Detection of potential drug interactions - A model for a national pharmacy register

European Journal of Clinical Pharmacology

Volumn 62, Issue 9, 2006, Pages 749-756

  Åstrand, Bengt ^a   Åstrand, Emelie ^b   Antonov, Karolina ^a   Petersson, Göran ^c  

^a Apoteket AB   (Sweden)

^b UPPSALA UNIVERSITY   (Sweden)

^c LINNAEUS UNIVERSITY   (Sweden)

Author keywords

Community pharmacy services; Decision making, computer assisted; Drug interactions; Drug therapy adverse effects; Drug utilization; Drug statistics and numerical data; Humans; Polypharmacy; Prescriptions; Sweden epidemiology

Indexed keywords

ANTICOAGULANT AGENT; BETA 2 ADRENERGIC RECEPTOR BLOCKING AGENT; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CALCIUM CHANNEL BLOCKING AGENT; DIGOXIN; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; DIURETIC AGENT; FUROSEMIDE; INSULIN; IPRATROPIUM BROMIDE; METFORMIN; METHOTREXATE; NONSTEROID ANTIINFLAMMATORY AGENT; ORAL ANTIDIABETIC AGENT; ORGANIC NITRATE; POTASSIUM SPARING DIURETIC AGENT; SILDENAFIL; VERAPAMIL; WARFARIN;

ADULT; AGE; AGED; ARTICLE; COHORT ANALYSIS; DRUG USE; FEMALE; HEALTH CARE PERSONNEL; HUMAN; MALE; PATIENT MONITORING; PHARMACY; POLYPHARMACY; PRESCRIPTION; PRIORITY JOURNAL; RISK ASSESSMENT; SWEDEN;

ADULT; AGED; AGED, 80 AND OVER; COMMUNITY PHARMACY SERVICES; DRUG INTERACTIONS; DRUG UTILIZATION; FEMALE; HUMANS; MALE; MIDDLE AGED; POLYPHARMACY; REGISTRIES; SWEDEN;

EID: 33747878322     PISSN: 00316970     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00228-006-0143-x     Document Type: Article

References (42)

