Effect of topical melatonin on ultraviolet radiation-induced suppression of Mantoux reactions in humans

Photodermatology Photoimmunology and Photomedicine

Volumn 22, Issue 5, 2006, Pages 267-269

  Howes, Renae A ^a   Halliday, Gary M ^a   Damian, Diona L ^a  

^a ROYAL PRINCE ALFRED HOSPITAL   (Australia)

Author keywords

Immunosuppression; Mantoux; Melatonin; Ultraviolet radiation

Indexed keywords

MELATONIN;

ADULT; ARTICLE; CELL VIABILITY; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CULTURE MEDIUM; DELAYED HYPERSENSITIVITY; DOSE RESPONSE; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; ERYTHEMA; FEMALE; HUMAN; HUMAN CELL; IMMUNOMODULATION; MALE; PRIORITY JOURNAL; RADIATION DOSE; RADIATION EXPOSURE; STATISTICAL SIGNIFICANCE; SUNBURN; TUBERCULIN TEST; ULTRAVIOLET RADIATION; VOLUNTEER;

ADJUVANTS, IMMUNOLOGIC; ADMINISTRATION, CUTANEOUS; ADULT; DOSE-RESPONSE RELATIONSHIP, DRUG; DOSE-RESPONSE RELATIONSHIP, RADIATION; ERYTHEMA; FEMALE; HUMANS; MALE; MELATONIN; MIDDLE AGED; SKIN; ULTRAVIOLET RAYS;

EID: 33748268495     PISSN: 09054383     EISSN: 16000781     Source Type: Journal    
DOI: 10.1111/j.1600-0781.2006.00235.x     Document Type: Article

References (6)

1. Vijayalaxmi, Thomas CR, Reiter RJ, Herman TS. Melatonin: From basic research to cancer treatment clinics. J Clin Oncol 2002; 20: 2575-2601.
2. Slominski A, Wortsman J, Tobin DJ. The cutaneous serotinergic/ melatonergic system: Securing a place under the sun. FASEB J 2002; 19: 176-194.
3. Bangha E, Elsner P, Kistler GS. Suppression of UV-induced erythema by topical treatment with melatonin (N-acetyl-5-methoxytryptamine). A dose response study. Arch Dermatol Res 1996; 288: 522-526.
4. Dreher F, Gabard B, Schwindt DA, Maibach HI. Topical melatonin in combination with vitamins E and C protects skin from ultraviolet-induced erythema: A human study in vivo. Br J Dermatol 1998; 139: 332-339.
5. Damian DL, Halliday GM. Measurement of ultraviolet radiation-induced suppression of recall contact and delayed-type hypersensitivity in humans. Methods 2002; 28: 34-45.
6. Lee KS, Lee WS, Suh S, et al. Melatonin reduces ultraviolet-B induced cell damages and polyamine levels in human skin fibroblasts in culture. Exp Mol Med 2003; 4: 263-268.