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Volumn 3, Issue 3, 2006, Pages 317-327

Insulin-sensitizing and anti-proliferative effects of Argania spinosa seed extracts

Author keywords

Cancer; Diabetes; MAPK; PKB; Transformed cell lines

Indexed keywords

ARGANIA SPINOSA EXTRACT; INSULIN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PLANT EXTRACT; PROTEIN KINASE B; SAPONIN; UNCLASSIFIED DRUG; VEGETABLE OIL;

EID: 33748210066     PISSN: 1741427X     EISSN: 17414288     Source Type: Journal    
DOI: 10.1093/ecam/nel015     Document Type: Article
Times cited : (69)

References (52)
  • 1
    • 15444369658 scopus 로고    scopus 로고
    • Chemistry of the secondary metabolites of Argania spinosa (L.) skeels
    • Charrouf Z, Guillaume D. Chemistry of the secondary metabolites of Argania spinosa (L.) skeels. Curr Topics Phytochem 2002a;5:99-102.
    • (2002) Curr Topics Phytochem , vol.5 , pp. 99-102
    • Charrouf, Z.1    Guillaume, D.2
  • 2
    • 0032808913 scopus 로고    scopus 로고
    • Ethnoeconomical, ethnomedical, and phytochemical study of Argania spinosa (L.) Skeels
    • Charrouf Z, Guillaume D. Ethnoeconomical, ethnomedical, and phytochemical study of Argania spinosa (L.) Skeels. J Ethnopharmacol 1999;67:7-14.
    • (1999) J Ethnopharmacol , vol.67 , pp. 7-14
    • Charrouf, Z.1    Guillaume, D.2
  • 3
    • 0034185532 scopus 로고    scopus 로고
    • Experimental evidence of an antihypertensive and hypocholesterolemic effect of oil of argan, Argania sideroxylon
    • Berrada Y, Settaf A, Baddouri K, Cherrah A, Hassar M. Experimental evidence of an antihypertensive and hypocholesterolemic effect of oil of argan, Argania sideroxylon. Therapie 2000;55:375-8.
    • (2000) Therapie , vol.55 , pp. 375-378
    • Berrada, Y.1    Settaf, A.2    Baddouri, K.3    Cherrah, A.4    Hassar, M.5
  • 5
    • 4544249664 scopus 로고    scopus 로고
    • Evidence of hypolipemiant and antioxidant properties of argan oil derived from the argan tree (Argania spinosa)
    • Drissi A, Girona J, Cherki M, Godas G, Derouiche A, El Messal M, et al. Evidence of hypolipemiant and antioxidant properties of argan oil derived from the argan tree (Argania spinosa). Clin Nutr 2004;23:1159-66.
    • (2004) Clin Nutr , vol.23 , pp. 1159-1166
    • Drissi, A.1    Girona, J.2    Cherki, M.3    Godas, G.4    Derouiche, A.5    El Messal, M.6
  • 7
    • 0007037585 scopus 로고
    • Autoxydation dec l'huile d'argan (Argania spinosa) sapotacée du Maroc
    • Chimi H, Cillard J, Cillard P. Autoxydation dec l'huile d'argan (Argania spinosa) sapotacée du Maroc. Sciences des Aliments 1994;14:117-24.
    • (1994) Sciences des Aliments , vol.14 , pp. 117-124
    • Chimi, H.1    Cillard, J.2    Cillard, P.3
  • 8
    • 0037326784 scopus 로고    scopus 로고
    • Consumption of argan oil (Morocco) with its unique profile of fatty acids, tocopherols, squalene, sterols and phenolic compounds should confer valuable cancer chemopreventive effects
    • Khallouki F, Younos C, Soulimani R, Oster T, Charrouf Z, Spiegelhalder B, et al. Consumption of argan oil (Morocco) with its unique profile of fatty acids, tocopherols, squalene, sterols and phenolic compounds should confer valuable cancer chemopreventive effects. Eur J Cancer Prev 2003;12:67-75.
    • (2003) Eur J Cancer Prev , vol.12 , pp. 67-75
    • Khallouki, F.1    Younos, C.2    Soulimani, R.3    Oster, T.4    Charrouf, Z.5    Spiegelhalder, B.6
  • 9
    • 0001643032 scopus 로고
    • Etude de l'huile des graines d'Argania spinosa (L.) Sapotacea. II- Stérols, alcools triterpéniques et méthystérols de l'huile d'argan
    • Farines M, Charrouf M, Soulier J, Cave A. Etude de l'huile des graines d'Argania spinosa (L.) Sapotacea. II- Stérols, alcools triterpéniques et méthystérols de l'huile d'argan. Rev Franç Corps Gras 1984;31:443-8.
