Expression and properties of recombinant ovine uterine serpin

Experimental Biology and Medicine

Volumn 231, Issue 8, 2006, Pages 1313-1322

  Tekin, Şaban ^a,b   Padua, Maria B ^a   Brad, Amber M ^a   Rhodes, Michelle L ^a   Hansen, Peter J ^a  

^a UNIVERSITY OF FLORIDA   (United States)

^b GAZIOSMANPASA UNIVERSITY   (Turkey)

Author keywords

Cell proliferation; Lymphocytes; Serpin; Uterus

Indexed keywords

COMPLEMENTARY DNA; PLASMID VECTOR; RECOMBINANT OVINE UTERINE SERPIN; RECOMBINANT PROTEIN; SERINE PROTEINASE INHIBITOR; UNCLASSIFIED DRUG;

ARTICLE; BLASTOCYST; CELL PROLIFERATION; CONTROLLED STUDY; DRUG INHIBITION; ESCHERICHIA COLI; GENE AMPLIFICATION; GENE INSERTION; GENETIC TRANSFECTION; LYMPHOCYTE PROLIFERATION; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA EXTRACTION; SHEEP; UTERUS FLUID;

BOS TAURUS; ESCHERICHIA COLI; OVIS; OVIS ARIES;

EID: 33748308761     PISSN: 15353702     EISSN: 15353699     Source Type: Journal    
DOI: 10.1177/153537020623100805     Document Type: Article

References (28)

1. Ing NH, Roberts RM. The major progesterone-induced proteins secreted into the sheep uterus are members of the serpin superfamily of protease inhibitors. J Biol Chem 264:3372-3379, 1989.
2. Mathialagan N, Hansen TR. Pepsin-inhibitory activity of the uterine serpins. Proc Natl Acad Sci U S A 93:13653-13658, 1996.
3. Malathy PV, Imakawa K, Simmen RC, Roberts RM. Molecular cloning of the uteroferrin-associated protein, a major progesterone-induced serpin secreted by the porcine uterus, and the expression of its mRNA during pregnancy. Mol Endocrinol 4:428-440, 1990.
4. Tekin S, Padua MB, Newton GR, Hansen PJ. Identification and cloning of caprine uterine serpin. Mol Reprod Dev 70:262-270, 2005.
5. Peltier MR, Grant TR, Hansen PJ. Distinct physical and structural properties of the ovine uterine serpin. Biochim Biophys Acta 1479:37-51, 2000.
6. Hansen PJ, Newton GR. Binding of immunoglobulins to the major progesterone-induced proteins of the sheep uterus. Arch Biochem Biophys 260:208-217, 1988.
7. McFarlane JR, Foulds LM, O'Connor AE, Phillips DJ, Jenkin G, Hearn MT, de Kretser DM. Uterine milk protein, a novel activin-binding protein, is present in ovine allantoic fluid. Endocrinology 140:4745-4752, 1999.
8. Segerson EC, Moffatt RJ, Bazer FW, Roberts RM. Suppression of phytohemagglutinin-stimulated lymphocyte blastogenesis by ovine uterine milk protein. Biol Reprod 30:1175-1186, 1984.
9. Skopets B, Hansen PJ. Identification of the predominant proteins in uterine fluids of unilaterally pregnant ewes that inhibit lymphocyte proliferation. Biol Reprod 49:997-1007, 1993.
10. Skopets B, Liu WJ, Hansen PJ. Effects of endometrial serpin-like proteins on immune responses in sheep. Am J Reprod Immunol 33:86-93, 1995.
11. Peltier MR, Liu WJ, Hansen PJ. Regulation of lymphocyte proliferation by uterine serpin: interleukin-2 mRNA production, CD25 expression and responsiveness to interleukin-2. Proc Soc Exp Biol Med. 223:75-81, 2000.
12. Liu WJ, Hansen PJ. Effect of the progesterone-induced serpin-like proteins of the sheep endometrium on natural-killer cell activity in sheep and mice. Biol Reprod 49:1008-1014, 1993.
13. Tekin S, Hansen PJ. Natural killer-like cells in the sheep: functional characterization and regulation by pregnancy-associated proteins. Exp Biol Med 227:803-811, 2002.
14. Tekin S, Padua MB, Hansen PJ. Antiproliferative and embryoinhibitory actions of ovine uterine serpin. Am J Reprod Immunol 53:136-143, 2005.
15. Moffatt J, Bazer FW, Hansen PJ, Chun PW, Roberts RM. Purification, secretion and immunocytochemical localization of the uterine milk proteins, major progesterone-induced proteins in the uterine secretions of the sheep. Biol Reprod 36:419-430, 1987.
16. Stephenson DC, Low BG, Newton GR, Leslie MV, Hansen PJ, Bazer FW. Secretion of the major progesterone-induced proteins of the sheep uterus by caruncular and intercaruncular endometrium of the pregnant ewe from days 20-140 of gestation. Domest Anim Endocrinol 6:349-362, 1989.
17. Bazer FW, Roberts RM, Basha SM, Zavy MT, Caton D, Barron DH. Method for obtaining ovine uterine secretions from unilaterally pregnant ewes. J Anim Sci 49:1522-1527, 1979.
18. Bradford MM. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 78:248-254, 1976.
19. Padua MB, Tekin S, Spencer TE, Hansen PJ. Actions of progesterone on uterine immunosuppression and endometrial gland development in the uterine gland knockout (UGKO) ewe. Mol Reprod Dev 71:347-357, 2005.
20. Leslie MV, Hansen PJ, Newton GR. Uterine secretions of the cow contain proteins that are immunochemically related to the major progesterone-induced proteins of the sheep uterus. Domest Anim Endocrinol 7:517-526, 1990.
21. 2α, and the nitric oxide generator, sodium nitroprusside dihydrate, on oocyte maturation and embryonic development in cattle. Am J Reprod Immunol 50:263-272, 2003.
22. Sheng S, Pemberton PA, Sager R. Production, purification, and characterization of recombinant maspin proteins. J Biol Chem 269:30988-30993, 1994.
23. Jiang N, Meng Y, Zhang S, Mensah-Osman E, Sheng S. Maspin sensitizes breast carcinoma cells to induced apoptosis. Oncogene 21:4089-4098, 2002.
24. McGowen R, Biliran H Jr, Sager R, Sheng S. The surface of prostate carcinoma DU145 cells mediates the inhibition of urokinase-type plasminogen activator by maspin. Cancer Res 60:4771-4778, 2000.
25. Silverman GA, Bird PI, Carrell RW, Church FC, Coughlin PB, Gettins PG, Irving JA, Lomas DA, Luke CJ, Moyer RW, Pemberton PA, Remold-O'Donnell E, Salvesen GS, Travis J, Whisstock JC. The serpins are an expanding superfamily of structurally similar but functionally diverse proteins. Evolution, mechanism of inhibition, novel functions, and a revised nomenclature. J Biol Chem 276:33293-33296, 2001.
26. Hansen PJ. Regulation of uterine immune function by progesterone - lessons from the sheep. J Reprod Immunol 40:63-79, 1998.
27. Ing NH, Francis H, McDonnell JJ, Amann JF, Roberts RM. Progesterone induction of the uterine milk proteins: major secretory proteins of sheep endometrium. Biol Reprod 41:643-654, 1989.
28. Stewart MD, Johnson GA, Burghardt RC, Schuler LA, Joyce MM, Bazer FW, Spencer TE. Prolactin receptor and uterine milk protein expression in the ovine uterus. Biol Reprod 62:1779-1789, 2000.