Characteristics of T-cell immunity in patients with acute leukemia

Terapevticheskii Arkhiv

Volumn 78, Issue 7, 2006, Pages 18-25

  Parovichnikova, E N ^a   Galtseva, I V ^a   Vorobyev, I A ^a   Savchenko, V G ^a  

^a NONE

Author keywords

Acute leukemias; Antitumor immunity; T cell immune response

Indexed keywords

CYTOKINE; LEUKOCYTE ANTIGEN;

ACUTE DISEASE; ADOLESCENT; ADULT; ARTICLE; BIOSYNTHESIS; BLOOD; CELLULAR IMMUNITY; FEMALE; FLOW CYTOMETRY; HUMAN; IMMUNOLOGY; LEUKEMIA; MALE; METABOLISM; MIDDLE AGED; T LYMPHOCYTE; TH1 CELL; TH2 CELL;

ACUTE DISEASE; ADOLESCENT; ADULT; ANTIGENS, CD; CYTOKINES; FEMALE; FLOW CYTOMETRY; HUMANS; IMMUNITY, CELLULAR; LEUKEMIA; MALE; MIDDLE AGED; T-LYMPHOCYTES; TH1 CELLS; TH2 CELLS;

EID: 33747777120     PISSN: 00403660     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (35)

1. Fefer A., Sullivan K. M., Weiden P. Graft versus leukemia effect in man: the relapse rate of acute leukemia is lower after allogeneic than after syngeneic marrow transplantation. Progr. Clin. Biol. Res. 1987; 244: 401-408.
2. Champlin R. T-cell depletion for bone marrow transplantation: effects on graft rejection, graft-versus-host disease, graft-versus-leukemia, and survival. Cancer Treat. Res. 1990; 50: 99-111.
3. Foa R. Interleukin 2 in the management of acute leukaemia. Br. J. Haematol. 1996; 92 (1): 1-8.
4. Velders M. P., ter Horst S. A. J., Kast W. M. Prospects of immunotherapy of acute lymphoblastic leukemia. Leukemia 2002; 15: 7001-706.
5. Zhang X-Li, Komada Y., Chipeta J. et al. Intracellular cytokine profile of T cells from children with acute lymphoblastic leukemia. Cancer Immunol. Immunother. 2000; 49: 165-172.
6. Arpinati M., Green C. L., Heimfeld S. et al. Granulocyte-colony stimulating factor mobilizes T helper 2-inducing dendritic cells. Blood 2000; 95 (8): 2484-2490.
7. Mosmann T. R., Li L., Sad S. Functions of CD8 T-cell subsets secreting different cytokine patterns. Semin. Immunol. 1997; 9: 87-92.
8. Loeffler C. M., Smith M. J., Longo D. L. et al. Immunoregulation in cancer-bearing hosts. Down-regulation of gene expression and cytotoxic function in CD8+ T cells. J. Immunol. 1992; 149: 949-961.
9. Bruserud O. Cellular immune responses in acute leukaemia patients with severe chemotherapy-induced leucopenia; charaterization of the cytokine repertoire of clonogenic T cells. Cancer Immunol. Immunother. 1998; 46 (4): 221-228.
10. Egeter O., Mocikat R., Ghoreschi K. et al. Eradication of disseminated lymphomas with CpG-DNA activated T helper type 1 cells from nontransgenic mice. Cancer Res. 2000; 60 (6): 1515-1520.
11. Nishimura T., Iwakabe K., Sekimoto M. et al. Distinct role of antigen-specific T helper type 1 (Th1) and Th2 cells in tumor eradication in vivo. J. Exp. Med. 1999; 190 (5): 617-627.
12. Tatsumi T., Kierstead L. S., Ranieri E. et al. Disease-associated bias in Th helper type 1 (Th1)/Th2 CD4(+) T cell responses against MAGE-6 in HLA-DRB10401 (+) patients with renal cell carcinoma or melanoma. J. Exp. Med. 2002; 196 (5): 619-628.
13. Lee P. P., Zheng D., Mccaulay A. E. et al. T helper 2 - dominant antilymphoma immune response is associated with fatal outcome. Blood 1997; 90 (4): 1611-1617.
14. Nakayama H., Kitayama J., Muto T. et al. Characterization of intracellular cytokine profile of CD4(+) T cells in peripheral blood and tumor-draining lymph nodes of patients with gastrointestinal cancer. Clin. Oncol. 2000; 30: 301.
15. Pellegrini P., Berghella A. M., Beato T. D. et al. Disregulation in Th1 and Th2 subsets of CD4+ T cells in peripheral blood of colorectal cancer patients and involvement in cancer establishment and progression. Cancer Immunol. Immunother. 1996; 42: 1-11.