    • (1984) Rev Franç Corps Gras , vol.31 , pp. 443-448
    • Farines, M.1    Charrouf, M.2    Soulier, J.3    Cave, A.4
  • 10
    • 2342466734 scopus 로고    scopus 로고
    • Global prevalence of diabetes: Estimates for the year 2000 and projections for 2030
    • Wild S, Roglic G, Green A, Sicree R, King H. Global prevalence of diabetes: estimates for the year 2000 and projections for 2030. Diabetes Care 2004;27:1047-53.
    • (2004) Diabetes Care , vol.27 , pp. 1047-1053
    • Wild, S.1    Roglic, G.2    Green, A.3    Sicree, R.4    King, H.5
  • 11
    • 0141539628 scopus 로고    scopus 로고
    • Insulin signaling: Mechanisms altered in insulin resistance
    • Capeau J. Insulin signaling: mechanisms altered in insulin resistance. Med Sci (Paris) 2003;19:834-9.
    • (2003) Med Sci (Paris) , vol.19 , pp. 834-839
    • Capeau, J.1
  • 14
    • 0038410189 scopus 로고    scopus 로고
    • Synergistic activation of mitogen-activated protein kinase by insulin and adenosine triphosphate in liver cells: Permissive role of Ca2+
    • Haddad PS, Vallerand D, Mathe L, Benzeroual K, Van de Werve G. Synergistic activation of mitogen-activated protein kinase by insulin and adenosine triphosphate in liver cells: permissive role of Ca2+. Metabolism 2003;52:590-8.
    • (2003) Metabolism , vol.52 , pp. 590-598
    • Haddad, P.S.1    Vallerand, D.2    Mathe, L.3    Benzeroual, K.4    Van De Werve, G.5
  • 15
    • 0027170098 scopus 로고
    • Vasopressin increases cytosolic sodium concentration in hepatocytes and activates calcium influx through cation-selective channels
    • Lidofsky SD, Xie MH, Sostman A, Scharschmidt BF, Fitz JG. Vasopressin increases cytosolic sodium concentration in hepatocytes and activates calcium influx through cation-selective channels. J Biol Chem 1993;268:14632-6.
    • (1993) J Biol Chem , vol.268 , pp. 14632-14636
    • Lidofsky, S.D.1    Xie, M.H.2    Sostman, A.3    Scharschmidt, B.F.4    Fitz, J.G.5
  • 16
    • 0032522479 scopus 로고    scopus 로고
    • Increased beta-actin expression in an invasive moloney sarcoma virus-transformed MDCK cell variant concentrates to the tips of multiple pseudopodia
    • Le PU, Nguyen TN, Drolet-Savoie P, Leclerc N, Nabi IR. Increased beta-actin expression in an invasive moloney sarcoma virus-transformed MDCK cell variant concentrates to the tips of multiple pseudopodia. Cancer Res 1998;58:1631-5.
    • (1998) Cancer Res , vol.58 , pp. 1631-1635
    • Le, P.U.1    Nguyen, T.N.2    Drolet-Savoie, P.3    Leclerc, N.4    Nabi, I.R.5
  • 17
    • 0037073684 scopus 로고    scopus 로고
    • Autocrine activation of the hepatocyte growth factor receptor/met tyrosine kinase induces tumor cell motility by regulating pseudopodial protrusion
    • Vadnais J, Nault G, Daher Z, Amraei M, Dodier Y, Nabi IR, et al. Autocrine activation of the hepatocyte growth factor receptor/met tyrosine kinase induces tumor cell motility by regulating pseudopodial protrusion. J Biol Chem 2002;277:48342-50.
    • (2002) J Biol Chem , vol.277 , pp. 48342-48350
    • Vadnais, J.1    Nault, G.2    Daher, Z.3    Amraei, M.4    Dodier, Y.5    Nabi, I.R.6
  • 18
    • 0030761370 scopus 로고    scopus 로고
    • Insulin stimulated Glycogen synthesis in isolated rat hepatocytes: Effet of protein kinase inhibitors
    • Carlsen J, Christiansen K, Vinten J. Insulin stimulated Glycogen synthesis in isolated rat hepatocytes: Effet of protein kinase inhibitors. Cell Signal 1997;9:447-50.
