Cytokines and chemokines in cerebrospinal fluid and serum of adult patients with acute disseminated encephalomyelitis

Journal of the Neurological Sciences

Volumn 247, Issue 2, 2006, Pages 202-207

  Franciotta, Diego ^a   Zardini, Elisabetta ^a   Ravaglia, Sabrina ^b   Piccolo, Giovanni ^b   Andreoni, Laura ^a   Bergamaschi, Roberto ^b   Romani, Alfredo ^b   Tavazzi, Eleonora ^b   Naldi, Paola ^c   Ceroni, Mauro ^d   Marchioni, Enrico ^b  

^a UNIVERSITY OF PAVIA   (Italy)

^b C MONDINO NATIONAL NEUROLOGICAL INSTITUTE   (Italy)

^c MAGGIORE DELLA CARITÀ HOSPITAL   (Italy)

^d Policlinico di Monza   (Italy)

Author keywords

Acute disseminated encephalomyelitis; Cerebrospinal fluid; Chemokines; Cytokines; Inflammation; Multiple sclerosis

Indexed keywords

CCL1 CHEMOKINE; CCL22 CHEMOKINE; CHEMOKINE; CXCL1 CHEMOKINE; CXCL7 CHEMOKINE; CYTOKINE; GAMMA INTERFERON INDUCIBLE PROTEIN 10; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; RANTES; THYMUS AND ACTIVATION REGULATED CHEMOKINE; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; CHEMOLUMINESCENCE; CLINICAL ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; ENCEPHALOMYELITIS; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMAN; INFLAMMATION; MALE; MONOCYTE; MULTIPLE SCLEROSIS; NEUTROPHIL; PLEOCYTOSIS; POSTINFECTION ENCEPHALITIS; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN CEREBROSPINAL FLUID LEVEL; TH1 CELL; TH2 CELL; UPREGULATION;

ADULT; AGED; BLOTTING, WESTERN; CHEMOKINES; CYTOKINES; ENCEPHALOMYELITIS, ACUTE DISSEMINATED; FEMALE; HUMANS; MALE; MIDDLE AGED; STATISTICS, NONPARAMETRIC;

EID: 33748087797     PISSN: 0022510X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jns.2006.05.049     Document Type: Article

References (25)

