Synthesis and duplex-forming property of oligonucleotides bearing a novel polyamine-modified intercalator at the terminal or the internal position

Nucleosides, Nucleotides and Nucleic Acids

Volumn 25, Issue 4-6, 2006, Pages 601-612

  Moriguchi, Tomohisa ^a   Sekiguchi, Hirokazu ^a   Tachibana, Makoto ^a   Shinozuka, Kazuo ^a  

^a GUNMA UNIVERSITY   (Japan)

Author keywords

Anthraquinone; Antisense DNA; Intercalator

Indexed keywords

ANTHRAQUINONE; COMPLEMENTARY DNA; INTERCALATING AGENT; OLIGONUCLEOTIDE; POLYAMINE;

ARTICLE; CHEMICAL STRUCTURE; CONJUGATION; MOLECULAR STABILITY; NUCLEOTIDE METABOLISM; POLYAMINE METABOLISM; STRUCTURE ACTIVITY RELATION; SURFACE CHARGE;

BASE SEQUENCE; INTERCALATING AGENTS; MOLECULAR SEQUENCE DATA; MOLECULAR STRUCTURE; NUCLEIC ACID DENATURATION; OLIGONUCLEOTIDES; POLYAMINES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 33747597260     PISSN: 15257770     EISSN: 15322335     Source Type: Journal    
DOI: 10.1080/15257770600685982     Document Type: Article

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18. Yields and ESI-mass data of modified oligonucleotides. ODN-1: 21.8%, calcd. 4895.3, found 4894.9; ODN-2: 11.9%, calcd. 4859.3, found 4859.3; ODN-3: 8.5%, calcd. 5039.5, found 5039.1; ODN-4: calcd. 5003.5, found 5003.0.