A new class of glucosidase inhibitor: Analogues of the naturally occurring glucosidase inhibitor salacinol with different ring heteroatom substituents and acyclic chain extension

Journal of Organic Chemistry

Volumn 71, Issue 8, 2006, Pages 3007-3013

  Liu, Hui ^a   Sim, Lyann ^b   Rose, David R ^b   Pinto, B Mario ^a  

^a SIMON FRASER UNIVERSITY   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

D-SORBITOL; DIABETES; GLUCOSIDASE INHIBITOR; SALACINOL; STEREOGENIC CENTERS;

ENZYMES; GLUCOSE; HYDROXYLATION; POTASH; STEREOCHEMISTRY; SULFUR COMPOUNDS; SYNTHESIS (CHEMICAL);

ENZYME INHIBITION;

ACARBOSE; ALPHA GLUCOSIDASE INHIBITOR; GLYCOSIDASE INHIBITOR; HEXAFLUORO 2 PROPANOL; KOTALANOL; OLIGOSACCHARIDE; POTASSIUM CARBONATE; SALACINOL; SWAINSONINE; UNCLASSIFIED DRUG;

ARTICLE; DEPROTECTION REACTION; DRUG SYNTHESIS; NON INSULIN DEPENDENT DIABETES MELLITUS; STEREOCHEMISTRY; STRUCTURE ACTIVITY RELATION;

ACIDS, ACYCLIC; ALPHA-GLUCOSIDASES; BIOLOGICAL PRODUCTS; ENZYME INHIBITORS; HETEROCYCLIC COMPOUNDS, 1-RING; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; MOLECULAR STRUCTURE; SUGAR ALCOHOLS; SULFATES;

EID: 33645794706     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo052539r     Document Type: Article

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