Supportive care after brain death for the donor candidate

International Anesthesiology Clinics

Volumn 44, Issue 3, 2006, Pages 21-34

  Hevesi, Zoltan G ^a   Lopukhin, Sergei Y ^a   Angelini, Giuditta ^a   Coursin, Douglas B ^a  

^a UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BRAIN DEATH; HEART; HUMAN; INTESTINE; KIDNEY; LIVER; LUNG; ORGAN TRANSPLANTATION; PANCREAS; PATIENT CARE; PRIORITY JOURNAL; REVIEW; DONOR; ORGAN PRESERVATION; PEROPERATIVE CARE; REPERFUSION INJURY; TRANSPLANTATION;

BRAIN DEATH; HUMANS; INTRAOPERATIVE CARE; ORGAN PRESERVATION; REPERFUSION INJURY; TISSUE AND ORGAN PROCUREMENT; TISSUE DONORS;

EID: 33747518666     PISSN: 00205907     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.aia.0000210798.53007.4b     Document Type: Review

References (71)

1. Sheehy E, Conrad SL, Brigham LE, et al. Estimating the number of potential organ donors in the United States. N Engl J Med. 2003;349:667-674.
2. Younger SJ, Landefeld CS, Coulton CJ, et al. 'Brain death' and organ retrieval: a cross-sectional survey of knowledge and concepts among health care professionals. JAMA. 1989;261:2205-2210.
3. Federal Condition of Participation of the Centers for Medicare and Medicaid Services: Organ, tissue, and eye procurement. (42 CFR 482.45).
4. Wood KE, Becker BN, McCartney JG, et al. Current concepts: care of the potential organ donor. N Engl J Med. 2004;351:2730-2739.
5. Angelis M, Cooper JT, Freeman RB. Impact of donor infections on outcome of orthotopic liver transplantation. Liver Transplant. 2003;9:451-462.
6. Freeman RB, Giatras I, Falagas ME, et al. Outcome of transplantation of organs procured from bacteremic donors. Transplantation. 1999;68:1107-1111.
7. The Organ Donation Breakthrough Collaborative. Best practices final report, September 2003 (http://www.organdonor.gov/bestpractice.htm).
8. Gortmaker SL, Beasley CL, Sheehy E, et al. Improving the request process to increase family consent for organ donation. J Transpl Coord. 1998;8:210-217.
9. Williams MA, Lipsett PA, Rushton CH, et al. The physician's role in discussing organ donation with families. Crit Care Med. 2003;31:1568-1573.
10. Lopez-Navidad A, Domingo P, Viedma MA. Professional characteristics of the transplant coordinator. Transplant Proc. 1997;29:1607-1613.
11. Siminoff LA, Gordon N, Hewlwtt J, et al. Factors influencing families' consent for donation of solid organs for transplantation. JAMA. 2001;286:71-77.
12. Nygaard CE, Townsend RN, Diamond DL. Organ donor management and organ outcome: a 6-year review from a level I trauma center. J Trauma. 1990;30:728-732.
13. Grossman MD, Reilly PM, McMahon DJ, et al. Loss of potential organ donors due to medical failure. Crit Care Med. 1996;24:A76.
14. Ad Hoc Committee of the Harvard Medical School to examine the definition of brain death. A definition of irreversible coma. JAMA. 1968;205:337-340.
15. Presidential Commission for the Study of Ethical Problems in Medicine and Biomedical and Behavioral Research. Guidelines for the determination of death. JAMA. 1981;246:2184-2186.
16. Wijdicks EFM. Determining brain death in adults. Neurology. 1995;45:1003-1011.
17. Wijdicks EF. The diagnosis of brain death. N Engl J Med. 2001;344:1215-1221.
18. Wijdicks EF. Brain death worldwide: accepted fact but no global consensus in diagnostic criteria. Neurology. 2002;58:20-25.
19. Wilhelm MJ, Pratschke J, Laskowski IA, et al. Brain death and its impact on the donor heart - lessons from animal models. J Heart Lung Transplant. 2000;19:414-418.
20. Baroldi G, Di Pasquale G, Silver MD, et al. Type and extent of myocardial injury related to brain damage and its significance in heart transplantation: a morphometric study. J Heart Lung Transplant. 1997;16:994-1000.
21. Novitzky D, Horak A, Cooper DK, et al. Electrocardiographic and histopathologic changes developing during experimental brain death in the baboon. Transplant Proc. 1989;21:2567-2569.
22. Kolin A, Norris JW. Myocardial damage from acute cerebral lesions. Stroke. 1984;15:990-993.
