Rationalization of physicochemical characters of 1,5-diarylpyrazole analogs as dual (COX-2/LOX-5) inhibitors: A QSAR approach

Journal of Pharmaceutical and Biomedical Analysis

Volumn 42, Issue 2, 2006, Pages 283-289

  Revathi, S ^a   Gupta, Arun Kumar ^a   Soni, Love Kumar ^a   Kavitha, S ^b   Wagh, R ^c   Kaskhedikar, S G ^a  

^a CADD Laboratory   (India)

^b Ultra College of Pharmacy   (India)

^c Institute of Pharmacy   (India)

Author keywords

COX 2; LOX 5; QSAR

Indexed keywords

CYCLOOXYGENASE 2 INHIBITOR; LIPOXYGENASE INHIBITOR; PYRAZOLE DERIVATIVE;

ANTIINFLAMMATORY ACTIVITY; ARTICLE; DRUG SAFETY; ELECTRON DIFFRACTION; HYDROPHILICITY; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; QUANTITATIVE STRUCTURE ACTIVITY RELATION;

ARACHIDONATE 5-LIPOXYGENASE; CYCLOOXYGENASE 2 INHIBITORS; LIPOXYGENASE INHIBITORS; MODELS, CHEMICAL; MOLECULAR STRUCTURE; PYRAZOLES; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP; REGRESSION ANALYSIS;

EID: 33747800358     PISSN: 07317085     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jpba.2006.04.020     Document Type: Article

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