Cytokeratin expression patterns of gastric carcinomas according to Lauren and Goseki classification

Applied Immunohistochemistry and Molecular Morphology

Volumn 14, Issue 3, 2006, Pages 303-308

  Gürbüz, Yeşim ^a,b   Köse, Nur ^a  

^a KOCAELI UNIVERSITY   (Turkey)

^b G6A/8 PC 41050 Yahyakaptan   (Turkey)

Author keywords

CK19; CK20; CK7; CK8; Gastric carcinoma; Goseki classification; Immunohistochemistry; Lauren classification

Indexed keywords

CYTOKERATIN 19; CYTOKERATIN 20; CYTOKERATIN 7; CYTOKERATIN 8;

ADULT; AGED; ARTICLE; CANCER CLASSIFICATION; CANCER GRADING; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN TISSUE; IMMUNOPHENOTYPING; IMMUNOREACTIVITY; INTESTINE TUMOR; MALE; PRIORITY JOURNAL; PROTEIN EXPRESSION; STATISTICAL ANALYSIS; STOMACH CARCINOMA; STOMACH MUCOSA;

EID: 33748279107     PISSN: 15412016     EISSN: 15334058     Source Type: Journal    
DOI: 10.1097/00129039-200609000-00008     Document Type: Article

References (31)