23. Shivalkar B, Van Loon J, Wieland W, et al. Variable effects of explosive or gradual increase of intracranial pressure on myocardial structure and function. Circulation. 1993;87:230-239.
24. Terasaki PI, Cecka JM, Gjertson DW, et al. High survival rates of kidney transplants from spousal and living unrelated donors. NEJM. 1995;333:333-336.
25. Wheeldon DR, Potter CD, Oduro A, et al. Transforming the "unacceptable" donor: outcomes from the adoption of a standardized donor management technique. J Heart Lung Transplant. 1995;14:734-742.
26. Rosendale JD, Chabalewski FL, McBride MA, et al. Increased transplanted organs from the use of a standardized donor management protocol. Am J Transplant. 2002;2:761-768.
27. Rosendale JD, Kauffman HM, McBride MA, et al. Aggressive pharmacologic donor management results in more transplanted organs. Transplantation. 2003;75:482-487.
28. Power BM, Van Heerden PV. The physiological changes associated with brain death-current concepts and implications for treatment of the brain dead organ donor. Anaesth Intensive Care. 1995;23:26-36.
29. Whelchel JD, Diethelm AG, Phillips MD, et al. The effect of high dose dopamine in cadaveric donor management on delayed graft function and graft survival following renal transplantation. Transplant Proc. 1986;18:523-527.
30. Reilly PM, Grossman MD, Rosengard BR, et al. Lung procurement from solid organ donors: role of fluid resuscitation in procurement failures. Chest. 1996;110:222S.
31. Pennefather SH, Bullock RE, Dark JH. The effect of fluid therapy on alveolar arterial oxygen gradient in brain-dead organ donors. Transplantation. 1993;56:1418-1422.
32. Cittanova ML, Leblanc I, Legendre C, et al. Effect of hydroxyethylstarch in brain-dead kidney donors on renal function in kidney-transplant recipients. Lancet. 1996;348:1620-1622.
33. Schnuelle P, Lorenz D, Mueller A, et al. Donor catecholamine use reduces acute allograft rejection and improves graft survival after cadaveric renal transplantation. Kidney Int. 1999;56:738-746.
34. Schnuelle P, Berger S, de Boer J, et al. Effects of catecholamine application to brain-dead donors on graft survival in solid organ transplantation. Transplantation. 2001;72:455-463.
35. Ueno T, Zhi-Li C, Itoh T. Unique circulatory responses to exogenous catecholamines after brain death. Transplantation. 2000;70:436-440.
36. Tilney NL, Paz D, Ames J, et al. Ischemia-reperfusion injury. Transplant Proc. 2001;33:843-844.
37. Amado JA, Lopez-Espadas F, Vazquez-Barquero A, et al. Blood levels of cytokines in brain-dead patients: relationship with circulating hormones and acute-phase reactants. Metabolism. 1995;44:812-816.
38. Stangl M, Zerkaulen T, Theodorakis J, et al. Influence of brain death on cytokine release in organ donors and renal transplants. Transplant Proc. 2001;33:1284-1285.
39. Richardson DW, Robinson AG. Desmopressin. Ann Intern Med. 1985;103:228-239.
40. Howlett TA, Keogh AM, Perry L, et al. Anterior and posterior pituitary function in brain-stem-dead donors: a possible role for hormonal replacement therapy. Transplantation. 1989;47:828-834.
41. Gramm HJ, Meinhold H, Bickel U, et al. Acute endocrine failure after brain death? Transplantation. 1992;54:851-857.
42. Novitzky D, Wicomb WN, Rose AG, et al. Pathophysiology of pulmonary edema following experimental brain death in the chacma baboon. Ann Thorac Surg. 1987;43:288-294.
43. Follette DM, Rudich SM, Babcock WD. Improved oxygenation and increased lung donor recovery with high-dose steroid administration after brain death. J Heart Lung Transplant. 1998;17:423-429.
44. Sakuma T, Folkesson HG, Suzuki S, et al. Betaadrenergic agonist stimulated alveolar fluid clearance in ex vivo human and rat lungs. Am J Respir Crit Care Med. 1997;155:506-512.
45. Gabbay E, Williams TJ, Griffiths AP, et al. Maximizing the utilization of donor organs offered for lung transplantation. Am J Respir Crit Care Med. 1999;160:265-271.
