Polypharmacy and the risk of drug-drug interactions among Danish elderly: A prescription database study

Danish Medical Bulletin

Volumn 45, Issue 2, 1998, Pages 210-213

  Rosholm, Jens Ulrik ^a,b   Bjerrum, Lars ^a   Hallas, Jesper ^a   Worm, Jørgen ^a   Gram, Lars F ^a  

^a ODENSE UNIVERSITY HOSPITAL   (Denmark)

^b UNIVERSITY OF SOUTHERN DENMARK   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIDIABETIC AGENT; ANTIVITAMIN K; ASTEMIZOLE; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CALCIUM CHANNEL BLOCKING AGENT; CARBAMAZEPINE; DEXTROPROPOXYPHENE; DIGOXIN; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; DIURETIC AGENT; ERYTHROMYCIN; FLUOXETINE; LITHIUM; METHOTREXATE; MONOAMINE OXIDASE INHIBITOR; NONSTEROID ANTIINFLAMMATORY AGENT; PETHIDINE; PHENOBARBITAL; QUINIDINE; SELEGILINE; SULFAMETHIZOLE; TERFENADINE; THIAZIDE DIURETIC AGENT; THYROID HORMONE; TRICYCLIC ANTIDEPRESSANT AGENT; VERAPAMIL;

ARTICLE; BLEEDING; CARDIOTOXICITY; COMA; COMBINATION CHEMOTHERAPY; DRUG ELIMINATION; DRUG METABOLISM; DRUG MONITORING; DRUG SAFETY; GERIATRIC CARE; HUMAN; HYPOGLYCEMIA; PRESCRIPTION;

AGED; DENMARK; DRUG INTERACTIONS; FEMALE; HUMANS; MALE; POLYPHARMACY; RETROSPECTIVE STUDIES; RISK FACTORS;

EID: 0031920857     PISSN: 09078916     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (20)

1. Holstein BE, Almind G, Due P, Holst E. Self-reported health status and drug use among the elderly (Ældres selvrapporterede helbred og lægemiddelforbrug). Ugeskr Laeger 1990; 152: 386-91.
2. Simons LA, Tett S, Simons J, Lauchlan R, McCallum J, Friedlander Y et al. Multiple medication use in the elderly. Use of prescription and non-prescription drugs in an Australian community setting. Med J Aust 1992; 157: 242-6.
3. Hendriksen C, Lund E, Strømgard E. Intake of drugs among elderly people in a Danish municipality, Rødovre. Acta Med Scand 1983; 214: 67-71.
4. Montamat SC, Cusack B. Overcoming problems with polypharmacy and drug misuse in the elderly. Clin Geriatr Med 1992; 8: 143-58.
5. Darnell JC, Murray MD, Martz BL, Weinberger M. Medication use by ambulatory elderly. An in-home survey. J Am Geriatr Soc 1986; 34: 1-4.
6. Lamy PP. The elderly and drug interactions. J Am Geriatr Soc 1986; 34: 586-92.
7. Stewart RB, Hale WE. Acute confusional states in older adults and the role of polypharmacy. Annu Rev Public Health 1992; 13: 415-30.
8. Klaukka T, Makela M, Sipila J, Martikainen J. Multiuse of medicines in Finland. Med Care 1993; 31: 445-50.
9. Need we poison the elderly so often? [editorial] Lancet 1988; 339: 20-2.
10. Hallas J, Hansen NCG. Individual utilization of anti-asthma medication by young adults: a prescription database analysis. J Intern Med 1993; 234: 65-70.
11. Bjerrum L, Rosholm JU, Hallas J, Kragstrup J. Methods for estimating the occurrence of polypharmacy by means of a prescription database. Eur J Clin Pharmacol 1997; 53: 7-11.
12. Hansten PD, Horn JR. Drug interactions and updates. Vancouver, Washington: Applied Therapeutics, 1994.
13. Guidelines for ATC classification and DDD assignment. Oslo: WHO Collaborating Centre for Drug Statistics Methodology, 1995.
14. Nolan L, O'Malley K. Prescribing for the elderly. Part I: Sensitivity of the elderly to adverse drug reactions. J Am Geriatr Soc 1988; 36: 142-9.
15. Schroll M. Geriatrics (Geriatri). In: Lorentzen I, Bendixen G, Hansen NE, eds. Medicinsk Kompendium. Copenhagen: Nyt Nordisk Forlag Arnold Busck, 1994; 2598-620.
16. Beers MB, Ouslander JG. Risk factors in geriatric drug prescribing. A practical guide to avoiding problems. Drugs 1989; 37: 105-12.
17. Colley CA, Lucas LM. Polypharmacy: the cure becomes the disease. J Gen Intern Med 1993; 8: 278-83.
18. Linnarsson R. Drug interactions in primary health care. Scand J Prim Health Care 1993; 11: 181-8.
19. Hallas J, Gram LF, Grodum E, Damsbo N, Brøsen K, Haghfeldt T et al. Drug related admissions to medical wards: a population based survey. Br J Clin Pharmacol 1992; 33: 61-8.
20. Ebbesen J, Baujordet I, Erikssen J, Svaar H, Brørs O. Hildberg T. Fatal drug reactions in medical inpatients (Legemidler som årsak til dødsfall). Nord Med 1995; 110: 250-2.