Synthesis of highly-functionalised pyridines via hetero-Diels-Alder methodology: reaction of 3-siloxy-1-aza-1,3-butadienes with electron deficient acetylenes

Tetrahedron

Volumn 62, Issue 23, 2006, Pages 5454-5463

  Fletcher, Matthew D ^a,b   Hurst, Timothy E ^b,c   Miles, Timothy J ^d   Moody, Christopher J ^b,c  

^a BANGOR UNIVERSITY   (United Kingdom)

^b UNIVERSITY OF EXETER   (United Kingdom)

^c UNIVERSITY OF NOTTINGHAM   (United Kingdom)

^d GLAXOSMITHKLINE   (United Kingdom)

Author keywords

Hetero Diels Alder reaction; Microwave irradiation; Pyridines

Indexed keywords

1 (BENZYLOXYCARBONYLMETHYLAMINO) 3 (TERT BUTYLDIMETHYLSILOXY) 2 METHYL 1 AZA 1,3 BUTANEDIENE; 1 BENZYLOXYCARBONYL 1 METHYLHYDRAZINE; 1,3 BUTADIENE; 3 (PIPERIDIN 1 YLIMINO)BUTAN 2 ONE; 3 (TERT BUTYLDIMETHYLSILOXY) 2 METHYL 1 PHTHALIMIDO 1 AZA 1,3 BUTANEDIENE; 3 (TERT BUTYLDIMETHYLSILOXY) 2 METHYL 1 PIPERIDINYL 1 AZA 1,3 BUTADIENE; 3 (TERT BUTYLDIPHENYLSILOXY) 1 (DIMETHYLAMINO) 2 METHYL 1 AZA 1,3 BUTADIENE; 3 SILOXY 1 AZA 1,3 BUTADIENE; ACETYLENE; HYDRAZONE DERIVATIVE; N BENZYLOXYCARBONYL N METHYLBUTANE 2,3 DIONE MONOHYDRAZONE; OXIME; OXYGEN; PYRIDINE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CYCLOADDITION; DIELS ALDER REACTION; DRUG STRUCTURE; DRUG SYNTHESIS; ELECTRON; IRRADIATION; METHODOLOGY; MICROWAVE RADIATION; PRIORITY JOURNAL; REACTION ANALYSIS; REACTION TIME; STRUCTURE ACTIVITY RELATION; SUBSTITUTION REACTION; SYNTHESIS;

BETULACEAE; TETRA;

EID: 33748057815     PISSN: 00404020     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tet.2006.03.051     Document Type: Article

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