Effect of oxidation of αA- and αB-crystallins on their structure, oligomerization and chaperone function

Molecular and Cellular Biochemistry

Volumn 288, Issue 1-2, 2006, Pages 125-134

  Rajan, Shanthi ^a   Horn, Chad ^a   Abraham, Edathara C ^a  

^a UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

Author keywords

Alpha crystallin oxidation; Hydroxyl radical; Molecular chaperones; Oligomeric structure disintegration; Protein structure; Secondary structure; Tertiary structure

Indexed keywords

ALCOHOL DEHYDROGENASE; ALPHA CRYSTALLIN; CHAPERONE; HYDROGEN PEROXIDE; INSULIN; RECOMBINANT PROTEIN;

ALPHA HELIX; ARTICLE; BETA SHEET; CIRCULAR DICHROISM; CONTROLLED STUDY; ENZYME ASSAY; ESCHERICHIA COLI; GEL PERMEATION CHROMATOGRAPHY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MOLECULAR WEIGHT; NONHUMAN; OLIGOMERIZATION; OXIDATION; PROTEIN EXPRESSION; PROTEIN FOLDING; PROTEIN FUNCTION; PROTEIN PURIFICATION; PROTEIN SECONDARY STRUCTURE; PROTEIN STRUCTURE; PROTEIN TARGETING; PROTEIN TERTIARY STRUCTURE; STATISTICAL SIGNIFICANCE; ANIMAL; CHEMISTRY; METABOLISM; OXIDATION REDUCTION REACTION; PROTEIN CONFORMATION; RAT; STRUCTURE ACTIVITY RELATION;

ALPHA-CRYSTALLIN A CHAIN; ALPHA-CRYSTALLIN B CHAIN; ANIMALS; CIRCULAR DICHROISM; HYDROGEN PEROXIDE; OXIDATION-REDUCTION; PROTEIN CONFORMATION; RATS; RECOMBINANT PROTEINS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 33748191276     PISSN: 03008177     EISSN: 15734919     Source Type: Journal    
DOI: 10.1007/s11010-006-9128-4     Document Type: Article

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