1. Tselis A.C., and Lisak R.P. Acute disseminated encephalomyelitis. In: Antel J., Birnbaum G., and Hartung H.-P. (Eds). Clinical neuroimmunology (1998), Blackwell Science, Boston 116-147
2. Hartung H.-P., and Grossman R.I. ADEM. Distinct disease or part of the MS spectrum?. Neurology 56 (2001) 1257-1260
3. Bennetto L., and Scolding N. Inflammatory/post-infectious encephalomyelitis. J Neurol Neurosurg Psychiatry 75 Suppl. I (2004) i22-i28
4. 2 cytokines. Immunity 2 (1995) 271-279
5. Moser B., and Loetscher P. Lymphocyte traffic control by chemokines. Nat Immunol 2 (2001) 123-128
6. Dale R.C., and Morovat A. Interleukin-6 and oligoclonal IgG synthesis in children with acute disseminated encephalomyelitis. Neuropediatrics 34 (2003) 141-145
7. Ichiyama T., Shoji H., Kato M., Sawaishi Y., Ozawa H., Matsubara T., et al. Cerebrospinal fluid levels of cytokines and soluble tumour necrosis factor receptor in acute disseminated encephalomyelitis. Eur J Pediatr 161 (2002) 133-137
8. Leake J.A., Albani S., Kao A.S., Senac M.O., Billman G.F., Nespeca M.P., et al. Acute disseminated encephalomyelitis in childhood: epidemiologic, clinical and laboratory features. Pediatr Infect Dis J 23 (2004) 756-764
9. Yoshitomi T., Matsubara T., Nishikawa M., Katayama K., Ichiyama T., Hayashi T., et al. Increased peripheral blood interferon gamma-producing T cells in acute disseminated encephalomyelitis. J Neuroimmunol 111 (2000) 224-228
10. Bradley W.G., Daroff R.B., Fenichel G.M., and Marsden C. Neurology in clinical practice: principles of diagnosis and management (1995), Butterworth-Heinemann, Boston
11. McDonald W.I., Compston A., Edan G., Goodkin D., Hartung H.P., Lublin F.D., et al. Recommended diagnostic criteria for multiple sclerosis: guidelines from the International Panel on the diagnosis of multiple sclerosis. Ann Neurol 50 (2001) 121-127
12. Tibbling G., Link H., and Ohman S. Principles of albumin and IgG analysis in neurological disorders: I. Establishment of reference values. Scand J Clin Lab Invest 37 (1977) 385-390
13. Reiber H., and Felgenhauer K. Protein transfer at the blood cerebrospinal fluid barrier and the quantitation of the humoral immune response within the central nervous system. Clin Chim Acta 163 (1987) 319-328
14. Keir G., Luxton R.W., and Thompson E.J. Isoelectric focusing of cerebrospinal fluid immunoglobulin G: an annotated update. Ann Chem Biochem 27 (1990) 436-443
15. Schwarz S., Mohr A., Knauth M., Wildemann B., and Storch-Hagenlocher B. Acute disseminated encephalomyelitis. A follow-up study of 40 patients. Neurology 56 (2001) 1313-1318
16. Kadhim H., De Prez C., Gazagnes M.D., and Sebire G. In situ cytokine immune responses in acute disseminated encephalomyelitis: insights into pathophysiologic mechanisms. Hum Pathol 34 (2003) 293-297
17. Glabinski A.R., Tani M., Strieter R.M., Tuohy V.K., and Ransohoff R.M. Synchronous synthesis of alpha- and beta-chemokines by cells of diverse lineage in the central nervous system of mice with relapses of chronic experimental autoimmune encephalomyelitis. Am J Pathol 150 (1997) 617-630
18. Zehntner S.P., Brickman C., Bourbonniere L., Remington L., Caruso M., and Owens T. Neutrophils that infiltrate the central nervous system regulate T cell responses. J Immunol 174 (2005) 5124-5131
19. Gaupp S., Pitt D., Kuziel W.A., Cannella B., and Raine C.S. Experimental autoimmune encephalomyelitis (EAE) in CCR2(-/-) mice: susceptibility in multiple strains. Am J Pathol 162 (2003) 139-150
20. Hartl D., Griese M., Nicolai T., Zissel G., Prell C., Konstantopoulos N., et al. Pulmonary chemokines and their receptors differentiate children with asthma and chronic cough. J Allergy Clin Immunol 115 (2005) 728-736
21. Sebastiani S., Danelon G., Gerber B., and Uguccioni M. CCL22-induced responses are powerfully enhanced by synergy inducing chemokines via CCR4: evidence for the involvement of first beta-strand of chemokine. Eur J Immunol 35 (2005) 746-756
22. Lucchinetti C.F., Mandler R.N., McGavern D., Bruck W., Gleich G., Ransohoff R.M., et al. A role for humoral mechanisms in the pathogenesis of Devic's neuromyelitis optica. Brain 125 (2002) 1450-1461
23. Kivisakk P., Trebst C., Liu Z., Tucky B.H., Sorensen T.L., Rudick R.A., et al. T-cells in the cerebrospinal fluid express a similar repertoire of inflammatory chemokine receptors in the absence or presence of CNS inflammation: implications for CNS trafficking. Clin Exp Immunol 129 (2002) 510-518
24. Sørensen T.L., Tani M., Jensen J., Pierce V., Lucchinetti C., Folcik V.A., et al. Expression of specific chemokines and chemokine receptors in the central nervous system of multiple sclerosis patients. J Clin Invest 103 (1999) 807-815
25. Franciotta D., Martino G., Zardini E., Furlan R., Bergamaschi R., Andreoni L., et al. Serum and CSF levels of MCP-1 and IP-10 in multiple sclerosis patients with acute and stable disease and undergoing immunomodulatory therapies. J Neuroimmunol 115 (2001) 192-198