    • (1997) Cell Signal , vol.9 , pp. 447-450
    • Carlsen, J.1    Christiansen, K.2    Vinten, J.3
  • 20
    • 0034492753 scopus 로고    scopus 로고
    • Antidiabetogenic activity of oleanolic acid glycosides from medicinal foodstuffs
    • Yoshikawa M, Matsuda H. Antidiabetogenic activity of oleanolic acid glycosides from medicinal foodstuffs. Biofactors 2000;13:231-7.
    • (2000) Biofactors , vol.13 , pp. 231-237
    • Yoshikawa, M.1    Matsuda, H.2
  • 21
    • 0031666786 scopus 로고    scopus 로고
    • Antidiabetic principles of natural medicines. III. Structure-related inhibitory activity and action mode of oleanolic acid glycosides on hypoglycemic activity
    • Matsuda H, Li Y, Murakami T, Matsumura N, Yamahara J, Yoshikawa M. Antidiabetic principles of natural medicines. III. Structure-related inhibitory activity and action mode of oleanolic acid glycosides on hypoglycemic activity. Chem Pharm Bull (Tokyo) 1998;46:1399-403.
    • (1998) Chem Pharm Bull (Tokyo) , vol.46 , pp. 1399-1403
    • Matsuda, H.1    Li, Y.2    Murakami, T.3    Matsumura, N.4    Yamahara, J.5    Yoshikawa, M.6
  • 22
    • 0033016945 scopus 로고    scopus 로고
    • Structure-related inhibitory activity of oleanolic acid glycosides on gastric emptying in mice
    • Matsuda H, Li Y, Murakami T, Yamahara J, Yoshikawa M. Structure-related inhibitory activity of oleanolic acid glycosides on gastric emptying in mice. Bioorg Med Chem 1999;7:323-7.
    • (1999) Bioorg Med Chem , vol.7 , pp. 323-327
    • Matsuda, H.1    Li, Y.2    Murakami, T.3    Yamahara, J.4    Yoshikawa, M.5
  • 25
    • 15444372472 scopus 로고    scopus 로고
    • Secondary metabolites from Argania spinosa (L.) Skeels
    • Charrouf Z, Guillaume D. Secondary metabolites from Argania spinosa (L.) Skeels. Phytochem Rev 2002b;1:345-54.
    • (2002) Phytochem Rev , vol.1 , pp. 345-354
    • Charrouf, Z.1    Guillaume, D.2
  • 26
    • 22144446826 scopus 로고    scopus 로고
    • Secondary metabolites ofargan tree (Morocco) may have disease prevention properties
    • Khallouki F, Spiegelhalder B, Bartsch H, Owen RW. Secondary metabolites ofargan tree (Morocco) may have disease prevention properties. Afr. J. Boitechnol 2005;4:381-88.
    • (2005) Afr. J. Boitechnol , vol.4 , pp. 381-388
    • Khallouki, F.1    Spiegelhalder, B.2    Bartsch, H.3    Owen, R.W.4
  • 27
    • 3342944401 scopus 로고    scopus 로고
    • Naringenin inhibits glucose uptake in MCF-7 breast cancer cells: A mechanism for impaired cellular proliferation
    • Harmon AW, Patel YM. Naringenin inhibits glucose uptake in MCF-7 breast cancer cells: a mechanism for impaired cellular proliferation. Breast Cancer Res Treat 2004;85:103-10.
    • (2004) Breast Cancer Res Treat , vol.85 , pp. 103-110
    • Harmon, A.W.1    Patel, Y.M.2
  • 28
    • 4444331025 scopus 로고    scopus 로고
    • Activation of protein kinase C betaII/epsilon-c-Jun NH2-terminal kinase pathway and inhibition of mitogen-activated protein/extracellular signal-regulated kinase 1/2 phosphorylation in antitumor invasive activity induced by the polymethoxy flavonoid, nobiletin
    • Miyata Y, Sato T, Yano M, Ito A. Activation of protein kinase C betaII/epsilon-c-Jun NH2-terminal kinase pathway and inhibition of mitogen-activated protein/extracellular signal-regulated kinase 1/2 phosphorylation in antitumor invasive activity induced by the polymethoxy flavonoid, nobiletin. Mol Cancer Ther 2004;3:839-47.
