Comparison of interferon monotherapy with interferon-lamivudine combination treatment in children with chronic hepatitis B

Indian Journal of Gastroenterology

Volumn 25, Issue 3, 2006, Pages 136-139

  Sokucu, Semra ^a   Gokce, Selim ^a,b   Suoglu, Ozlem Durmaz ^a   Emiroglu, Haldun ^a   Cevikbas, Ugur ^a  

^a ISTANBUL UNIVERSITY   (Turkey)

^b NONE   (Turkey)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE AMINOTRANSFERASE; HEPATITIS B(E) ANTIGEN; LAMIVUDINE; RECOMBINANT ALPHA2B INTERFERON;

ARTICLE; CHILD; CHRONIC HEPATITIS; CONTROLLED STUDY; DOSE RESPONSE; DRUG RESPONSE; FOLLOW UP; HEPATITIS B; HUMAN; MAJOR CLINICAL STUDY; MONOTHERAPY; RETROSPECTIVE STUDY; SEROCONVERSION;

ADOLESCENT; ALANINE TRANSAMINASE; ANTIVIRAL AGENTS; CHILD; CHILD, PRESCHOOL; DNA, VIRAL; DRUG RESISTANCE, VIRAL; DRUG THERAPY, COMBINATION; FEMALE; FOLLOW-UP STUDIES; HEPATITIS B E ANTIGENS; HEPATITIS B VIRUS; HEPATITIS B, CHRONIC; HUMANS; INTERFERONS; LAMIVUDINE; MALE; RETROSPECTIVE STUDIES; TREATMENT OUTCOME;

EID: 33748302816     PISSN: 02548860     EISSN: 02548860     Source Type: Journal    
DOI: None     Document Type: Article

References (24)

1. Sokal E. Drug treatment of pediatric chronic hepatitis B. Pediatr Drugs 2002;4:361-9.
2. Dikici B, Ozgenc F, Kalayci AG, Targan S, Ozkan T, Selimoglu A, et al . Current therapeutic approaches in childhood chronic hepatitis B infection: a multicenter study. J Gastroenterol Hepatol 2004;19:127-33.
3. Wong WWS, Tyrrell DLJ. Treatment of hepatitis B virus with lamuvidine. In: Schinazi RF, Sommadossi JP, Thomas HC, Eds. Therapies for Viral Hepatitis. London: International Medical Press. 1998: p. 353-63.
4. Leung NWY, Lai C-L, Chang T-T, Guan R, Lee CM, Ng KY, et al . Asia Hepatitis Lamivudine Study Group. Extended lamivudine treatment in patients with chronic hepatitis B enhances hepatitis B e antigen seroconversion rates: results after 3 years of therapy. Hepatology 2001;33:1527-32.
5. Ozgenc F, Arikan C, Sertoz RY, Nart D, Aydogdu S, Yagci RV. Effect of long-term lamuvidine in chronic hepatitis B virus-infected children. Antivir Ther 2004;9:729-32.
6. Mutimer D, Dowling D, Cane P, Ratcliffe D, Tang H, O'Donnell K, et al . Additive antiviral effects of lamivudine and alpha-interferon in chronic hepatitis B infection. Antivir Ther 2000;5:273-7.
7. Barbaro G, Zechini F, Pellicelli AM, Francavilla R, Scotto G, Bacca D, et al . Long-term efficacy of interferon alpha-2b and lamivudine in combination compared to lamivudine monotherapy in patients with chronic hepatitis B. An Italian multicenter, randomized trial. J Hepatol 2001;35:406-11.
8. Dikici B, Bosnak M, Bosnak V, Dagli A, Davutoglu M, Yagci RV, et al . Comparison of treatments of chronic hepatitis B in children with lamivudine and alpha-interferon combination and alpha-interferon alone. Pediatr Int 2002; 44:517-21.
9. Lai CL, Ratziu V, Yuen MF, Poynard T. Viral hepatitis B. Lancet 2003;362:2089-94.
10. Desmet VJ, Germer M, Hoofnagle JH, Manns M, Scheuer PJ. Classification of chronic hepatitis: diagnosis, grading and staging. Hepatology 1994;19:1513-20.
11. Sokal EM, Conjeevaram HS, Roberts EA, Alvarez F, Bern EM, Goyens P, et al . Interferon alpha therapy for chronic hepatitis B in children: a multinational randomized controlled trial. Gastroenterology 1998;114:988-95.
12. Lau DT, Khokhar MF, Doo F, Ghany MG, Herion D, Park Y, et al . Long-term therapy of hepatitis B with lamivudine. Hepatology 2000;32:828-34.
13. Yeh C-T, Chien R-L, Chu C-M, Liaw Y-F. Clearance of the original hepatitis B virus YMDD-motif mutants with emergence of distinct lamivudine-resistance mutants during prolonged lamivudine therapy. Hepatology 2000;31:1318-26.
14. Schalm SW. Lamivudine-interferon combination therapy for chronic hepatitis B: further support but no conclusive evidence. J Hepatol 2001;35:419-20.
15. Dikici B, Bosnak M, Kara H, Dogru O, Dagli A, Gurkan F, et al . Lamivudine and interferon-alpha combination treatment of childhood patients with chronic hepatitis B infection. Pediatr Infect Dis J 2001;20:988-92.
16. Demirturk N, Usluer G, Ozgunes I, Çolak H, Kartal ED, Dincer S. Comparison of different treatment combinations for chronic hepatitis B infection. J Chemother 2002;14:285-9.
17. Selimoglu MA, Aydogdu S, Unal F, Zeytinoglu A, Yuce G, Yagci RV. Alpha interferon and lamivudine combination therapy for chronic hepatitis B in children. Pediatr Int 2002;44:404-8.
18. Lai CL, Chien RN, Leung NWY. A one-year trial of lamivudine for chronic hepatitis B . N Engl J Med 1998;339:61-8.
19. Dienstag JL, Schiff ER,Wright TL. Lamivudine as initial treatment for chronic hepatitis B in United States. N Engl J Med 1999;341:1256-63.
20. Torre D, Tambini R. Interferon-alpha therapy for chronic hepatitis B in children: a meta-analysis. Clin Infect Dis 1996;23:131-7.
21. Ruiz-Moreno M, Camps T, Jimenez J, Lopez R, Castillo I, Bartolome J, et al . Factors predictive of response to interferon therapy in children with chronic hepatitis B. J Hepatol 1995;22:540-4.
22. Liaw YF, Leung NW, Chang TT, Guan R, Tai DI, Ng KY, et al . Effects of extended lamivudine therapy in Asian patients with chronic hepatitis B. Asia Hepatitis Lamivudine Study Group. Gastroenterology 2000;119:172-80.
23. Lai CL, Chien RN, Leung NW, Chang TT, Guan R, Tai DI, et al . A one-year trial of lamivudine for chronic hepatitis B. Asia Hepatitis Lamivudine Study Group. N Engl J Med 1998;339:61-8.
24. Liaw YF. Results of lamivudine trials in Asia. J Hepatol 2003;39:111-5.