Selective dopamine D3 receptor antagonists enhance cortical acetylcholine levels measured with high-performance liquid chromatography/tandem mass spectrometry without anti-cholinesterases

Journal of Neuroscience Methods

Volumn 157, Issue 1, 2006, Pages 25-31

  Lacroix, Laurent P ^a   Ceolin, Laura ^a   Zocchi, Alessandro ^a   Varnier, Giorgia ^a   Garzotti, Marco ^a   Curcuruto, Ornella ^a   Heidbreder, Christian A ^a  

^a GSK   (Italy)

Author keywords

Acetylcholine; Dopamine D3 receptors; Medial prefrontal cortex; Microdialysis; SB 277011A; SB 414796A

Indexed keywords

ACETYLCHOLINE; CHOLINESTERASE INHIBITOR; DOPAMINE 3 RECEPTOR; DOPAMINE 3 RECEPTOR BLOCKING AGENT; SB 277011 A; SB 414796 A; UNCLASSIFIED DRUG; DOPAMINE RECEPTOR BLOCKING AGENT; FUSED HETEROCYCLIC RINGS; HYPOCHOLESTEROLEMIC AGENT; OXADIAZOLE DERIVATIVE; SB 414796A; SB-414796A;

ACETYLCHOLINE BRAIN LEVEL; ANALYTIC METHOD; AREA UNDER THE CURVE; ARTICLE; CONTROLLED STUDY; DRUG BRAIN LEVEL; DRUG EFFECT; EXTRACELLULAR MATRIX; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MALE; MICRODIALYSIS; NONHUMAN; PREFRONTAL CORTEX; PRIORITY JOURNAL; RAT; RELIABILITY; TANDEM MASS SPECTROMETRY; ANIMAL; BRAIN LEVEL; COMPARATIVE STUDY; DOSE RESPONSE; DRUG INTERACTION; EXTRACELLULAR SPACE; MASS SPECTROMETRY; METABOLISM; METHODOLOGY; SPRAGUE DAWLEY RAT;

ACETYLCHOLINE; ANIMALS; ANTICHOLESTEREMIC AGENTS; BRAIN CHEMISTRY; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DOPAMINE ANTAGONISTS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG INTERACTIONS; EXTRACELLULAR SPACE; HETEROCYCLIC COMPOUNDS, 2-RING; MALE; MASS SPECTROMETRY; MICRODIALYSIS; OXADIAZOLES; PREFRONTAL CORTEX; RATS; RATS, SPRAGUE-DAWLEY;

EID: 33747865765     PISSN: 01650270     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jneumeth.2006.03.017     Document Type: Article

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