    • (2004) Mol Cancer Ther , vol.3 , pp. 839-847
    • Miyata, Y.1    Sato, T.2    Yano, M.3    Ito, A.4
  • 29
    • 0033394912 scopus 로고    scopus 로고
    • Dietary polyunsaturated fatty acids and cancers of the breast and colorectum: Emerging evidence for their role as risk modifiers
    • Bartsch H, Nair J, Owen RW. Dietary polyunsaturated fatty acids and cancers of the breast and colorectum: emerging evidence for their role as risk modifiers. Carcinogenesis 1999;20:2209-18.
    • (1999) Carcinogenesis , vol.20 , pp. 2209-2218
    • Bartsch, H.1    Nair, J.2    Owen, R.W.3
  • 30
    • 0036336583 scopus 로고    scopus 로고
    • Exocyclic DNA adducts as oxidative stress markers in colon carcinogenesis: Potential role of lipid peroxidation, dietary fat and antioxidants
    • Bartsch H, Nair J, Owen RW. Exocyclic DNA adducts as oxidative stress markers in colon carcinogenesis: potential role of lipid peroxidation, dietary fat and antioxidants. Biol Chem 2002;383:915-21.
    • (2002) Biol Chem , vol.383 , pp. 915-921
    • Bartsch, H.1    Nair, J.2    Owen, R.W.3
  • 31
    • 0031956424 scopus 로고    scopus 로고
    • PD98059 is an equipotent antagonist of the aryl hydrocarbon receptor and inhibitor of mitogen-activated protein kinase kinase
    • Reiners JJ Jr, Lee JY, Clift RE, Dudley DT, Myrand SP. PD98059 is an equipotent antagonist of the aryl hydrocarbon receptor and inhibitor of mitogen-activated protein kinase kinase. Mol Pharmacol 1998;53:438-45.
    • (1998) Mol Pharmacol , vol.53 , pp. 438-445
    • Reiners Jr., J.J.1    Lee, J.Y.2    Clift, R.E.3    Dudley, D.T.4    Myrand, S.P.5
  • 32
    • 14044273131 scopus 로고    scopus 로고
    • Antiproliferative and apoptotic effects of selective phenolic acids on T47D human breast cancer cells: Potential mechanisms of action
    • Kampa M, Alexaki VI, Notas G, Nifli AP, Nistikaki A, Hatzoglou A, et al. Antiproliferative and apoptotic effects of selective phenolic acids on T47D human breast cancer cells: potential mechanisms of action. Breast Cancer Res 2004;6:R63-R74.
    • (2004) Breast Cancer Res , vol.6
    • Kampa, M.1    Alexaki, V.I.2    Notas, G.3    Nifli, A.P.4    Nistikaki, A.5    Hatzoglou, A.6
  • 34
    • 0036884117 scopus 로고    scopus 로고
    • Gamma-tocopherol inhibits human cancer cell cycle progression and cell proliferation by down-regulation of cyclins
    • Gysin R, Azzi A, Visarius T. Gamma-tocopherol inhibits human cancer cell cycle progression and cell proliferation by down-regulation of cyclins. Faseb J 2002;16:1952-4.
    • (2002) Faseb J , vol.16 , pp. 1952-1954
    • Gysin, R.1    Azzi, A.2    Visarius, T.3
  • 35
    • 0034633629 scopus 로고    scopus 로고
    • Gamma-tocopherol and its major metabolite, in contrast to alpha-tocopherol, inhibit cyclooxygenase activity in macrophages and epithelial cells
    • Jiang Q, Elson-Schwab I, Courtemanche C, Ames BN. gamma-tocopherol and its major metabolite, in contrast to alpha-tocopherol, inhibit cyclooxygenase activity in macrophages and epithelial cells. Proc Natl Acad Sci U S A 2000;97:11494-9.
    • (2000) Proc Natl Acad Sci U S A , vol.97 , pp. 11494-11499
    • Jiang, Q.1    Elson-Schwab, I.2    Courtemanche, C.3    Ames, B.N.4
  • 36
    • 0034108379 scopus 로고    scopus 로고
    • Experimental basis for cancer prevention by vitamin E
    • Shklar G, Oh SK. Experimental basis for cancer prevention by vitamin E. Cancer Invest 2000;18:214-22.
