Identification and cloning of caprine uterine serpin

Molecular Reproduction and Development

Volumn 70, Issue 3, 2005, Pages 262-270

  Tekin, Saban ^a,b   Padua, Maria B ^a   Newton, Gary R ^c   Hansen, Peter J ^a  

^a UNIVERSITY OF FLORIDA   (United States)

^b GAZIOSMANPASA UNIVERSITY   (Turkey)

^c PRAIRIE VIEW A AND M UNIVERSITY   (United States)

Author keywords

Caprine; Endometrium; Ovine; Pregnancy; Serpin; Uterus

Indexed keywords

ALANINE; AMINO ACID; CYSTEINE; MONOCLONAL ANTIBODY; PROTEINASE INHIBITOR; RNA; SERINE; SERINE PROTEINASE INHIBITOR; SIGNAL PEPTIDE; VALINE;

ALPHA HELIX; AMINO ACID SEQUENCE; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BOUS GENE; CATTLE; CAUS GENE; CONSENSUS SEQUENCE; CONTROLLED STUDY; COW; DNA SEQUENCE; ENDOMETRIUM; ENZYME ACTIVITY; ENZYME INHIBITION; ESTRUS CYCLE; GENE; GENE AMPLIFICATION; GENE EXPRESSION; GOAT; IMMUNOHISTOCHEMISTRY; IMMUNOLOCALIZATION; MOLECULAR CLONING; NONHUMAN; NUCLEIC ACID BASE SUBSTITUTION; NUCLEOTIDE SEQUENCE; OVUS GENE; PHYLOGENY; POUS1 GENE; POUS2 GENE; PREGNANCY; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DEGRADATION; PROTEIN LOCALIZATION; SEQUENCE ANALYSIS; SEQUENCE HOMOLOGY; SHEEP; SPECIES DIFFERENCE; SWINE; UTERINE SERPIN GENE; UTERUS; UTERUS FLUID; UTERUS HORN; WESTERN BLOTTING;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; BLOTTING, WESTERN; CLONING, MOLECULAR; DNA PRIMERS; DNA, COMPLEMENTARY; ENDOMETRIUM; FEMALE; GOATS; IMMUNOHISTOCHEMISTRY; MOLECULAR SEQUENCE DATA; PREGNANCY; SEQUENCE ALIGNMENT; SEQUENCE ANALYSIS, DNA; SERPINS; SPECIES SPECIFICITY; UTERUS;

BOS TAURUS; BOVINAE; CAPRA; CAPRA HIRCUS; OVIS; OVIS ARIES; SUIDAE; SUS SCROFA;

EID: 12844277243     PISSN: 1040452X     EISSN: None     Source Type: Journal    
DOI: 10.1002/mrd.20206     Document Type: Article

References (31)

