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Volumn 18, Issue 4, 2006, Pages 417-422

Cutaneous manifestations of nutritional deficiency

Author keywords

Acrodermatitis enteropathica; B12; Biotin; Kwashiorkor; Niacin; Pellagra; Phrynoderma; Selenium

Indexed keywords

BIOTIN; CYANOCOBALAMIN; NICOTINIC ACID; PROTEIN; RETINOL; SELENIUM; TRACE ELEMENT; VITAMIN; ZINC;

EID: 33747495901     PISSN: 10408703     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.mop.0000236392.87203.cc     Document Type: Review
Times cited : (55)

References (44)
  • 1
    • 3042823706 scopus 로고    scopus 로고
    • Severe vitamin B12 deficiency in an infant associated with a maternal deficiency and a strict vegetarian diet
    • Weiss R, Fogelman Y, Bennett M. Severe vitamin B12 deficiency in an infant associated with a maternal deficiency and a strict vegetarian diet. J Pediatr Hematol Oncol 2004; 26:270-271.
    • (2004) J Pediatr Hematol Oncol , vol.26 , pp. 270-271
    • Weiss, R.1    Fogelman, Y.2    Bennett, M.3
  • 2
    • 0034746436 scopus 로고    scopus 로고
    • Vitamin B12 deficiency in children and adolescents
    • Rasmussen SA, Fernhoff PM, Scanlon KS. Vitamin B12 deficiency in children and adolescents. J Pediatr 2001; 138:10-17.
    • (2001) J Pediatr , vol.138 , pp. 10-17
    • Rasmussen, S.A.1    Fernhoff, P.M.2    Scanlon, K.S.3
  • 3
    • 10944245290 scopus 로고    scopus 로고
    • A child with vitamin B12 deficiency presenting with pancytopenia and hyperpigmentation
    • Simsek OP, Gonc N, Gumruk F, Cetin M. A child with vitamin B12 deficiency presenting with pancytopenia and hyperpigmentation. J Pediatr Hematol Oncol 2004; 26:834-836.
    • (2004) J Pediatr Hematol Oncol , vol.26 , pp. 834-836
    • Simsek, O.P.1    Gonc, N.2    Gumruk, F.3    Cetin, M.4
  • 5
    • 0028631135 scopus 로고
    • Imerslund-Grasbeck syndrome in a Chinese family with distinct skin lesions refractory to vitamin B12
    • Lin SH, Sourial NA, Lu KC, Hsueh EJ. Imerslund-Grasbeck syndrome in a Chinese family with distinct skin lesions refractory to vitamin B12. J Clin Pathol 1994; 47:956-958.
    • (1994) J Clin Pathol , vol.47 , pp. 956-958
    • Lin, S.H.1    Sourial, N.A.2    Lu, K.C.3    Hsueh, E.J.4
  • 6
    • 0034973519 scopus 로고    scopus 로고
    • Generalized hyperpigmentation of the skin due to vitamin B12 deficiency
    • Mori K, Ando I, Kukita A. Generalized hyperpigmentation of the skin due to vitamin B12 deficiency. J Dermatol 2001; 28:282-285.
    • (2001) J Dermatol , vol.28 , pp. 282-285
    • Mori, K.1    Ando, I.2    Kukita, A.3
  • 7
    • 0015582169 scopus 로고
    • Epidermal changes in vitamin B12 deficiency
    • Gilliam J, Cox J. Epidermal changes in vitamin B12 deficiency. Arch Dermatol 1973; 107:231-236.
    • (1973) Arch Dermatol , vol.107 , pp. 231-236
    • Gilliam, J.1    Cox, J.2
  • 8
    • 0031705372 scopus 로고    scopus 로고
    • Cobalamin deficiency presenting with cutaneous hyperpigmentation: A report of two siblings
    • Sabatino D, Kosuri S, Remollino A, Shotter B. Cobalamin deficiency presenting with cutaneous hyperpigmentation: a report of two siblings. Pediatr Hematol Oncol 1998; 15:447-450.
    • (1998) Pediatr Hematol Oncol , vol.15 , pp. 447-450
    • Sabatino, D.1    Kosuri, S.2    Remollino, A.3    Shotter, B.4
  • 9
    • 0344406128 scopus 로고    scopus 로고
    • Clinical manifestations of the mouth revealing Vitamin B12 deficiency before the onset of anemia
