Histopathological comparison of topical therapy modalities for acute radiation proctitis in an experimental rat model

World Journal of Gastroenterology

Volumn 12, Issue 30, 2006, Pages 4879-4883

  Korkut, Cagatay ^a   Asoglu, Oktar ^b   Aksoy, Murat ^b   Kapran, Yersu ^b   Bilge, Hatice ^c   Kiremit Korkut, Nese ^b   Parlak, Mesut ^b  

^a Bilge Hospital   (Turkey)

^b ISTANBUL UNIVERSITY   (Turkey)

^c ISTANBUL UNIVERSITY   (Turkey)

Author keywords

Acute radiation proctitis; Betamethasone; Formalin; Mesalazine; Misoprostol

Indexed keywords

BETAMETHASONE SODIUM PHOSPHATE; FORMALDEHYDE; MESALAZINE; MISOPROSTOL; SODIUM CHLORIDE;

ACUTE DISEASE; ANIMAL CELL; ANIMAL EUTHANASIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DISEASE MODEL; FEMALE; HISTOPATHOLOGY; INFLAMMATION; INTESTINE EPITHELIUM; LAMINA PROPRIA; NONHUMAN; PREVALENCE; PROCTITIS; RADIATION INJURY; RAT; SCORING SYSTEM;

EID: 33748309450     PISSN: 10079327     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (30)