1. Prop. 2004/05:70 Ökad patientsäkerhet på läkemedelsområdet (Improved patient safety within the pharmaceutical arena). Socialdepartementet (Swedish Ministry of Health and Social Affairs), http://www.regeringen.se/sb/d/108/a/38890 2004-07-01
2. Bergendal L, Friberg A, Schaffrath A (1995) Potential drugdrug interactions in 5,125 mostly elderly out-patients in Gothenburg, Sweden. Pharm World Sci 17:152-157
3. Bjerrum L, Andersen M, Petersen G, Kragstrup J (2003) Exposure to potential drug interactions in primary health care. Scand J Prim Health Care 21:153-158
4. Bjorkman IK, Fastbom J, Schmidt IK, Bernsten CB (2002) Drug-drug interactions in the elderly. Ann Pharmacother 36:1675-1681
5. Boethius G, Wiman F (1977) Recording of drug prescriptions in the county of Jamtland, Sweden. I. Methodological aspects. Eur J Clin Pharmacol 12:31-35
6. Cadieux RJ (1989) Drug interactions in the elderly. How multiple drug use increases risk exponentially. Postgrad Med 86:179-186
7. Chen YF, Avery AJ, Neil KE, Johnson C, Dewey ME, Stockley IH (2005) Incidence and possible causes of prescribing potentially hazardous/ contraindicated drug combinations in general practice. Drug Saf 28:67-80
8. Costa AJ (1991) Potential drug interactions in an ambulatory geriatric population. Fam Pract 8:234-236
9. Doucet J, Chassagne P, Trivalle C, Landrin I, Pauty MD, Kadri N, Menard JF, Bercoff E (1996) Drug-drug interactions related to hospital admissions in older adults: a prospective study of 1000 patients. J Am Geriatr Soc 44:944-948
10. Egger SS, Drewe J, Schlienger RG (2003) Potential drug-drug interactions in the medication of medical patients at hospital discharge. Eur J Clin Pharmacol 58:773-778
11. Goldberg RM, Mabee J, Chan L, Wong S (1996) Drug-drug and drug-disease interactions in the ED: analysis of a high-risk population. Am J Emerg Med 14:447-450
12. Gugler R, Allgayer H (1990) Effects of antacids on the clinical pharmacokinetics of drugs. An update. Clin Pharmacokinet 18:210-219
13. Hansten PD (2003) Drug interaction management. Pharm World Sci 25:94-97
14. Hardman JG, Limbird LE (2001) Goodman&Gilman's The Pharmacological Basis of Therapeutics 10th International edn. McGraw-Hill Professional, New York, pp 54-56
15. Haumschild MJ, Ward ES, Bishop JM, Haumschild MS (1987) Pharmacy-based computer system for monitoring and reporting drug interactions. Am J Hosp Pharm 44:345-348
16. Henry D, Dobson A, Turner C (1993) Variability in the risk of major gastrointestinal complications from nonaspirin nonsteroidal anti-inflammatory drugs. Gastroenterology 105:1078-1088
17. Jankel CA, Fitterman LK (1993) Epidemiology of drug-drug interactions as a cause of hospital admissions. Drug Saf 9:51-59
18. Juurlink DN, Mamdani M, Kopp A, Laupacis A, Redelmeier DA (2003) Drug-drug interactions among elderly patients hospitalized for drug toxicity. Jama 289:1652-1658
19. Koch-Weser J, Greenblatt DJ (1977) Drug interactions in clinical perspective. Eur J Clin Pharmacol 11:405-408
20. Kohler GI, Bode-Boger SM, Busse R, Hoopmann M, Welte T, Boger RH (2000) Drug-drug interactions in medical patients: effects of in-hospital treatment and relation to multiple drug use. Int J Clin Pharmacol Ther 38:504-513
21. Kurfees JF, Dotson RL (1987) Drug interactions in the elderly. J Fam Pract 25:477-488
22. Linnarsson R (1993) Drug interactions in primary health care. A retrospective database study and its implications for the design of a computerized decision support system. Scand J Prim Health Care 11:181-186
23. Lipton HL, Bero LA, Bird JA, McPhee SJ (1992) The impact of clinical pharmacists' consultations on physicians' geriatric drug prescribing. A randomized controlled trial. Med Care 30:646-658
24. Manchon ND, Bercoff E, Lemarchand P, Chassagne P, Senant J, Bourreille J (1989) [Incidence and severity of drug interactions in the elderly: a prospective study of 639 patients]. Rev Med Interne 10:521-525
25. Merlo J, Liedholm H, Lindblad U, Bjorck-Linne A, Falt J, Lindberg G, Melander A (2001) Prescriptions with potential drug interactions dispensed at Swedish pharmacies in January 1999: cross sectional study. Bmj 323:427-428
26. Molden E, Garcia BH, Braathen P, Eggen AE (2005) Coprescription of cytochrome P450 2D6/3A4 inhibitor-substrate pairs in clinical practice. A retrospective analysis of data from Norwegian primary pharmacies. Eur J Clin Pharmacol 61:119-125
27. Morera T, Gervasini G, Carrillo JA, Benitez J (2004) Early detection of drug interactions utilizing a computerized drug prescription handling system-focus on cerivastatin-gemfibrozil. Eur J Clin Pharmacol 59:917-921
28. Morera T, Gervasini G, Carrillo JA, Benitez J (2004) Using a computerized drug prescription screening system to trace drug interactions in an outpatient setting. Ann Pharmacother 38:1301-1306
29. Quinn D (1997) Clinically Important Drug Interactions. In: Speight TM, Holford N.H. (ed) Avery's Drug Treatment, 4th edn. ADIS International, Auckland, Philadelphia, pp 301-328
30. Rosholm JU, Bjerrum L, Hallas J, Worm J, Gram LF (1998) Polypharmacy and the risk of drug-drug interactions among Danish elderly. A prescription database study. Dan Med Bull 45:210-213
31. Rothman KJ (1986) Modern Epidemiology. Little, Brown, Boston, Toronto, p 37
32. Rupp MT, DeYoung M, Schondelmeyer SW (1992) Prescribing problems and pharmacist interventions in community practice. Med Care 30:926-940
33. Seymour RM, Routledge PA (1998) Important drug-drug interactions in the elderly. Drugs Aging 12:485-494
34. Sjöqvist F (1997) Fundamentals of Clinical Pharmacology. In: Speight TM, Holford N.H. (ed) Avery's Drug treatment, 4th edn. ADIS International, Auckland, Philadelphia, pp 52-53
35. Sjöqvist F (1997) A new classification system of drug interactions. Eur J Clin Pharmacol 52 (suppl.) Abstract 377
36. Stockley IH (2002) Stockley's Drug Interactions, 6 edn. The Pharmaceutical Press, London, p 1
37. Strom BL (1994) Adverse reactions to over-the-counter analgesics taken for therapeutic purposes. Jama 272:1866-1867
38. Tatro DS, Olin BR (1992) Drug Interaction Facts. Facts and Comparisons, 3rd edn. Lippincott, St Louis
39. W.H.O. ATC Index. W.H.O. (2005) Collaborating Centre for Drug Statistics Methodology, http://www.whocc.no/atcddd/07-20
40. Vestal RE, Norris AH, Tobin JD, Cohen BH, Shock NW, Andres R (1975) Antipyrine metabolism in man: influence of age, alcohol, caffeine, and smoking. Clin Pharmacol Ther 18:425-432
41. Whitcomb DC, Block GD (1994) Association of acetaminophen hepatotoxicity with fasting and ethanol use. Jama 272:1845-1850
42. Zhan C, Correa-de-Araujo R, Bierman AS, Sangl J, Miller MR, Wickizer SW, Stryer D (2005) Suboptimal prescribing in elderly outpatients: potentially harmful drug-drug and drug-disease combinations. J Am Geriatr Soc 53:262-267