Acyl-Phosphates Initiate Membrane Phospholipid Synthesis in Gram-Positive Pathogens

Molecular Cell

Volumn 23, Issue 5, 2006, Pages 765-772

  Lu, Ying Jie ^a   Zhang, Yong Mei ^a   Grimes, Kimberly D ^b   Qi, Jianjun ^b   Lee, Richard E ^b   Rock, Charles O ^a  

^a ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

^b UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER   (United States)

Author keywords

MICROBIO

Indexed keywords

ACYLPHOSPHATASE; CARRIER PROTEIN; FATTY ACID; GLYCEROPHOSPHATE; PHOSPHATIDIC ACID; PHOSPHOLIPID;

ACYLATION; ARTICLE; BACTERIAL MEMBRANE; CATALYSIS; ESCHERICHIA COLI; FATTY ACID METABOLISM; GRAM POSITIVE BACTERIUM; PHOSPHOLIPID SYNTHESIS; PROTEIN LOCALIZATION; PROTEIN SYNTHESIS; PROTEIN TARGETING;

BACTERIAL PROTEINS; CELL MEMBRANE; ESCHERICHIA COLI; GLYCEROL-3-PHOSPHATE O-ACYLTRANSFERASE; PHOSPHATES; PHOSPHATIDYLINOSITOLS; PHOSPHOLIPIDS; STREPTOCOCCUS PNEUMONIAE;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI; POSIBACTERIA;

EID: 33747887074     PISSN: 10972765     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molcel.2006.06.030     Document Type: Article

References (35)