    • Petavy-Catala C, Fontes V, Gironet N, et al. Clinical manifestations of the mouth revealing Vitamin B12 deficiency before the onset of anemia. Ann Dermatol Venereol 2003; 130:191-194.
    • (2003) Ann Dermatol Venereol , vol.130 , pp. 191-194
    • Petavy-Catala, C.1    Fontes, V.2    Gironet, N.3
  • 10
    • 9944229502 scopus 로고    scopus 로고
    • Initial diagnosis of anemia from sore mouth and improved classification of anemias by MCV and RDW in 30 patients
    • Lu SY, Wu HC. Initial diagnosis of anemia from sore mouth and improved classification of anemias by MCV and RDW in 30 patients. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2004; 98:679-685.
    • (2004) Oral Surg Oral Med Oral Pathol Oral Radiol Endod , vol.98 , pp. 679-685
    • Lu, S.Y.1    Wu, H.C.2
  • 11
    • 0035319213 scopus 로고    scopus 로고
    • Severe nutritional deficiencies in toddlers resulting from health food milk alternatives
    • Carvalho NF, Kenney RD, Carrington PH, Hall DE. Severe nutritional deficiencies in toddlers resulting from health food milk alternatives. Pediatrics 2001; 107:E46.
    • (2001) Pediatrics , vol.107
    • Carvalho, N.F.1    Kenney, R.D.2    Carrington, P.H.3    Hall, D.E.4
  • 12
    • 4143108926 scopus 로고    scopus 로고
    • A toddler with developmental regression
    • Phila
    • Tosh A, Fischer PR. A toddler with developmental regression. Clin Pediatr (Phila) 2004; 43:305-306.
    • (2004) Clin Pediatr , vol.43 , pp. 305-306
    • Tosh, A.1    Fischer, P.R.2
  • 13
    • 2442691823 scopus 로고    scopus 로고
    • Skin signs as the presenting manifestation of severe nutritional deficiency: Report of 2 cases
    • Kuhl J, Davis MD, Kalaaji AN, et al. Skin signs as the presenting manifestation of severe nutritional deficiency: report of 2 cases. Arch Dermatol 2004; 140:521-524.
    • (2004) Arch Dermatol , vol.140 , pp. 521-524
    • Kuhl, J.1    Davis, M.D.2    Kalaaji, A.N.3
  • 14
    • 0035922817 scopus 로고    scopus 로고
    • Kwashiorkor after an exclusion diet for eczema
    • Nguyen J, Cazassus F, Atallah A, et al. Kwashiorkor after an exclusion diet for eczema. Presse Med 2001; 30:1496-1497.
    • (2001) Presse Med , vol.30 , pp. 1496-1497
    • Nguyen, J.1    Cazassus, F.2    Atallah, A.3
  • 15
  • 16
    • 33644876598 scopus 로고    scopus 로고
    • Rice nightmare: Kwashiorkor in 2 Philadelphia-area infants fed Rice Dream beverage
    • Katz KA, Mahlberg MH, Honig PJ, Yan AC. Rice nightmare: Kwashiorkor in 2 Philadelphia-area infants fed Rice Dream beverage. J Am Acad Dermatol 2005; 52:S69-S72. This report discusses the presentation of two children whose primary caloric intake was a rice-based beverage mistakenly believed to provide adequate nutritional support. Both children presented with classic findings of kwashiorkor. Both additionally had hypozincemia. The authors also review the literature of kwashiorkor reports in developed nations.
    • (2005) J Am Acad Dermatol , vol.52
    • Katz, K.A.1    Mahlberg, M.H.2    Honig, P.J.3    Yan, A.C.4
  • 17
    • 0035018329 scopus 로고    scopus 로고
    • Kwashiorkor in the United States: Fad diets, perceived and true milk allergy, and nutritional ignorance
    • Liu T, Howard RM, Mancini AJ, et al. Kwashiorkor in the United States: fad diets, perceived and true milk allergy, and nutritional ignorance. Arch Dermatol 2001; 137:630-636.
    • (2001) Arch Dermatol , vol.137 , pp. 630-636
    • Liu, T.1    Howard, R.M.2    Mancini, A.J.3
  • 18
    • 4644272702 scopus 로고    scopus 로고
    • Sweat test results in children with primary protein energy malnutrition
