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Volumn 49, Issue 17, 2006, Pages 5047-5050

Low molecular weight activated protein C inhibitors as a potential treatment for hemophilic disorders

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATED PROTEIN C; ACTIVATED PROTEIN C INHIBITOR; ANTICOAGULANT AGENT; BENZAMIDINE DERIVATIVE; BLOOD CLOTTING FACTOR 8A; PROCOAGULANT; PROTEINASE INHIBITOR; SERINE PROTEINASE; UNCLASSIFIED DRUG;

EID: 33747501427     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm0606950     Document Type: Article
Times cited : (22)

References (10)
  • 2
    • 4344674120 scopus 로고    scopus 로고
    • Recombinant biologies for treatment of bleeding disorders
    • Bishop, P.; Lawson, J. Recombinant Biologies for Treatment of Bleeding Disorders. Nat. Rev. Drug Discovery 2004, 3, 684-694.
    • (2004) Nat. Rev. Drug Discovery , vol.3 , pp. 684-694
    • Bishop, P.1    Lawson, J.2
  • 3
    • 0031710556 scopus 로고    scopus 로고
    • The anticoagulant potential of the protein C system in hereditary and acquired thrombophilia: Pathomechanisms and new tools for assessing its clinical relevance
    • Kraus, M. The Anticoagulant Potential of the Protein C System in Hereditary and Acquired Thrombophilia: Pathomechanisms and New Tools for Assessing Its Clinical Relevance. Semin. Thromb. Hemostasis 1998, 24, 337-354.
    • (1998) Semin. Thromb. Hemostasis , vol.24 , pp. 337-354
    • Kraus, M.1
  • 4
    • 33747457120 scopus 로고    scopus 로고
    • Peptidomimetics Containing 6-Peptidylamino-1-Naphthalenesulfonamide Moieties. World Patent WO 98/22125, 1998
    • Butenas, S.; Mann, K. Peptidomimetics Containing 6-Peptidylamino-1- Naphthalenesulfonamide Moieties. World Patent WO 98/22125, 1998.
    • Butenas, S.1    Mann, K.2
  • 5
    • 33747492134 scopus 로고    scopus 로고
    • note
    • 50 value with that obtained against thrombin in the presence of its natural substrate, fibrinogen (Enzyme Research Laboratories).
  • 6
    • 0031794772 scopus 로고    scopus 로고
    • Large scale preparation of protected 4-aminomethylbenzamidine. Application to the synthesis of the thrombin inhibitor melagatran
    • Lila, C.; Gloanec, P.; Cadet, L.; Hervé, Y.; Fournier, J.; Leborgne, F.; Verbeuren, T. J.; De Nanteuil, G. Large Scale Preparation of Protected 4-Aminomethylbenzamidine. Application to the Synthesis of the Thrombin Inhibitor Melagatran. Synth. Commun. 1998, 28, 4419-4429.
    • (1998) Synth. Commun. , vol.28 , pp. 4419-4429
    • Lila, C.1    Gloanec, P.2    Cadet, L.3    Hervé, Y.4    Fournier, J.5    Leborgne, F.6    Verbeuren, T.J.7    De Nanteuil, G.8
  • 10
    • 0037171819 scopus 로고    scopus 로고
    • Structure-based design of novel potent nonpeptide thrombin inhibitors
    • Hauel, N. H.; Nar, H.; Priepke, H.; Ries, U.; Stassen, J.-M.; Wienen, W. Structure-Based Design of Novel Potent Nonpeptide Thrombin Inhibitors. J. Med. Chem. 2002, 45, 1757-1766.
    • (2002) J. Med. Chem. , vol.45 , pp. 1757-1766
    • Hauel, N.H.1    Nar, H.2    Priepke, H.3    Ries, U.4    Stassen, J.-M.5    Wienen, W.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.