Respiratory and body temperature modulation by adenosine A1 receptors in the anteroventral preoptic region during normoxia and hypoxia

Respiratory Physiology and Neurobiology

Volumn 153, Issue 2, 2006, Pages 115-125

  Barros, Renata C H ^a   Branco, Luiz G S ^b   Cárnio, Evelin C ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

^b Faculdade de Odontologia de Ribeirao Preto   (Brazil)

Author keywords

Adenosine; Hypoxia; Preoptic Area; Rats; Thermoregulation; Ventilation

Indexed keywords

8 CYCLOPENTYL 1,3 DIPROPYLXANTHINE; ADENOSINE; ADENOSINE A1 RECEPTOR; ADENOSINE A1 RECEPTOR ANTAGONIST; AMINOPHYLLINE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTEROVENTRAL PREOPTIC REGION; ARTICLE; BODY TEMPERATURE; BRAIN REGION; BREATHING; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFECT; DRUG SELECTIVITY; HYPERVENTILATION; HYPOTHERMIA; HYPOXIA; MALE; METABOLIC REGULATION; NONHUMAN; OXYGEN BLOOD LEVEL; PREOPTIC AREA; PRIORITY JOURNAL; RAT; RESPIRATION CONTROL; THERMOREGULATION;

ADAPTATION, PHYSIOLOGICAL; ADENOSINE; AMINOPHYLLINE; ANALYSIS OF VARIANCE; ANIMALS; ANOXIA; BODY TEMPERATURE REGULATION; DOSE-RESPONSE RELATIONSHIP, DRUG; MALE; MICROINJECTIONS; PREOPTIC AREA; RATS; RATS, WISTAR; RECEPTOR, ADENOSINE A1; RESPIRATION; TIDAL VOLUME; XANTHINES;

EID: 33747778715     PISSN: 15699048     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.resp.2005.09.013     Document Type: Article

References (49)

