Synthesis of new analogues of salacinol containing a pendant hydroxymethyl group as potential glycosidase inhibitors

Carbohydrate Research

Volumn 341, Issue 14, 2006, Pages 2305-2311

  Nasi, Ravindranath ^a   Pinto, B Mario ^a  

^a SIMON FRASER UNIVERSITY   (Canada)

Author keywords

Ammonium salt; Analogues of salacinol and ghavamiol; Cyclic sulfate; Glycosidase inhibitors; Sulfonium salt

Indexed keywords

ANALOGUES OF SALACINOL AND GHAVAMIOL; CYCLIC SULFATE; GLYCOSIDASE INHIBITORS; SULFONIUM SALTS;

CARBON; ENZYME INHIBITION; ENZYMES; NITROGEN COMPOUNDS; SALTS; SYNTHESIS (CHEMICAL);

ALCOHOLS;

1,3:4,6 DI O BENZYLIDINE 2,5 DIDEOXY 1,5 [[2,4 O BENZYLIDENE 2,4 DIHYDROXY 3 (SULFOOXY)BUTYL]SULFONIUMYLIDENE] LEVO IDITOL; 2,5 DIDEOXY 1,5 [[2,4 DIHYDROXY 3 (SULFOOXY)BUTYL]SULFONIUMYLIDENE] LEVO IDITOL; 2,5 DIDEOXY 2,5 IMINO 1,3:4,6 DI O BENZYLIDENE LEVO IDITOL; 2,5 DIDEOXY 2,5 N BENZYLIMINO 1,3:4,6 DI O BENZYLIDENE LEVO IDITOL; AMMONIUM DERIVATIVE; CARBOHYDRATE DERIVATIVE; GLYCOSIDASE; GLYCOSIDASE INHIBITOR; METHYL GROUP; SALACINOL; SALACINOL DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CARBOHYDRATE SYNTHESIS; DRUG POTENCY; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME ACTIVE SITE; PRIORITY JOURNAL; STEREOCHEMISTRY; STRUCTURE ACTIVITY RELATION;

ARABINOSE; CARBOHYDRATE SEQUENCE; ENZYME INHIBITORS; ERYTHRITOL; GLYCOSIDE HYDROLASES; IMINO FURANOSES; MOLECULAR STRUCTURE; QUATERNARY AMMONIUM COMPOUNDS; SUGAR ALCOHOLS; SULFATES;

EID: 33747792057     PISSN: 00086215     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.carres.2006.06.022     Document Type: Article

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