1. Baumbach GA, Ketcham CM, Richardson DE, Bazer FW, Roberts RM. 1986. Isolation and characterization of a high molecular weight stable pink form of uteroferrin from uterine secretions and allantoic fluid of pigs. J Biol Chem 261:12869-12878.
2. Bazer FW, Roberts RM, Basha SMM, Zavy MT, Carton D, Barron DH. 1979. Method for obtaining ovine uterine secretions from unilaterally pregnant ewes. J Anim Sci 49:1522-1527.
3. Bendtsen JD, Nielsen H, von Heijne G, Brunak S. 2004. Improved prediction of signal peptides: Signal P 3.0. J Mol Biol 340:783-795.
4. Carroll RL. 1988. Vertebrate palaeontology and evolution. New York: Freeman.
5. De Rose R, Scheerlinck JP, Casey G, Wood PR, Tennent JM, Chaplin PJ. 2000. Ovine interleukin-12: Analysis of biologic function and species comparison. J Interferon Cytokine Res 20:557-564.
6. Ealy AD, Wagner SK, Sheils AE, Whitley NC, Kiesling DO, Johnson SE, Barbato GF. 2004. Identification of interferon-τ isoforms expressed by the peri-implantation goat (Capra hircus) conceptus. Dornest Anim Endocrinol 27:39-49.
7. Hansen PJ. 1998. Regulation of uterine immune function by progesterone-lessons from the sheep. J Reprod Immunol 40:63-79.
8. Hansen PJ, Liu W-J. 1994. Biochemical/physiological properties of endometrial serpin-like proteins. Adv Contracept Delivery Sys 10:339-353.
9. Hansen PJ, Ing NH, Moffatt RJ, Baumbach GA, Saunders PT, Bazer FW, Roberts RM. 1987. Biochemical characterization and biosynthesis of the uterine milk proteins of the pregnant sheep uterus. Biol Reprod 36:405-418.
10. Higgins D, Thompson J, Gibson T, Thompson JD, Higgins DG, Gibson TJ. 1994. CLUSTAL W: Improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties, and weight matrix choice. Nucleic Acids Res 22:4673-4680.
11. Hopkins PC, Carrell RW, Stone SR. 1993. Effects of mutations in the hinge region of serpins. Biochemistry 32:7650-7657.
12. Horikawa R, Gaylinn BD, Lyons CE, Jr., Thorner MO. 2001. Molecular cloning of ovine and bovine growth hormone-releasing hormone receptors: The ovine receptor is C-terminally truncated. Endocrinology 142:2660-2668.
13. Ing NH, Roberts RM. 1989. The major progesterone-induced proteins secreted into the sheep uterus are members of the serpin superfamily of protease inhibitors. J Biol Chem 264:3372-3379.
14. Ing NH, Francis H, McDonnell JJ, Amann JF, Roberts RM. 1989. Progesterone induction of the uterine milk proteins: Major secretory proteins of sheep endometrium. Biol Reprod 41:643-654.
15. Irving JA, Pike RN, Lesk AM, Whisstock JC. 2000. Phylogeny of the serpin superfamily: Implications of patterns of amino acid conservation for structure and function. Genome Res 10:1845-1864.
16. Leslie MV, Hansen PJ. 1991. Progesterone-regulated secretion of the serpin-like proteins of the ovine and bovine uterus. Steroids 56:589-597.
17. Leslie MV, Hansen PJ, Newton GR. 1990. Uterine secretions of the cow contain proteins that are immunochemically related to the major progesterone-induced proteins of the sheep uterus. Dornest Anim Endocrinol 7:517-526.
18. Malathy PV, Imakawa K, Simmen RC, Roberts RM. 1990. Molecular cloning of the uteroferrin-associated protein: A major progesterone-induced serpin secreted by the porcine uterus, and the expression of its mRNA during pregnancy. Mol Endocrinol 4:428-440.
19. Mansour MM, Machen MR, Tarleton BJ, Wiley AA, Wower J, Bartol FF, Goyal HO. 2001. Expression and molecular characterization of estrogen receptor alpha messenger RNA in male reproductive organs of adult goats. Biol Reprod 64:1432-1438.
20. Mathialagan N, Hansen TR. 1996. Pepsin-inhibitory activity of the uterine serpins. Proc Natl Acad Sci USA 93:13653-13658.
21. Moffatt J, Bazer FW, Hansen PJ, Chun PW, Roberts RM. 1987. Purification, secretion, and immunocytochemical localization of the uterine milk proteins, major progesterone-induced proteins in the uterine secretions of the sheep. Biol Reprod 36:419-430.
22. Murray MK, Malathy PV, Bazer FW, Roberts RM. 1989. Structural relationship, biosynthesis, and immunocytochemical localization of uteroferrin-associated basic glycoproteins. J Biol Chem 264:4143-4150.
23. Peltier MR, Liu WJ, Hansen PJ. 2000a. Regulation of lymphocyte proliferation by uterine serpin: Interleukin-2 mRNA production, CD25 expression, and responsiveness to interleukin-2. Proc Soc Exp Biol Med 223:75-81.
24. Peltier MR, Raley LC, Liberles DA, Benner SA, Hansen PJ. 2000b. Evolutionary history of the uterine serpins. J Exp Zool 288:165-174.
25. Peltier MR, Grant TR, Hansen PJ. 2000c. Distinct physical and structural properties of the ovine uterine serpin. Biochim Biophys Acta 1479:37-51.
26. Segerson EC, Moffatt RJ, Bazer FW, Roberts RM. 1984. Suppression of phytohemagglutinin-stimulated lymphocyte blastogenesis by ovine uterine milk protein. Biol Reprod 30:1175-1186.
27. Silverman GA, Bird PI, Carrell RW, Church FC, Coughlin PB, Gettins PG, Irving JA, Lomas DA, Luke CJ, Moyer RW, Pemberton PA, Remold-O'Donnell E, Salvesen GS, Travis J, Whisstock JC. 2001. The serpins are an expanding superfamily of structurally similar but functionally diverse proteins. Evolution, mechanism of inhibition, novel functions, and a revised nomenclature. J Biol Chem 276: 33293-33296.
28. Skopets B, Hansen PJ. 1993. Identification of the predominant proteins in uterine fluids of unilaterally pregnant ewes that inhibit lymphocyte proliferation. Biol Reprod 49:997-1007.
29. Skopets B, Liu WJ, Hansen PJ. 1995. Effects of endometrial serpin-like proteins on immune responses in sheep. Am J Reprod Immunol 33:86-93.
30. Stephenson DC, Leslie MV, Low BG, Newton GR, Hansen PJ, Bazer FW. 1989. Secretion of the major progesterone-induced proteins of the sheep uterus by caruncular and intercaruncular endometrium of the pregnant ewe from days 20 to 140 of gestation. Dornest Anim Endocrinol 6:349-362.
31. von Heijne G. 1985. Signal sequences. The limits of variation. J Mol Biol 84:99-105.