Fetuses with congenital heart disease demonstrate signs of decreased cerebral impedance

American Journal of Obstetrics and Gynecology

Volumn 195, Issue 3, 2006, Pages 706-710

  Modena, Alisa ^a   Horan, Colleen ^a   Visintine, John ^a   Chanthasenanont, Athita ^b   Wood, Dennis ^a   Weiner, Stuart ^a  

^a THOMAS JEFFERSON UNIVERSITY   (United States)

^b THAMMASAT UNIVERSITY   (Thailand)

Author keywords

Cerebral autoregulation; Congenital heart defect; Middle cerebral artery

Indexed keywords

ARTICLE; BLOOD OXYGENATION; BRAIN BLOOD VESSEL; COMORBIDITY; CONGENITAL HEART DISEASE; CONTROL GROUP; CONTROLLED STUDY; DEVELOPMENTAL DISORDER; DISEASE MARKER; ECHOGRAPHY; FETUS; GESTATIONAL AGE; HEART DISEASE; HUMAN; HYPOXEMIA; IMPEDANCE CARDIOGRAPHY; MAJOR CLINICAL STUDY; MEDICAL RECORD REVIEW; MIDDLE CEREBRAL ARTERY; NERVOUS SYSTEM DEVELOPMENT; PRIORITY JOURNAL; PULSE WAVE; STATISTICAL ANALYSIS; STATISTICAL SIGNIFICANCE; THEORY;

CARDIOGRAPHY, IMPEDANCE; CEREBROVASCULAR CIRCULATION; FEMALE; FETAL DISEASES; HEART DEFECTS, CONGENITAL; HUMANS; MIDDLE CEREBRAL ARTERY; PREGNANCY; PULSATILE FLOW; RETROSPECTIVE STUDIES; ULTRASONOGRAPHY, DOPPLER; ULTRASONOGRAPHY, PRENATAL;

EID: 33747888619     PISSN: 00029378     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ajog.2006.05.045     Document Type: Article

References (18)

1. Wladimiroff J.W., Tonge H.M., and Stewart P.A. Doppler ultrasound assessment of cerebral blood flow in the human fetus. BJOG 93 (1986) 471-475
2. Galan H., Anthony R., Rigano S., Parker T., de Vrijer B., Ferrazzi E., et al. Fetal hypertension and abnormal Doppler velocimetry in an ovine model of intrauterine growth restriction. Am J Obstet Gynecol 192 (2005) 272-279
3. Baschat A., Gembruch U., Reiss I., Gortner L., Weiner C., and Harman C. Relationship between arterial and venous Doppler and perinatal outcome in fetal growth restriction. Ultrasound Obstet Gynecol 16 (2000) 407-413
4. Scherjon S., Smolders-DeHaas H., Kok J., and Zondervan H. The "brain-sparing" effect: antenatal cerebral Doppler findings in relation to neurologic outcome in very preterm infants. Am J Obstet Gynecol 169 (1993) 169-175
5. Chan F., Pun T., Lam P., Lam C., Lee C.P., and Lam Y. Fetal cerebral Doppler studies as a predictor of perinatal outcome and subsequent neurologic handicap. Obstet Gynecol 87 (1996) 981-988
6. Vyas S., Nicolaides K., Bower S., and Campbell S. Middle cerebral artery flow velocity waveforms in fetal hypoxaemia. BJOG 97 (1990) 797-803
7. Limperopoulos C., Majnemer A., Shevell M., Rosenblatt B., Rohlicek C., and Tchervenkov C. Neurologic status of newborns with congenital heart defects before open heart surgery. Pediatrics 103 (1999) 402-408
8. Limperopoulos C., Majnemer A., Shevell M., Rosenblatt B., Rohlicek C., and Tchervenkov C. Neurodevelopmental status of newborns and infants with congenital heart defects before and after open heart surgery. J Pediatr 137 (2000) 638-645
9. Glauser T.A., Rorke L.V., Weinberg P.M., and Clancy R.R. Congenital brain anomalies associated with the hypoplastic left heart syndrome. Pediatrics 85 (1990) 984-990
10. Rosenthal G., Wilson P., Permutt T., Boughman J., and Ferencz C. Birth weight and cardiovascular malformations: a population-based study: the Baltimore-Washington Infant study. Am J Epidemiol 133 (1991) 1273-1281
11. Donofrio M., Bremer Y., Schieken R., Gennings C., Morton L., and Eidem B. Autoregulation of cerebral blood flow in fetuses with congenital heart disease: the brain sparing effect. Pediatr Cardiol 24 (2003) 436-443
12. Chi J.G., Dooling E.C., and Gilles F.H. Gyral development of the human brain. Ann Neurol 1 (1977) 86-93
13. Gosling R.G., and King D.H. Arterial assessment by Doppler-shift ultrasound. Proc R Soc Med 67 (1974) 447-449
14. Maulik D. Hemodynamic interpretation of the arterial Doppler waveform. Ultrasound Obstet Gynecol 3 (1993) 219-227
15. Arduini D., and Rizzo G. Normal values of pulsatility index from fetal vessels: a cross-sectional study on 1556 healthy fetuses. J Perinat Med 18 (1990) 165-172
16. Bahado-Singh R., Kovanci E., Jeffres A., Oz U., Deren O., Copel J., et al. The Doppler cerebroplacental ratio and perinatal outcome in intrauterine growth restriction. Am J Obstet Gynecol 180 (1999) 750-756
17. Baschat A., and Gembruch U. The cerebroplacental Doppler ratio revisited. Ultrasound Obstet Gynecol 21 (2003) 124-127
18. Kaltman J., Tian H., and Rychik J. Impact of congenital heart disease on cerebrovascular blood flow dynamics in the fetus. Ultrasound Obstet Gynecol 25 (2005) 32-36