46. Follette D, Rudich S, Bonacci C, et al. Importance of an aggressive multidisciplinary management approach to optimize lung donor procurement. Transplant Proc. 1999;31:169-170.
47. Parry A, Higgins R, Wheeldon D, et al. The contribution of donor management and modified cold blood lung perfusate to post-transplant lung function. J Heart Lung Transplant. 1999;18:121-126.
48. Cummings J, Houck J, Lichtenfeld D. Positive effect of aggressive resuscitative efforts on cadaver lung procurement. J Transplant Coordination. 1995;5:103-106.
49. Masson F, Thicoipe M, Gin H, et al. The endocrine pancreas in brain-dead donors. Transplantation. 1993;56:363-367.
50. Hefty TR, Cotterell LW, Fraser SC, et al. Disseminated intravascular coagulation in cadaveric organ donors: incidence and effect on renal transplantation. Transplantation. 1993;55:442-443.
51. Powner DJ, Hendrich A, Lagler RG, et al. Hormonal changes in brain dead patients. Crit Care Med. 1990;18:702-708.
52. Pennefather SH, Bullock RE, Mantle D, et al. Use of low dose arginine vasopressin to support brain-dead organ donors. Transplantation. 1995;59:58-62.
53. Yoshioka T, Sugimoto H, Uenishi M, et al. Prolonged hemodynamic maintenance by the combined administration of vasopressin and epinephrine in brain death: a clinical study. Neurosurgery. 1986;18:565-567.
54. Marik PE, Zaloga GP. Adrenal insufficiency in the critically ill: a new look at an old problem. Chest. 2002;122:1784-1796.
55. Novitzky D. Donor management: state of the art. Transplant Proc. 1997;29:3773-3775.
56. Rosendale JD, Kauffman HM, McBride MA, et al. Aggressive pharmacologic donor management results in more transplanted organs. Transplantation. 2003;75:482-487.
57. Novitzky D, Cooper DK, Reichart B. Hemodynamic and metabolic responses to hormonal therapy in brain-dead potential organ donors. Transplantation. 1987;43:852-854.
58. Novitzky D, Cooper DK, Morrell D, et al. Change from aerobic to anaerobic metabolism after brain death, and reversal following triiodothyronine therapy. Transplantation. 1988;45:32-36.
59. Salim A, Vassiliu P, Velmahos GC, et al. The role of thyroid hormone administration in potential organ donors. Arch Surg. 2001;136:1377-1380.
60. Rosendale JD, Kauffman HM, McBride MA, et al. Hormonal resuscitation yields more transplanted hearts, with improved early function. Transplantation. 2003;75:1336-1341.
61. Zaroff JG, Rosengard BR, Armstrong WF, et al. Consensus conference report: maximizing use of organs recovered from the cadaver donor. Circulation. 2002;106:836-841.
62. Randell TT, Hockerstedt KA. Triiodothyronine treatment in brain-dead multiorgan donors-a controlled study. Transplantation. 1992;54:736-738.
63. Goarin JP, Cohen S, Riou B, et al. The effects of triiodothyronine on hemodynamic status and cardiac function in potential heart donors. Anesth Analg. 1996;83:41-47.
64. Southard JH, van Gulik TM, Ametani MS, et al. Important components of the UW solution. Transplantation. 1990;49:251-257.
65. Stringham JC, Southard JH, Anderson GM, et al. Mechanisms of ATP depletion in the cold-stored heart. Transplant Proc. 1991;23:2437-2438.
66. Wahlberg JA, Southard JH, Belzer FO. Development of a cold storage solution for pancreas preservation. Cryobiology. 1986;23:477-482.
67. D'Alessandro AM, Kalayoglu M, Sollinger HW, et al. Current status of organ preservation with University of Wisconsin solution. Arch Pathol Lab Med. 1991;115:306-310.
68. Southard JH. Improving early graft function: role of preservation. Transplant Proc. 1997;29:3510-3511.
69. Lopukhin SY, Onsager DR, Conhaim RL, et al. University of Wisconsin solution with butanedione monoxime and calcium improves rat lung preservation. Ann Thorac Surg. 1999;67:203-207.
70. Jenkins DH, Reilly PM, Schwab CW. Improving the approach to organ donation: a review. World J Surg. 1999;23:644-649.
71. Lopez-Navidad A, Caballero F. For a rational approach to the critical points of the cadaveric donation process. Transplant Proc. 2001;33:795-805.