Contact dermatitis and bradycardia in a preterm infant given tetracaine 4% gel

Therapeutic Drug Monitoring

Volumn 28, Issue 3, 2006, Pages 291-294

  Taddio, Anna ^a   Lee, Charlene M ^b   Parvez, Boriana ^a   Koren, Gideon ^a   Shah, Vibhuti ^b  

^a HOSPITAL FOR SICK CHILDREN   (Canada)

^b MOUNT SINAI HOSPITAL   (Canada)

Author keywords

Adverse drug reaction; Infant newborn; Local anesthesia; Pain; Tetracaine

Indexed keywords

ADRENALIN; ATROPINE; TETRACAINE;

APPLICATION SITE ERYTHEMA; ARTICLE; BRADYCARDIA; CASE REPORT; CENTRAL VENOUS CATHETER; CLINICAL EXAMINATION; CLINICAL FEATURE; DESQUAMATION; HUMAN; HYPOCALCEMIA; IMPETIGO; IRRITANT DERMATITIS; NEWBORN; PREMATURITY; PREMEDICATION; PRIORITY JOURNAL; PUSTULE;

ADMINISTRATION, TOPICAL; ANESTHETICS, LOCAL; BRADYCARDIA; DERMATITIS, CONTACT; GELS; HUMANS; INFANT, NEWBORN; INFANT, PREMATURE; TETRACAINE;

EID: 33748195079     PISSN: 01634356     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.ftd.0000195615.92591.9c     Document Type: Article

References (24)

1. Taddio A, Gurguis MG, Koren G. Lidocaine-prilocaine cream versus tetracaine gel for procedural pain in children. Ann Pharmacother. 2002;36:687-692.
2. Jain A, Rutter N. Topical amethocaine gel in the newborn infant: how soon does it work and how long does it last? Arch Dis Child Fetal Neonatal Ed. 2000;83:F211-F214.
3. Jain A, Rutter N. Does topical amethocaine gel reduce the pain of venepuncture in newborn infants? A randomised double blind controlled trial. Arch Dis Child Fetal Neonatal Ed. 2000;83:F207-F210.
4. Jain A, Rutter N. Local anaesthetic effect of topical amethocaine gel in neonates: randomised controlled trial. Arch Dis Child Fetal Neonatal Ed. 2000;82:F42-F45.
5. Jain A, Rutter N, Ratnayaka M. Topical amethocaine gel for pain relief of heel prick blood sampling: a randomised double blind controlled trial. Arch Dis Child Fetal Neonatal Ed. 2001;84:F56-F59.
6. Moore J. No more tears: a randomized controlled double-blind trial of Amethocaine gel vs. placebo in the management of procedural pain in neonates. J Adv Nurs. 2001;34:475-482.
7. Ballantyne M, McNair C, Ung E, et al. A randomized controlled trial evaluating the efficiency of tetracaine gel for pain relief from peripherally inserted central catheters in infants. Adv Neonatal Care. 2003;3:297-307.
8. Patel A, Czerniawski B, Gray S, et al. Does topical amethocaine gel reduce pain from heel prick blood sampling in premature infants? A randomized double-blind cross-over controlled study. Paediatr Child Health. 2003;8:222-225.
9. Long CP, McCafferty DF, Sittlington NM, et al. Randomized trial of novel tetracaine patch to provide local anaesthesia in neonates undergoing venepuncture. Br J Anaesth. 2003;91:514-518.
10. Johnston CC, Collinge JM, Henderson SJ, et al. A cross-sectional survey of pain and pharmacological analgesia in Canadian neonatal intensive care units. Clin J Pain. 1997;13:308-312.
11. Porter FL, Anand KJ, McIntosh N, et al. Epidemiology of pain in neonates. Res Clin Forums. 1998;20:9-18.
12. Stevens BJ, Franck LS. Assessment and management of pain in neonates. Paediatr Drugs. 2001;3:539-558.
13. Taddio A, Katz J, Ilersich AL, et al. Effect of neonatal circumcision on pain response during subsequent routine vaccination. Lancet. 1997;349:599-603.
14. Grunau RE. Long-term consequences of pain in human neonates. In: Anand KJ, Stevens BJ, McGrath PJ, eds. Pain in Neonates. 2nd ed. Amsterdam: Elsevier Science; 2000:55-74.
15. Naranjo CA, Busto U, Sellers EM, et al. A method for estimating the probability of adverse drug reactions. Clin Pharmacol Ther. 1981;30:239-245.
16. Ng E, Klinger G, Shah V, et al. Safety of benzodiazepines in newborns. Ann Pharmacother. 2002;36:1150-1155.
17. Gunter JB. Benefit and risks of local anesthetics in infants and children. Paediatr Drugs. 2002;4:649-672.
18. Anderson PO, Knoben JE, Troutman WG, eds. Handbook of Clinical Drug Data. 9th ed. Stamford, CT: Appleton and Lange; 1999.
19. Mazumdar B, Tomlinson AA, Faulder GC. Preliminary study to assay plasma amethocaine concentrations after topical application of a new local anaesthetic cream containing amethocaine. Br J Anaesth. 1991;67:432-436.
20. Woolfson AD, McCafferty DF, Boston V. Clinical experiences with a novel percutaneous amethocaine preparation: prevention of pain due to venepuncture in children. Br J Clin Pharmacol. 1990;30:273-279.
21. Lawson RA, Smart NG, Gudgeon AC, et al. Evaluation of an amethocaine gel preparation for percutaneous analgesia before venous cannulation in children. Br J Anaesth. 1995;75:282-285.
22. McCafferty DF, Woolfson AD, Boston V. In vivo assessment of percutaneous local anaesthetic preparations. Br J Anaesth. 1989;62:17-21.
23. Wongprasartsuk P, Main BJ. Adverse local reactions to amethocaine cream-audit and case reports. Anaesth Intensive Care. 1998;26:312-314.
24. O'Brien L, Taddio A, Lyszkiewicz D, et al. A critical review of the topical local anaesthetic amethocaine (Ametop) for pediatric pain. Paediatr Drugs. 2005;7:41-54.