Identification of new inhibitors of E. coli cyclopropane fatty acid synthase using a colorimetric assay

Biochimica et Biophysica Acta - Proteins and Proteomics

Volumn 1764, Issue 8, 2006, Pages 1381-1388

  Guianvarc'h, Dominique ^a   Drujon, Thierry ^a   Leang, Thearina Ear ^a   Courtois, Fabienne ^a   Ploux, Olivier ^a  

^a Centre National de la Recherche Scientifique   (France)

Author keywords

5,5 dithiobis 2 nitrobenzoic acid; Cyclopropane synthase; Homocysteine; Inhibitor screening; Spectrophotometric coupled assay

Indexed keywords

5,5' DITHIOBIS(2 NITROBENZOIC ACID); ADENOSINE DERIVATIVE; AMINE; CYCLOPROPANE FATTY ACID SYNTHASE INHIBITOR; CYCLOSINEFUNGIN; ENZYME INHIBITOR; HOMOCYSTEINE; NUCLEOSIDASE; OLEIC ACID; PALMITOLEIC ACID; QUATERNARY AMMONIUM DERIVATIVE; S ADENOSYLHOMOCYSTEINE; S RIBOSYLHOMOCYSTEINASE; SINEFUNGIN; TUBERCULOSTATIC AGENT; UNCLASSIFIED DRUG;

ARTICLE; CALORIMETRY; CHEMICAL PROCEDURES; CHEMICAL REACTION; DRUG IDENTIFICATION; DRUG SCREENING; ESCHERICHIA COLI; HIGH THROUGHPUT SCREENING; IC 50; MICROTITER PLATE ASSAY; PRIORITY JOURNAL; REACTION ANALYSIS;

COLORIMETRY; DRUG DESIGN; DRUG EVALUATION, PRECLINICAL; ENZYME INHIBITORS; ESCHERICHIA COLI K12; KINETICS; METHYLTRANSFERASES; MOLECULAR STRUCTURE; SPECTROPHOTOMETRY;

BACTERIA (MICROORGANISMS); MYCOBACTERIUM TUBERCULOSIS;

EID: 33747794608     PISSN: 15709639     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbapap.2006.06.002     Document Type: Article

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