION; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG CYTOTOXICITY; DRUG METABOLISM; DRUG SOLUBILITY; FALSE POSITIVE RESULT; HUMAN; HUMAN TISSUE; LACTATE BLOOD LEVEL; MOLECULAR WEIGHT; PRIORITY JOURNAL; PURINE METABOLISM; REFERENCE VALUE; STATISTICAL ANALYSIS; UREA BLOOD LEVEL; URIC ACID BLOOD LEVEL;

EID: 33748314865     PISSN: 00032697     EISSN: 10960309     Source Type: Journal    
DOI: 10.1016/j.ab.2006.06.015     Document Type: Article

References (13)

1. Opacic N., Zorc B., Cetina M., Mrvos-Sermek D., Raic-Malic S., and Mintas M. Synthesis and X-ray crystal structure study of the hydroxyurea and hydantoin derivatives of l-valine. J. Peptide Res. 66 (2005) 85-93
2. Cole D.R., Beckloff G.L., and Rousselot L.M. Clinical results with hydroxyurea in cancer chemotherapy: preliminary report. N. Y. State J. Med. 65 (1965) 2132-2136
3. Voskaridou E., Terpos E., Komninaka V., Eftyhiadis E., Mantzourani M., and Loukopoulos D. Chronic myeloid leukaemia with marked thrombocytosis in a patient with thalassaemia major: complete haematological remission under the combination of hydroxyurea and anagrelide. Br. J. Haematol. 116 (2002) 155-157
4. Gach J.E., and Berth-Jones J. Successful treatment of recalcitrant psoriasis with a combination of infliximab and hydroxyurea. J. Dermatol. Treat. 14 (2003) 226-228
5. Italian researcher continues to focus on hydroxyurea treatment for HIV, AIDS Alert 20 (2005) 116-117.
6. Yarbro J.W., Kennedy B.J., and Barnum C.P. Hydroxyurea inhibition of DNA synthesis in ascites tumor. Proc. Natl. Acad. Sci. USA 53 (1965) 1033-1035
7. Yarbro J.W. Mechanism of action of hydroxyurea. Semin. Oncol. 19 (1992) 1-10
8. Yarbro J.W. Further studies on the mechanism of action of hydroxyurea. Cancer Res. 28 (1968) 1082-1087
9. Rodriguez G.I., Kuhn J.G., Weiss G.R., Hilsenbeck S.G., Eckardt J.R., Thurman A., Rinaldi D.A., Hodges S., Von Hoff D.D., and Rowinsky E.K. A bioavailability and pharmacokinetic study of oral and intravenous hydroxyurea. Blood 91 (1998) 1533-1541
10. Andrae U. Evidence for the involvement of cytochrome P-450-dependent monooxygenase(s) in the formation of genotoxic metabolites from N-hydroxyurea. Biochem. Biophys. Res. Commun. 118 (1984) 409-415
11. King S.B. N-Hydroxyurea and acyl nitroso compounds as nitroxyl (HNO) and nitric oxide (NO) donors. Curr. Top. Med. Chem. 5 (2005) 665-673
12. Timson J. Hydroxyurea. Mutat. Res. 32 (1975) 115-132
13. Sakano K., Oikawa S., Hasegawa K., and Kawanishi S. Hydroxyurea induces site-specific DNA damage via formation of hydrogen peroxide and nitric oxide. Jpn. J. Cancer Res. 92 (2001) 1166-1174