1. Badger J., Sauder J.M., Adams J.M., Antonysamy S., Bain K., Bergseid M.G., Buchanan S.G., Buchanan M.D., Batiyenko Y., Christopher J.A., et al. Structural analysis of a set of proteins resulting from a bacterial genomics project. Proteins 60 (2005) 787-796
2. m mutant. J. Bacteriol. 117 (1974) 1065-1076
3. m defective sn-glycerol-3-phosphate acyltransfersae activities. J. Biol. Chem. 250 (1975) 7147-7152
4. Black P.N., and DiRusso C.C. Transmembrane movement of exogenous long-chain fatty acids: proteins, enzymes, and vectorial esterification. Microbiol. Mol. Biol. Rev. 67 (2003) 454-472
5. Bradford M.M. A rapid and sensitive method for quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72 (1976) 248-254
6. Campbell J.W., and Cronan Jr. J.E. Escherichia coli FadR positively regulates transcription of the fabB fatty acid biosynthetic gene. J. Bacteriol. 183 (2001) 5982-5990
7. Coleman J. Characterization of the Escherichia coli gene for 1-acyl-sn-glycerol-3-phosphate acyltransferase (plsC). Mol. Gen. Genet. 232 (1992) 295-303
8. Cronan Jr. J.E. Molecular properties of short chain acyl thioesters of acyl carrier protein. J. Biol. Chem. 257 (1982) 5013-5017
9. Cronan Jr. J.E., and Rock C.O. Biosynthesis of membrane lipids. In: Neidhardt F.C., Curtis R., Gross C.A., Ingraham J.L., Lin E.C.C., Low K.B., Magasanik B., Reznikoff W., Riley M., Schaechter M., and Umbarger H.E. (Eds). Escherichia coli and Salmonella typhimurium: Cellular and Molecular Biology (1996), American Society for Microbiology, Washington, DC 612-636
10. Cronan Jr. J.E., and Subrahmanyam S. FadR, transcriptional co-ordination of metabolic expediency. Mol. Microbiol. 29 (1998) 937-943
11. Davis M.S., and Cronan Jr. J.E. Inhibition of Eschericia coli acetyl coenzyme A carboxylase by acyl-acyl carrier protein. J. Bacteriol. 183 (2001) 1499-1503
12. Green P.R., Merrill Jr. A.H., and Bell R.M. Membrane phospholipid synthesis in Escherichia coli: purification, reconstitution, and characterization of sn-glycerol-3-phosphate acyltransferase. J. Biol. Chem. 256 (1981) 11151-11159
13. Heath R.J., and Rock C.O. Inhibition of β-ketoacyl-acyl carrier protein synthase III (FabH) by acyl-acyl carrier protein in Escherichia coli. J. Biol. Chem. 271 (1996) 10996-11000
14. Heath R.J., and Rock C.O. A conserved histidine is essential for glycerolipid acyltransferase catalysis. J. Bacteriol. 180 (1998) 1425-1430
15. Heath R.J., and Rock C.O. A missense mutation accounts for the defect in the glycerol-3-phosphate acyltransferase expressed in the plsB26 mutant. J. Bacteriol. 181 (1999) 1944-1946
16. Heath R.J., Jackowski S., and Rock C.O. Guanosine tetraphosphate inhibition of fatty acid and phospholipid synthesis in Escherichia coli is relieved by overexpression of glycerol-3-phosphate acyltransferase (plsB). J. Biol. Chem. 269 (1994) 26584-26590
17. Holm L., and Park J. DaliLite workbench for protein structure comparison. Bioinformatics 16 (2000) 566-567
18. Ito K., Sato T., and Yura T. Synthesis and assembly of the membrane proteins in E. coli. Cell 11 (1977) 551-559
19. Jackowski S., Rettenmier C.W., Sherr C.J., and Rock C.O. A guanine nucleotide-dependent phosphatidylinositol 4,5- diphosphate phospholipase C in cells transformed by the v-fms and v-fes oncogenes. J. Biol. Chem. 261 (1986) 4978-4985
20. Jacobs M.A., Alwood A., Thaipisuttikul I., Spencer D., Haugen E., Ernst S., Will O., Kaul R., Raymond C., Levy R., et al. Comprehensive transposon mutant library of Pseudomonas aeruginosa. Proc. Natl. Acad. Sci. USA 100 (2003) 14339-14344
21. Kobayashi K., Ehrlich S.D., Albertini A., Amati G., Andersen K.K., Arnaud M., Asai K., Ashikaga S., Aymerich S., Bessieres P., et al. Essential Bacillus subtilis genes. Proc. Natl. Acad. Sci. USA 100 (2003) 4678-4683
22. Larson T.J., Ludtke D.N., and Bell R.M. sn-Glycerol-3-phosphate auxotrophy of plsB strains of Escherichia coli: evidence that a second mutation, plsX, is required. J. Bacteriol. 160 (1984) 711-717
23. Lehninger A.L. Synthesis and properties of the acyl phosphates of some higher fatty acids. J. Biol. Chem. 162 (1945) 333-342
24. Lightner V.A., Larson T.J., Tailleur P., Kantor G.D., Raetz C.R.H., Bell R.M., and Modrich P. Membrane phospholipid synthesis in Escherichia coli: cloning of a structural gene (plsB) of the sn-glycerol-3-phosphate acyltransferase. J. Biol. Chem. 255 (1980) 9413-9420
25. Lu Y.-J., and Rock C.O. Transcriptional regulation of fatty acid biosynthesis in Streptococcus pneumoniae. Mol. Microbiol. 59 (2006) 551-566
26. Polacco M.L., and Cronan Jr. J.E. Mechanism of the apparent regulation of Escherichia coli unsaturated fatty acid synthesis by exogenous oleic acid. J. Biol. Chem. 252 (1977) 5488-5490
27. Rock C.O., and Cronan Jr. J.E. Acyl-acyl carrier protein synthetase from Escherichia coli. Methods Enzymol. 71 (1981) 163-168
28. Rock C.O., and Garwin J.L. Preparative enzymatic synthesis and hydrophobic chromatography of acyl-acyl carrier protein. J. Biol. Chem. 254 (1979) 7123-7128
29. Rock C.O., and Jackowski S. Forty years of fatty acid biosynthesis. Biochem. Biophys. Res. Commun. 292 (2002) 1155-1166
30. Rock C.O., Cronan Jr. J.E., and Armitage I.M. Molecular properties of acyl carrier protein derivatives. J. Biol. Chem. 256 (1981) 2669-2674
31. Rock C.O., Goelz S.E., and Cronan Jr. J.E. Phospholipid synthesis in Escherichia coli. Characteristics of fatty acid transfer from acyl-acyl carrier protein to sn-glycerol-3-phosphate. J. Biol. Chem. 256 (1981) 736-742
32. Schujman G.E., Paoletti L., Grossman A.D., and de Mendoza D. FapR, a bacterial transcription factor involved in global regulation of membrane lipid biosynthesis. Dev. Cell 4 (2003) 663-672
33. Seyfzadeh M., Keener J., and Nomura M. spoT-dependent accumulation of guanosine tetraphosphate in response to fatty acid starvation in Escherichia coli. Proc. Natl. Acad. Sci. USA 90 (1993) 11004-11008
34. Xu Q.S., Jancarik J., Lou Y., Kuznetsova K., Yakunin A.F., Yokota H., Adams P., Kim R., and Kim S.-H. Crystal structures of a phosphotransacetylase from Bacillus subtilis and its complex with acetyl phosphate. J. Struct. Funct. Genomics 6 (2005) 269-279
35. Zhang Y.-M., Marrakchi H., and Rock C.O. The FabR (YijC) transcription factor regulates unsaturated fatty acid biosynthesis in Escherichia coli. J. Biol. Chem. 277 (2002) 15558-15565