1. Barros R.C.H., and Branco L.G.S. Role of central adenosine in the respiratory and thermoregulatory responses to hypoxia. NeuroReport 2 1 (2000) 193-197
2. Barros R.C.H., Zimmer M.E., Branco L.G.S., and Milsom W.K. Hypoxic metabolic response of the golden mantled ground squirrel. J. Appl. Physiol. 91 (2001) 603-612
3. Barros R.C.H., Branco L.G.S., and Cárnio E.C. Evidence for thermoregulation by dopamine D1 and D2 receptors in the anteroventral preoptic region during normoxia and hypoxia. Brain Res. 1030 2 (2004) 165-171
4. Bartlett Jr. D., and Tenney S.M. Control of breathing in experimental anemia. Respir. Physiol. 10 (1970) 384-395
5. Blood A.B., Hunter C.J., and Power G.G. Adenosine mediates decreased cerebral metabolic rate and increased cerebral blood flow during acute moderate hypoxia in the near-term fetal sheep. J. Physiol. 553 3 (2003) 935-945
6. 2 production at raised body temperature in rats. Exp. Physiol. 85 3 (2000) 309-319
7. Branco L.G.S., Cárnio E.C., and Barros R.C.H. Role of the nitric oxide pathway in hypoxia-induced hypothermia in rats. Am. J. Physiol. 273 (1997) 967-971
8. Collis M.G. The vasodilator role of adenosine. Pharmacol. Therapeutics 41 (1989) 143-162
9. Commission for Thermal Physiology of IUPS. 2001. Glossary of terms for Thermal Physiology. Jpn. J. Physiol. 51(2), 225-280.
10. De Paula P.M., and Machado B.H. Antagonism of adenosine A1 receptors in the NTS does not affect the chemoreflex in awake rats. Am. J. Physiol. Regul. Integr. Comp. Physiol. 281 6 (2001) R2072-R2078
11. Dejours P. Principles of Comparative Respiratory Physiology. second ed. (1981), Elsevier/North-Holland Biochemical Press, New York, NY, USA
12. Dillon G.H., and Waldrop T.G. Response of feline caudal hypothalamic cardiorespiratory neurons to hypoxia and hypercapnia. Exp. Brain Res. 96 (1993) 260-272
13. Dreshaj I.A., Haxhiu M.A., Martin R.J., and Young J.K. The basomedial hypothalamus modulates the ventilatory response to hypoxia in neonatal rats. Pediatr. Res. 53 (2003) 945-949
14. Dunwiddie T.V., and Fredholm B.B. Adenosine neuromodulation. Can. J. Physiol. Pharmacol. 72 (1997) 673-678
15. Easton P.A., and Anthonisen N.R. Ventilatory response to sustained hypoxia after pretreatment with aminophylline. J. Appl. Physiol. 64 (1988) 1445-1450
16. Evans M.H. Stimulation of the rabbit hypothalamus: caudal projections to respiratory and cardiovascular centres. J. Physiol. (Lond) 260 (1976) 205-222
17. Fredholm B.B., Ijzerman A.P., Jacobson K.A., Klotz K., and Linden J. International Union of Pharmacology. XXV. Nomenclature and classification of adenosine receptors. Pharmacol. Rev. 53 (2001) 527-552
18. Gargaglioni, L.H., Bícego, K.C., Nucci, T.B., Branco, L.G.S., 2005. Serotoninergic receptors into the anteroventral preoptic region modulate the hypoxic ventilatory response. Respir. Physiol. Biol., in press.
19. Gautier H., and Murariu C. Neuromodulators of hypoxic hypothermia in the rat. Respir. Physiol. 112 (1998) 315-324
20. Gershan W.M., Forster H.V., Lowry T.F., and Garber A.K. Effect of theophylline on ventilatory roll-off during hypoxia in goats. Respir. Physiol. 103 (1996) 157-164
21. Heymans C., Bouckaert J.J., and Bautrebande L. Sinus Carotidien et réflexes respiratoires. II. Influences respiratoires reflexes de l'acidose, de l'alcalose, de l'anhydride carbonique, de l'ion hydrogene et de l'anoxémie: Sinus carotidiens et changes respiratoires dans les pumons et au dela des poumons. Arch. Int. Pharmacodyn. Ther. 39 (1930) 400-408
22. Hinrichsen C.F.L.J., Maskrey M., and Mortola J.P. Ventilatory and metabolic responses to cold and hypoxia in conscious rats with discrete hypothalamic lesions. Respir. Physiol. 111 (1998) 247-256
23. Horn E.M., and Waldrop T.G. Modulation of the respiratory response to hypoxia and hypercapnia by synaptic input onto caudal hypothalamic neurons. Brain Res. 664 1-2 (1994) 25-33
24. Horn E.M., Dillon G.H., Fan Y.P., and Waldrop T.G. Development aspects and mechanisms of rat caudal hypothalamic neuronal responses to hypoxia. J. Neurophysiol. 81 4 (1999) 1949-1959
25. Iwase M., Izumizaki M., Kanamaru M., and Homma I. Involvement of central histaminergic neurons in polypnea induced by hyperthermia in rabbits. Neurosci. Lett. 298 (2001) 119-122
26. 2 use in fetal/neonatal sheep. J. Appl. Physiol. 81 (1996) 541-547
27. Koos B.J., Kruger L., and Murray T.F. Source of extracellular brain adenosine during hypoxia in fetal sheep. Brain Res. 778 (1997) 439-442
28. 2A receptor blockade abolishes the roll-off respiratory response to hypoxia in awake lambs. Am. J. Physiol. Regul. Integr. Comp. Physiol. 288 5 (2004) R1185-R1194
29. Lee T.F., Li D., Jacobson K.A., and Wang C.H. Improvement of cold tolerance by selective A1 adenosine receptor antagonists in rats. Pharmachol. Biochem. Behav. 37 (1990) 107-112
30. Long W.Q., and Anthonisen N.R. Aminophylline partially blocks ventilatory depression with hypoxia in the awake cat. Can. J. Physiol. Pharmacol. 72 (1994) 673-678
31. Magoun H.W., Harrison F., and Brobeck J.R. Activation of heat loss mechanisms by local heating of the brain. J. Neurophysiol. 1 (1938) 101-114
32. Malan A. Ventilation measured by body plethysmography in hibernating mammals and in poikilotherms. Respir. Physiol. 17 (1973) 32-44
33. Marshall J.M., and Metcalfe J.D. Analysis of the cardiovascular changes induced in the rat by graded levels of systemic hypoxia. J. Physiol. 407 (1988) 385-403
34. Maskrey M., and Hinrichsen C.F.L. Respiratory response to combined hypoxia and hypothermia in rats after posterior hypothalamic lesions. Pflüegers Arch. 426 (1994) 371-377
35. Neylon M., and Marshall J.M. The role of adenosine in the respiratory and cardiovascular response to systemic hypoxia in the rat. J. Physiol. 440 (1991) 529-545
36. Ni H., Schechtman V.L., Zhang J., Glotzbach S.F., and Harper R.M. Respiratory responses to preoptic/anterior hypothalamic warming during sleep in kittens. Reprod. Fertil. Dev. 8 1 (1996) 79-86
37. Paxinos G., and Watson C. The Rat Brain in Stereotaxic Coordinates. fourth ed. (1998), Academic, San Diego, CA
38. Redgate E.S. Hypothalamic influence on respiration. Ann. NY Acad. Sci. 109 (1963) 606-618
39. Rigatto H. Control of ventilation in the newborn. Ann. Rev. Physiol. 46 (1984) 661-674
40. Rudolphi K.A., Schubert P., Parkinson F.E., and Fredholm B.B. Neuroprotective role of adenosine in cerebral ischemia. Trends Pharmacol. Sci. 13 (1992) 439-445
41. Steiner A.A., Rocha M.J.A., and Branco L.G.S. A neurochemical mechanism for hypoxia-induced anapyrexia. Am. J. Physiol. Regul. Integr. Comp. Physiol. 283 (2002) R1412-R1422
42. Steiner A.A., Antunes-Rodrigues J., and Branco L.G.S. Role of preoptic second messenger system (cAMP and cGMP) in the febrile response. Brain Res. 944 1-2 (2002) 135-145
43. 2. Respir. Physiol. 29 (1977) 81-92
44. Ticho S.R., and Radulovacki M. Role of adenosine in sleep and temperature regulation in preoptic area of rats. Pharmacol. Biochem. Behav. 40 (1991) 33-40
45. Vizek M., Pickett C.K., and Weil J.V. Biphasic ventilatory response of adult cats to sustained hypoxia has central origin. J. Appl. Physiol. 63 (1987) 1658-1664
46. Wang X.L., Lee T.F., and Wang L.C.H. Do adenosine antagonists improve cold tolerance by reducing hypothalamic adenosine activity in rats?. Brain Res. Bull. 24 (1990) 389-391
47. Winn H.R., Rubio R., and Berne R.M. Brain adenosine concentration during hypoxia in rats. Am. J. Physiol. 241 (1981) H235-H242
48. Yarbrough G.G., and McGuffin-Clineschimidt J.C. In vivo behavioral assessment of central nervous system purinergic receptors. Eur. J. Pharmachol. 76 (1981) 137-144
49. Yelmen N.K., Turgut G., Sahin G., and Oruc T. Effects of intravenous and intracerebroventricular theophylline on hypoxic ventilatory depression in anesthetized cats. Med. Princ. Pract. 13 5 (2004) 277-281