1. Baughan CA, Canney PA, Buchanan RB, Pickering RM. A randomized trial to assess the efficacy of 5-aminosalicylic acid for the prevention of radiation enteritis. Clin Oncol (R Coll Radiol) 1993; 5: 19-24
2. Fajardo LF, Berthrong M. Radiation injury in surgical pathology. Part III. Salivary glands, pancreas and skin. Am J Surg Pathol 1981; 5: 279-296
3. Hellman S. Principles of Cancer Menagement: Radiation Therapy. In VT DeVita, S. Hellman SA. Rosenberg, (Eds): Cancer -Principles and Practice of Oncology, 5th ed. Com. Philadelphia: New York, Lippincott-Raven Press, 1997: 307-321
4. Isenberg GA, Goldstein SD, Resnik AM. Formalin therapy for radiation proctitis. JAMA 1994; 272: 1822
5. Denton AS, Andreyev HJ, Forbes A, Maher EJ. Systematic review for non-surgical interventions for the management of late radiation proctitis. Br J Cancer 2002; 87: 134-143
6. Henriksson R, Franzen L, Littbrand B. Prevention and therapy of radiation-induced bowel discomfort. Scand J Gastroenterol Suppl 1992; 191: 7-11
7. Hovdenak N, Fajardo LF, Hauer-Jensen M. Acute radiation proctitis: a sequential clinicopathologic study during pelvic radiotherapy. Int J Radiat Oncol Biol Phys 2000; 48: 1111-1117
8. Kneebone A, Mameghan H, Bolin T, Berry M, Turner S, Kearsley J, Graham P, Fisher R, Delaney G. The effect of oral sucralfate on the acute proctitis associated with prostate radiotherapy: a double-blind, randomized trial. Int J Radiat Oncol Biol Phys 2001; 51: 628-635
9. Zimmermann FB, Feldmann HJ. Radiation proctitis. Clinical and pathological manifestations, therapy and prophylaxis of acute and late injurious effects of radiation on the rectal mucosa. Strahlenther Onkol 1998; 174 Suppl 3: 85-89
10. Fischer L, Kimose HH, Spjeldnaes N, Wara P. Late progress of radiation-induced proctitis. Acta Chir Scand 1990; 156: 801-805
11. Tjandra JJ, Sengupta S. Argon plasma coagulation is an effective treatment for refractory hemorrhagic radiation proctitis. Dis Colon Rectum 2001; 44: 1759-1765; discussion 1771
12. Luna-Perez P, Rodriguez-Ramirez SE. Formalin instillation for refractory radiation-induced hemorrhagic proctitis. J Surg Oncol 2002; 80: 41-44
13. Cavcic J, Turcic J, Martinac P, Jelincic Z, Zupancic B, Panijan-Pezerovic R, Unusic J. Metronidazole in the treatment of chronic radiation proctitis: clinical trial. Croat Med J 2000; 41: 314-318
14. Cunningham IG. The management of radiation proctitis. Aust N Z J Surg 1980; 50: 172-178
15. Das KM. Sulfasalazine therapy in inflammatory bowel disease. Gastroenterol Clin North Am 1989; 18: 1-20
16. Freund U, Scholmerich J, Siems H, Kluge F, Schafer HE, Wannenmacher M. Unwanted side-effects in using mesalazine (5-aminosalicylic acid) during radiotherapy. Strahlenther Onkol 1987; 163: 678-680
17. Gilinsky NH, Burns DG, Barbezat GO, Levin W, Myers HS, Marks IN. The natural history of radiation-induced proctosigmoiditis: an analysis of 88 patients. Q J Med 1983; 52: 40-53
18. Hanson WR, DeLaurentiis K. Comparison of in vivo murine intestinal radiation protection by E-prostaglandins. Prostaglandins 1987; 33 Suppl: 93-104
19. Hong JJ, Park W, Ehrenpreis ED. Review article: current therapeutic options for radiation proctopathy. Aliment Pharmacol Ther 2001; 15: 1253-1262
20. Kan S, Chun M, Jin YM, Cho MS, Oh YT, Ahn BO, Oh TY. A rat model for radiation-induced proctitis. J Korean Med Sci 2000; 15: 682-689
21. van Bodegraven AA, Boer RO, Lourens J, Tuynman HA, Sindram JW. Distribution of mesalazine enemas in active and quiescent ulcerative colitis. Aliment Pharmacol Ther 1996; 10: 327-332
22. Gul YA, Prasannan S, Jabar FM, Shaker AR, Moissinac K. Pharmacotherapy for chronic hemorrhagic radiation proctitis. World J Surg 2002; 26: 1499-1502
23. Khan AM, Birk JW, Anderson JC, Georgsson M, Park TL, Smith CJ, Comer GM. A prospective randomized placebo-controlled double-blinded pilot study of misoprostol rectal suppositories in the prevention of acute and chronic radiation proctitis symptoms in prostate cancer patients. Am J Gastroenterol 2000; 95: 1961-1966
24. Mathai V, Seow-Choen F. Endoluminal formalin therapy for haemorrhagic radiation proctitis. Br J Surg 1995; 82: 190
25. Ouwendijk R, Tetteroo GW, Bode W, de Graaf EJ. Local formalin instillation: an effective treatment for uncontrolled radiation-induced hemorrhagic proctitis. Dig Surg 2002; 19: 52-55
26. Rubinstein E, Ibsen T, Rasmussen RB, Reimer E, Sorensen BL. Formalin treatment of radiation-induced hemorrhagic proctitis. Am J Gastroenterol 1986; 81: 44-45
27. Schultheiss TE, Lee WR, Hunt MA, Hanlon AL, Peter RS, Hanks GE. Late GI and GU complications in the treatment of prostate cancer. Int J Radiat Oncol Biol Phys 1997; 37: 3-11
28. Wang CJ, Leung SW, Chen HC, Sun LM, Fang FM, Huang EY, Hsiung CY, Changchien CC. The correlation of acute toxicity and late rectal injury in radiotherapy for cervical carcinoma: evidence suggestive of consequential late effect (CQLE). Int J Radiat Oncol Biol Phys 1998; 40: 85-91
29. Northway MG, Scobey MW, Geisinger KR. Radiation proctitis in the rat. Sequential changes and effects of anti-inflammatory agents. Cancer 1988; 62: 1962-1969
30. Stein RB, Hanauer SB. Medical therapy for inflammatory bowel disease. Gastroenterol Clin North Am 1999; 28: 297-321