1. Owen DA. Alimentary canal and associated organs: the stomach. In: Carter D, Greenson JK, Oberman HA, et al, eds. Sternberg's Diagnostic Surgical Pathology. Philadelphia: Lippincott Williams & Wilkins; 2004:1435-1475.
2. Feneglio-Phreiser C, Carnerio F, Correa P, et al. Gastric carcinoma. In: Hamilton SR, Aaltonen LA, eds. WHO classification of tumours, Pathology and genetics. Tumours of the Digestive System, tumours of the stomach. Lyon: IARC Press; 2000:39-52.
3. Lauren P. The two histological main types of gastric carcinoma: diffuse and so-called intestinal type carcinoma. Acta Pathol Microbiol Scand. 1965;64:31-49.
4. Goseki N, Takizawa T, Koike M. Differences in the mode of the extension of gastric cancer classified by histological type: new histological classification of gastric carcinoma. Gut. 1992;33:606-612.
5. Songun I, Von de Velde CJH, Arends JW, et al. Classification of gastric carcinoma using the Goseki system provides prognostic information additional to TNM staging. Cancer. 1999;85:2114-2118.
6. Martin IG, Dixon MF, Sue-ling H, et al. Goseki histological grading of gastric cancer is an important predictor of outcome. Gut. 1994;35:758-763.
7. Gurbuz Y, Khalke V, Kloppel G. How do gastric carcinoma classification systems relate to mucin expression patterns? An immunohistochemical analysis in a series of advanced gastric carcinomas. Virchows Arch. 2002;440:505-511.
8. Hattori T, Kushima R. Gastric differentiated stomach adenocarcinoma. Pathologe. 2001;22:97-104.
9. Osborn M, Mazzoleni G, Santini D, et al. Intestinal brush border hydrolases and keratin polypeptides in intestinal metaplasia and gastric cancer: an immunohistologic study emphasizing the different degrees of intestinal and gastric differentiation in signet ring cell carcinomas. Virchows Arch A Pathol Anat. 1998;413:303-312.
10. Chu P, Wu E, Weiss LM. Cytokeratin 7 and cytokeratin 20 expression in epithelial neoplasms: a survey of 435 cases. Mod Pathol. 2000;13:962-972.
11. Moll R. Cytokeratins in the histological diagnosis of malignant tumor. Int J Biomarkers. 1994;9:63-69.
12. Moll R, Lowe A, Laufer J, et al. Cytokeratin 20 in human carcinomas: a new histodiagnostic marker defected by monoclonal antibodies. Am J Pathol. 1992;140:427-447.
13. Schwerer MJ, Baczako K. Expression of cytokeratins typical for ductal and squamous, differentiation in the human stomach: an immunohistochemical study of normal foveolar epithelium, Helicobacter pylori gastritis and intestinal metaplasia. Histopathology. 1996;29:131-137.
14. Wauters CCAP, Smedts F, Gerrits LGM, et al. Keratins 7 and 20 as diagnostic markers of carcinomas metastatic to the ovary. Hum Pathol. 1995;26:852-855.
15. McLaren KM, Burnett RA, Goodlad JR, et al. Scottish Pathology Consistency Group. Observer variability in the Goseki grouping of gastric adenocarcinoma in resection and biopsy specimens. Histopathology. 2003;42:472-475.
16. Monig S, Baldus SE, Collet PH, et al. Histological grading in gastric cancer by Goseki classification correlation with histopathological subtypes and prognosis. Anticancer Res. 2001;21:617-620.
17. Fontana MG, La Pinta M, Moneghini D, et al. Prognostic value of Goseki histological classification in adenocarcinoma of the cardia. Br J Cancer. 2003;88:401-405.
18. Ventura L, Chiominto A, Discepoli S, et al. Lack of prognostic significance in Goseki grading of gastric carcinoma. J Exp Clin Cancer Res. 2002;21:225-227.
19. Owen DA. Alimentary canal, stomach. In: Sternberg SS, ed. Histology for Pathologists. Philadelphia: Lippincott Williams & Wilkins; 1997:481-495.
20. Schwerer MJ, Kraft K, Baczako K. Structural changes in the gastric foveolar epithelium in Helicobacter pylori-positive gastritis revealed by keratin immunohistochemistry. Hum Pathol. 1996;28:1260-1267.
21. Ronnett BM, Kurman RJ, Shmookler BO, et al. The morphologic spectrum of ovarian metastases of appendiceal adenocarcinomas; a clinicopathologic and immunohistochemical analysis of tumors often misinterpreted as primary ovarian tumor or metastatic tumors from other gastrointestinal sites. Am J Surg Pathol. 1997;21:1145-1155.
22. Park YS, Kim HS, Hong EK, et al. Expression of cytokeratins 7 and 20 in primary carcinomas of the stomach and colorectum and their value in the differential diagnosis of metastatic carcinomas to the ovary. Hum Pathol. 2002;33:1078-1085.
23. Kirchner T, Muller S, Hattori T, et al. Metaplasia, intraepithelial neoplasia and early cancer of the stomach are related to dedifferentiated epithelial cells defined by cytokeratin 7 expression in gastritis. Virchows Arch. 2001;439:512-522.
24. Tang P, Soukkary S, Kahn E. Mature cystic teratoma of the ovary associated with complete colonic wall and mucinous cystadenoma. Ann Clin Lab Sci. 2003;33:465-470.
25. Ormsby AH, Goldblum JR, Rice TW, et al. The utility of cytokeratin subsets in distinguishing, Barrett's-related oesophageal adenocarcinoma from gastric adenocarcinoma. Histopathology. 2001;38:307-311.
26. Goldstein NS, Long A, Kuan SF, et al. Colon signet ring cell adenocarcinoma: immunohistochemical characterization and comparison with gastric and typical colon adenocarcinomas. Appl Immunohistochem Mol Morphol. 2000;8:183-188.
27. Shen B, Ormsby AH, Shen C, et al. Cytokeratin expression patterns in noncardia, intestinal metaplasia associated gastric adenocarcinoma. Cancer. 2002;94:820-831.
28. Kim MA, Lee HS, Yang HK, et al. Cytokeratin expression profile in gastric carcinomas. Hum Pathol. 2004;35:576-581.
29. Lee MJ, Lee HS, Kim WH, et al. Expression of mucins and cytokeratins in primary carcinomas of the digestive system. Mod Pathol. 2003;16:403-410.
30. Hanski C, Hofmeier M, Schmitt Graff A, et al. Overexpression or ectopic expression of MUC2 is the common property of mucinous carcinomas of the colon, pancreas, breast and ovary. J Pathol. 1997;182:385-391.
31. Yasuda K, Shiraishi N, Inomata M, et al. Clinicopathologic characteristics of early-stage mucinous gastric carcinoma. J Clin Gastroenterol. 2004;38:507-511.