Dynamics of recurrent viral infection

Proceedings of the Royal Society B: Biological Sciences

Volumn 273, Issue 1598, 2006, Pages 2193-2199

  Yao, W ^a   Hertel, L ^a   Wahl, L M ^a  

^a UNIVERSITY OF WESTERN ONTARIO   (Canada)

Author keywords

Antibody; CTL; Mathematical model; Memory T cell; Recurrency; Viral reactivation

Indexed keywords

ANTIBODY;

ANTIBODY; INFECTIOUS DISEASE; REACTIVATION; VIRAL DISEASE;

ANTIBODY RESPONSE; ARTICLE; CYTOTOXIC T LYMPHOCYTE; DYNAMICS; MATHEMATICAL MODEL; MEMORY T LYMPHOCYTE; NONHUMAN; PRIORITY JOURNAL; RECURRENT INFECTION; VIRUS INFECTION;

EID: 33748253244     PISSN: 09628452     EISSN: 14712970     Source Type: Journal    
DOI: 10.1098/rspb.2006.3563     Document Type: Article

References (28)

1. Alcami, A. & Koszinowski, U. H. 2000 Viral mechanisms of immune evasion. Immunol. Today 21, 447-455. (doi:10. 1016/S0167-5699 (00)01699-6)
2. Antia, R., Pilyugin, S. S. & Ahmed, R. 1998 Models of immune memory: on the role of cross-reactive stimulation, competition, and homeostasis in maintaining immune memory. Proc. Natl Acad. Sci. USA 95, 14926-14931. (doi:10.1073/pnas.95.25.14926)
3. Bachmann, M. F., Hunziker, L., Zinkernagel, R. M., Storni, T. & Kopf, M. 2004 Maintenance of memory CTL responses by T helper cells and CD40-CD40 ligand: antibodies provide the key. Eur. J. Immunol. 34, 317-326. (doi: 10.1002/eji.200324717)
4. Ballow, M. 2002 Primary immunodeficiency disorders: antibody deficiency. J. Allergy Clin. Immunol. 109, 581-591. (doi: 10.1067/mai.2002.122466)
5. Bocharov, G. A. & Romanyukha, A. A. 1991 Mathematical modeling of the immune response during acute viral infections. In Theoretical and experimental insights into immunology (ed. A. S. Perelson & G. Weisbuch), pp. 309-322. Berlin: Springer.
6. Borrow, P., Tishon, A., Lee, S., Xu, J., Grewal, I. S., Oldstone, M. B. & Flavell, R. A. 1996 CD40L-deficient mice show deficits in antiviral immunity and have an impaired memory CD8+ CTL response. J. Exp. Med. 183, 2129-2142. (doi:10.1084/jem.183.5.2129)
7. De Boer, R. J., Oprea, M., Antia, R., Murali-Krishna, K., Ahmed, R. & Perelson, A. S. 2001 Recruitment times, proliferation, and apoptosis rate during the CD8 + T-cell response to lymphocytic choriomeningitis virus. J. Virol. 75, 10663-10669. (doi:10.1128/JVI.75.22.10663-10669. 2001)
8. Gerlach, J. T. et al. 1999 Recurrence of hepatitis C virus after loss of virus-specific CD4(+) T-cell response in acute hepatitis C. Gastroenterology 117, 933-941. (doi:10.1016/80016-5085(99)70353-7)
9. Ghazal, P., Garcia-Ramirez, J., Gonzalez-Armas, J., Kurz, S. & Angulo, A. 2000 Principles of homeostasis in governing virus activation and latency. Immunol. Res. 21, 219-223. (doi:10.1385/IR:21:2-3:219)
10. Gillespie, G. M. et al. 2000 Functional heterogeneity and high frequencies of cytomegalovirus-specific CD8(+) T lymphocytes in healthy seropositive donors. J. Virol. 74, 8140-8150. (doi:10.1128/JVI.74.17.8140-8150. 2000)
11. Komarova, N., Barnes, E., Klenerman, P. & Wodarz, D. 2003 Boosting immunity by antiviral drug therapy: a simple relationship among timing, efficacy, and success. Proc. Natl Acad. Sci. USA 100, 1855-1860. (doi:10.1073/pnas. 0337483100)
12. Luo, X. R., Yan, A. W., Liang, R. & Lau, G. K. K. 2001 Hepatitis B virus (HBV) reactivation after cytotoxic or immunosuppressive therapy-pathogenesis and management. Rev. Med. Virol. 11,287-299. (doi:10.1002/rmv.322)
