Novel snake venom ligand dendroaspis natriuretic peptide is selective for natriuretic peptide receptor-A in human heart: Downregulation of natriuretic peptide receptor-A in heart failure

Circulation Research

Volumn 99, Issue 2, 2006, Pages 183-190

  Singh, Gurminder ^a   Kuc, Rhoda E ^a   Maguire, Janet J ^a   Fidock, Mark ^b   Davenport, Anthony P ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b PFIZER GLOBAL RESEARCH AND DEVELOPMENT   (United Kingdom)

Author keywords

Dendroaspis natriuretic peptide; Downregulation; Heart failure; Natriuretic peptide receptor A

Indexed keywords

ATRIAL NATRIURETIC FACTOR; BRAIN NATRIURETIC PEPTIDE; IODINE 125; NATRIURETIC FACTOR; NATRIURETIC PEPTIDE TYPE C; SNAKE VENOM; ATRIAL NATRIURETIC FACTOR RECEPTOR; ATRIAL NATRIURETIC FACTOR RECEPTOR A; DENDROASPIS NATRIURETIC PEPTIDE; GUANYLATE CYCLASE; LIGAND; MESSENGER RNA; PEPTIDE; RADIOACTIVE IODINE;

ADULT; ARTERY MUSCLE; ARTICLE; BINDING AFFINITY; BINDING SITE; CLINICAL ARTICLE; CONGESTIVE CARDIOMYOPATHY; CONTROLLED STUDY; CORONARY ARTERY; DOWN REGULATION; ENDOCARDIUM; ENDOTHELIUM CELL; ENZYME DEGRADATION; FEMALE; FLUORESCENCE; HEART FAILURE; HEART LEFT VENTRICLE; HEART MUSCLE CELL; HUMAN; HUMAN TISSUE; IMMUNOCYTOCHEMISTRY; ISCHEMIC HEART DISEASE; MALE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FAMILY; RECEPTOR BINDING; SMOOTH MUSCLE; STATISTICAL SIGNIFICANCE; CHEMISTRY; CONGESTIVE HEART FAILURE; CORONARY BLOOD VESSEL; GENETICS; HEART MUSCLE; HEART VENTRICLE; IMMUNOHISTOCHEMISTRY; METABOLISM; MIDDLE AGED; PROTEIN BINDING;

ADULT; BINDING SITES; CORONARY VESSELS; DOWN-REGULATION; ELAPID VENOMS; FEMALE; GUANYLATE CYCLASE; HEART FAILURE, CONGESTIVE; HEART VENTRICLES; HUMANS; IMMUNOHISTOCHEMISTRY; IODINE RADIOISOTOPES; LIGANDS; MALE; MIDDLE AGED; MYOCARDIUM; PEPTIDES; PROTEIN BINDING; RECEPTORS, ATRIAL NATRIURETIC FACTOR; RNA, MESSENGER; SNAKE VENOMS;

EID: 33747605830     PISSN: 00097330     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.RES.0000232322.06633.d3     Document Type: Article

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