    • (2000) Cancer Invest , vol.18 , pp. 214-222
    • Shklar, G.1    Oh, S.K.2
  • 37
    • 14944372178 scopus 로고    scopus 로고
    • Cellular and molecular effects of alpha-tocopheryloxybutyrate: Lessons for the design of vitamin e analog for cancer prevention
    • Wu Y, Zu K, Ni J, Yeh S, Kasi D, James NS, et al. Cellular and molecular effects of alpha-tocopheryloxybutyrate: lessons for the design of vitamin E analog for cancer prevention. Anticancer Res 2004;24:3795-802.
    • (2004) Anticancer Res , vol.24 , pp. 3795-3802
    • Wu, Y.1    Zu, K.2    Ni, J.3    Yeh, S.4    Kasi, D.5    James, N.S.6
  • 38
    • 0037082354 scopus 로고    scopus 로고
    • Roles of protein kinase C and alpha-tocopherol in regulation of signal transduction for GATA-4 phosphorylation in HL-1 cardiac muscle cells
    • Clement SA, Tan CC, Guo J, Kitta K, Suzuki YJ. Roles of protein kinase C and alpha-tocopherol in regulation of signal transduction for GATA-4 phosphorylation in HL-1 cardiac muscle cells. Free Radic Biol Med 2002;32:341-9.
    • (2002) Free Radic Biol Med , vol.32 , pp. 341-349
    • Clement, S.A.1    Tan, C.C.2    Guo, J.3    Kitta, K.4    Suzuki, Y.J.5
  • 39
    • 0022385083 scopus 로고
    • Plant anticancer agents: Schottenol glucosides from Bacharis cordifolia and Ipnosis aggregatta
    • Arizawa M, Kinghom A, Cordell G, Phebec C, Fansworth N. Plant anticancer agents: schottenol glucosides from Bacharis cordifolia and Ipnosis aggregatta. Planta medica 1985;6:544-5.
    • (1985) Planta Medica , vol.6 , pp. 544-545
    • Arizawa, M.1    Kinghom, A.2    Cordell, G.3    Phebec, C.4    Fansworth, N.5
  • 40
    • 0242362642 scopus 로고    scopus 로고
    • Sterol ferulates, sterols, and 5-alk(en)ylresorcinols from wheat, rye, and corn bran oils and their inhibitory effects on Epstein-Barr virus activation
    • Iwatsuki K, Akihisa T, Tokuda H, Ukiya M, Higashihara H, Mukainaka T, et al. Sterol ferulates, sterols, and 5-alk(en)ylresorcinols from wheat, rye, and corn bran oils and their inhibitory effects on Epstein-Barr virus activation. J Agric Food Chem 2003;51:6683-8.
    • (2003) J Agric Food Chem , vol.51 , pp. 6683-6688
    • Iwatsuki, K.1    Akihisa, T.2    Tokuda, H.3    Ukiya, M.4    Higashihara, H.5    Mukainaka, T.6
  • 42
    • 0034109445 scopus 로고    scopus 로고
    • Anticarcinogenicity potential of spinasterol isolated from squash flowers
    • Villasenor IM, Domingo AP. Anticarcinogenicity potential of spinasterol isolated from squash flowers. Teratog Carcinog Mutagen 2000;20:99-105.
    • (2000) Teratog Carcinog Mutagen , vol.20 , pp. 99-105
    • Villasenor, I.M.1    Domingo, A.P.2
  • 43
    • 4444384633 scopus 로고    scopus 로고
    • Spinasterol isolated from the root of Phytolacca americana and its pharmacological property on diabetic nephropathy
    • Jeong SI, Kim KJ, Choi MK, Keum KS, Lee S, Ahn SH, et al. alpha-Spinasterol isolated from the root of Phytolacca americana and its pharmacological property on diabetic nephropathy. Planta Med 2004;70:736-9.
    • (2004) Planta Med , vol.70 , pp. 736-739
    • Jeong, S.I.1    Kim, K.J.2    Choi, M.K.3    Keum, K.S.4    Lee, S.5    Ahn, S.H.6    Alpha-, E.A.7
  • 44
    • 3142676732 scopus 로고    scopus 로고
    • Lupeol modulates NF-kappaB and PI3K/Akt pathways and inhibits skin cancer in CD-1 mice
    • Saleem M, Afaq F, Adhami VM, Mukhtar H. Lupeol modulates NF-kappaB and PI3K/Akt pathways and inhibits skin cancer in CD-1 mice. Oncogene 2004;23:5203-14.