13. Luzyanina, T, Engelborghs, K., Ehl, S., Klenerman, P. & Bocharov, G. 2001 Low level viral persistence after infection with LCMV: a quantitative insight through numerical bifurcation analysis. Math. Biosci. 173, 1-23. (doi: 10.1016/80025-5564(01)00072-4)
14. Nowak, M. A. & May, R. M. 2000 Virus dynamics: mathematical principles of immunology and virology. New York, NY: Oxford University Press.
15. Phillips, R. E. et al. 1991 Human immunodeficiency virus genetic variation that can escape cytotoxic T cell recognition. Nature 354, 453-459. (doi:10.1038/354453a)
16. Planz, O., Ehl, S., Furrer, E., Horvath, E., Bründler, M.-A., Hengartner, H. & Zinkernagel, R. M. 1997 A critical role for neutralizing-antibody-producing B cells, CD4(+) T cells, and interferons in persistent and acute infections of mice with lymphocytic choriomeningitis virus: implications for adoptive immunotherapy of virus carriers. Proc. Natl Acad. Sci. USA 94, 6874-6879. (doi:10.1073/pnas.94.13.6874)
17. Redpath, S., Angulo, A., Gascoigne, N. R. & Ghazal, P. 2001 Immune checkpoints in viral latency. Annu. Rev. Microbiol. 55, 531-560. (doi:10.1146/annurev.micro.55.1.531)
18. Roberts, R. L. & Stiehm, E. R. 2001 Antibody (B-cell) immunodeficiency disorders. In Medical immunology (ed. T. G. Parslow, D. P. Stites, A. I. Terr & J. B. Imboden) 10th edn, pp. 299-312. New York, NY: McGraw-Hill.
19. Seiden, P. E. & Celada, F. 1991 A simulation of the humoral immune system. In Theoretical and experimental insights into immunology (ed. A. S. Perelson & G. Weisbuch), pp. 49-62. Berlin: Springer.
20. Thomsen, A. R., Johansen, J., Marker, O. & Christensen, J. P. 1996 Exhaustion of CTL memory and recrudescence of viremia in lymphocytic choriomeningitis virus-infected MHC class II-deficient mice and B cell-deficient mice. J. Immunol 157, 3070-3080.
21. Thomsen, A. R., Nansen, A., Christensen, J. P., Andreasen, S. O. & Marker, O. 1998 CD40 ligand is pivotal to efficient control of virus replication in mice infected with lymphocytic choriomeningitis virus. J. Immunol. 161, 4583-4590.
22. Timm, J. et al. 2004 CD8 epitope escape and reversion in acute HCV infection. J. Exp. Med. 200, 1593-1604. (doi: 10.1084/jem.20041006)
23. Villarreal, L. P., Defilippis, V. R. & Gottleib, K. A. 2000 Acute and persistent viral life strategies and their relationship to emerging diseases. Virology 272, 1-6. (doi:10.1006/viro.2000.0381)
24. Wahl, L. M. & Nowak, M. A. 2000 Adherence and drug resistance: predictions for therapy outcome. Proc. R. Soc. B 267, 835-843. (doi:10.1098/rspb.2000.1079)
25. Wodarz, D. 2003 Hepatitis C virus dynamics and pathology: the role of CTL and antibody responses. J. Gen. Virol. 84, 1743-1750. (doi:10.1099/vir.0.19118- 0)
26. Wodarz, D. & Lloyd, A. L. 2004 Immune responses and the emergence of drug-resistant virus strains in vivo. Proc. R. Soc. B 271, 1101-1109. (doi:10.1098/rspb.2003.2664)
27. Wodarz, D. & Nowak, M. A. 2000 Correlates of cytotoxic T-lymphocyte-mediated virus control: implications for imuno-suppressive infections and their treatment. Phil. Trans. R. Soc. B 355, 1059-1070. (doi:10.1098/rstb.2000. 0643)
28. Wodarz, D., Page, K. M., Arnaout, R. A., Thomsen, A. R., Lifson, J. D. & Nowak, M. A. 2000 A new theory of cytotoxic T-lymphocyte memory: implications for HIV treatment. Phil. Trans. R. Soc. B 355, 329-343. (doi: 10. 1098/rstb.2000.0570)