16. Kim J., Modlin R. L., Moy R. L. et al. IL-10 production in cutaneous basal and squamous cell carcinomas. A mechanism for evading the local T cell immune response. J. Immunol. 1995; 155 (4): 2240-2247.
17. Filella X., Alcover J., Zarco M. A. et al. Analysis of type T1 and T2 cytokines in patients with prostate cancer. Prostate 2000; 44: 271-274.
18. Yotnda P., Mintz P., Grigoriadou K. et al. Analysis of T-cell defects in the specific immune response against acute lymphoblastic leukemia cells. Exp. Hematol. 1999; 27: 1375.
19. Rossmann E., Levin N., Jeddi-Tehrani M. et al. Intracellular T cell cytokines in patients with B cell chronic lymphocytic leukaemia (B-CLL). Eur. J. Haematol. 2002; 68 (5): 299-306.
20. Reuben J. M., Lee B. N., Johnson H. et al. Restoration of Th1 cytokine synthesis by T cells of patients with chronic myelogenous leukemia in cytogenetic and hematologic remission with interferon α. Clin. Cancer Res. 2000; 6 (5): 1671-1677.
21. Kiani A., Habermann I., Schake K. et al. Normal intrinsic Th1/Th2 balance in patients with chronic phase chronic myeloid leukemia not treated with interferon-alpha or imatinib. Haematologica 2003; 88: 754.
22. Panoskaltsis N., Reid C. D. L., Knightet S. et al. Quantification of cytokine production of circulating and myeloid cells in acute myelogenous leukemia. Leukemia 2003; 17 (4): 716-730.
23. Galtzeva I., Parovitchnikova E. N., Sadovnikova E. Yu. et al. Th1 and Th2 cytokine production by T-cell from acute myeloid leukemia (AML) patients. Immunology 2004; abstr. book: 393-396.
24. Aspinall R., Andrew D. Thymic involution in aging. J. Clin. Immunol. 2000; 20 (4): 250-256.
25. Mackall C. L., Hakim F. T., Gres R. E. Restoration of T-cell homeostasis after T-cell depletion. Seminars. Immunology 1997; 9 (6): 339-346.
26. Pido-Lopez J., Imami N., Aspinall R. Both age and gender affect thymic output: more recent thymic migrants in females than males as they age. Clin. Exp. Immunol. 2001; 125 (3): 409-413.
27. Monteneiro J. P., Benjamin A., Costa E. S. et al. Normal hematopoiesis is maintained by activated bone marrow CB4+ cells. Blood 2005; 105 (4): 1484-1491.
28. Parlato S., Santini S. M., Lapenta C. et al. Expression of CCR-7, MIP-3beta, and Th-1 chemokines in type I IFN-induced monocyte-derived dendritic cells: importance for the rapid acquisition of potent migratory and functional activities. Blood 2001; 98 (10): 3022-3029.
29. Rissoan M. C., Soumelis V., Kadowaki N. et al. Reciprocal control of T helper cell and dendritic cell differentiation. Science 1999; 283: 1183-1187.
30. Siegal F.-P., Kadowaki N., Shodell M. et al. The nature of the principal type 1 interferon-producing cells in human blood. Science 1999; 284: 1835-1837.
31. Radvanyi L.-G., Banerjee A., Weir M., Messner H. Low levels of interferon-alpha induce CD86 (B7.2) expression and accelerates dendritic cell maturation from human peripheral blood mononuclear cells. Scand. J. Immunol. 1999; 50: 499-500.
32. Cella M., Jarrossay D., Facchetti F. et al. Plasmacytoid monocytes migrate to inflamed lymph nodes and produce large amounts of type I interferon. Nat. Med. 1999; 5: 919-923.
33. Mohty M., Jarrossay D., Latfage-Pochitaloff M. et al. Circulating blood dendritic cells from myeloid leukemia patients display quantitative and cytogenetic abnormalities as well as functional impairment. Blood 2001; 98 (13): 3750-3756.
34. Rostaing L., Tkaczuk J., Durand M. et al. Kinetics of intracytoplasmic Th1 and Th2 cytokine production assessed by flow cytometry following in vitro activation of PB mononuclear cells. Cytometry 1999; 35: 318-328.