    • (2004) Oncogene , vol.23 , pp. 5203-5214
    • Saleem, M.1    Afaq, F.2    Adhami, V.M.3    Mukhtar, H.4
  • 45
    • 33748200964 scopus 로고    scopus 로고
    • Lupeol, a fruit and vegetable based triterpene, induces apoptotic death of human pancreatic adenocarcinoma cells via inhibition of Ras signaling pathway
    • in press
    • Saleem M, Kaur S, Kweon MH, Adhami VM, Afaq F, Mukhtar H. Lupeol, a fruit and vegetable based triterpene, induces apoptotic death of human pancreatic adenocarcinoma cells via inhibition of Ras signaling pathway. Carcinogenesis 2006; in press.
    • (2006) Carcinogenesis
    • Saleem, M.1    Kaur, S.2    Kweon, M.H.3    Adhami, V.M.4    Afaq, F.5    Mukhtar, H.6
  • 46
    • 0029947979 scopus 로고    scopus 로고
    • Effectiveness and safety of low-dose pravastatin and squalene, alone and in combination, in elderly patients with hypercholesterolemia
    • Chan P, Tomlinson B, Lee CB, Lee YS. Effectiveness and safety of low-dose pravastatin and squalene, alone and in combination, in elderly patients with hypercholesterolemia. J Clin Pharmacol 1996;36:422-7.
    • (1996) J Clin Pharmacol , vol.36 , pp. 422-427
    • Chan, P.1    Tomlinson, B.2    Lee, C.B.3    Lee, Y.S.4
  • 47
    • 0031843397 scopus 로고    scopus 로고
    • Chemopreventive effect of squalene on colon cancer
    • Rao CV, Newmark HL, Reddy BS. Chemopreventive effect of squalene on colon cancer. Carcinogenesis 1998;19:287-90.
    • (1998) Carcinogenesis , vol.19 , pp. 287-290
    • Rao, C.V.1    Newmark, H.L.2    Reddy, B.S.3
  • 48
    • 0031469108 scopus 로고    scopus 로고
    • Squalene, olive oil, and cancer risk: A review and hypothesis
    • Newmark HL. Squalene, olive oil, and cancer risk: a review and hypothesis. Cancer Epidemiol Biomarkers Prev 1997;6:1101-3.
    • (1997) Cancer Epidemiol Biomarkers Prev , vol.6 , pp. 1101-1103
    • Newmark, H.L.1
  • 49
    • 0242299690 scopus 로고    scopus 로고
    • In vitro cytoprotective activity of squalene on a bone marrow versus neuroblastoma model of cisplatin-induced toxicity. implications in cancer chemotherapy
    • Das B, Yeger H, Baruchel H, Freedman MH, Koren G, Baruchel S. In vitro cytoprotective activity of squalene on a bone marrow versus neuroblastoma model of cisplatin-induced toxicity. implications in cancer chemotherapy. Eur J Cancer 2003;39:2556-65.
    • (2003) Eur J Cancer , vol.39 , pp. 2556-2565
    • Das, B.1    Yeger, H.2    Baruchel, H.3    Freedman, M.H.4    Koren, G.5    Baruchel, S.6
  • 51
    • 28644440646 scopus 로고    scopus 로고
    • Natural Health Products, Modulation of immune function and preventaion of chronic diseases. Evidence-based Complem
    • Haddad PS, Azar GA, Groom S, Boivin M. Natural Health Products, Modulation of immune function and preventaion of chronic diseases. Evidence-based Complem. Altern. Med. 2005;2:513-20.
    • (2005) Altern Med , vol.2 , pp. 513-520
    • Haddad, P.S.1    Azar, G.A.2    Groom, S.3    Boivin, M.4
  • 52
    • 25844471651 scopus 로고    scopus 로고
    • Maintenance of an efficient and equilibrated immune system through the novel use of natural health products: Synopsis of a symphosium. Evidence-based Complem
    • Haddad PS, Beauchamp G, Côté G, Boivin M. Maintenance of an efficient and equilibrated immune system through the novel use of natural health products: synopsis of a symphosium. Evidence-based Complem. Altern. Med. 2005;2:237-8.
    • (2005) Altern Med , vol.2 , pp. 237-238
    • Haddad, P.S.1    Beauchamp, G.2    Côté, G.3    Boivin, M.4


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