    • Yigit H, Selimoglu MA, Altinkaynak S. Sweat test results in children with primary protein energy malnutrition. J Pediatr Gastroenterol Nutr 2003; 37:242-245.
    • (2003) J Pediatr Gastroenterol Nutr , vol.37 , pp. 242-245
    • Yigit, H.1    Selimoglu, M.A.2    Altinkaynak, S.3
  • 19
    • 0036087879 scopus 로고    scopus 로고
    • Biotin dependency due to a defect in biotin transport
    • Mardach R, Zempleni J, Wolf B, et al. Biotin dependency due to a defect in biotin transport. J Clin Invest 2002; 109:1617-1623.
    • (2002) J Clin Invest , vol.109 , pp. 1617-1623
    • Mardach, R.1    Zempleni, J.2    Wolf, B.3
  • 20
    • 0020525812 scopus 로고
    • Biotinidase deficiency: The enzymatic defect in late-onset multiple carboxylase deficiency
    • Wolf B, Grier R, Allen R, et al. Biotinidase deficiency: the enzymatic defect in late-onset multiple carboxylase deficiency. Clin Chim Acta 1983; 131:273-281.
    • (1983) Clin Chim Acta , vol.131 , pp. 273-281
    • Wolf, B.1    Grier, R.2    Allen, R.3
  • 21
    • 19444362078 scopus 로고    scopus 로고
    • Hyperchylomicronaemia due to lipoprotein lipase deficiency as a cause of false-positive newborn screening for biotinidase deficiency
    • Santer R, Gokcay G, Demirkol M, et al. Hyperchylomicronaemia due to lipoprotein lipase deficiency as a cause of false-positive newborn screening for biotinidase deficiency. J Inherit Metab Dis 2005; 28:137-140.
    • (2005) J Inherit Metab Dis , vol.28 , pp. 137-140
    • Santer, R.1    Gokcay, G.2    Demirkol, M.3
  • 22
    • 0037405424 scopus 로고    scopus 로고
    • The effect of neonatal jaundice on biotinidase activity
    • Schulpis KH, Gavrili S, Tjamouranis J, et al. The effect of neonatal jaundice on biotinidase activity. Early Hum Dev 2003; 72:15-24.
    • (2003) Early Hum Dev , vol.72 , pp. 15-24
    • Schulpis, K.H.1    Gavrili, S.2    Tjamouranis, J.3
  • 23
    • 18044365978 scopus 로고    scopus 로고
    • Biotinidase deficiency: The importance of adequate follow-up for an inconclusive newborn screening result
    • Hoffman TL, Simon EM, Ficicioglu C. Biotinidase deficiency: the importance of adequate follow-up for an inconclusive newborn screening result. Eur J Pediatr 2005; 164:298-301. This is a case report of an adverse outcome after an inconclusive biotinidase newborn screening test without appropriate follow-up. It serves as a reminder of the importance of further laboratory confirmation and clinical follow-up in indeterminate initial screening tests.
    • (2005) Eur J Pediatr , vol.164 , pp. 298-301
    • Hoffman, T.L.1    Simon, E.M.2    Ficicioglu, C.3
  • 24
    • 3042730976 scopus 로고    scopus 로고
    • Outcome in patients with profound biotinidase deficiency: Relevance of newborn screening
    • Weber P, Scholl S, Baumgartner ER. Outcome in patients with profound biotinidase deficiency: relevance of newborn screening. Dev Med Child Neurol 2004; 46:481-484.
    • (2004) Dev Med Child Neurol , vol.46 , pp. 481-484
    • Weber, P.1    Scholl, S.2    Baumgartner, E.R.3
  • 25
    • 31644438877 scopus 로고    scopus 로고
    • Asymptomatic adults and older siblings with biotinidase deficiency ascertained by family studies of index cases
    • Baykal T, Gokcay G, Gokdemir Y, et al. Asymptomatic adults and older siblings with biotinidase deficiency ascertained by family studies of index cases. J Inherit Metab Dis 2005; 28:903-912. Family studies of biotinidase-deficient individuals revealed 32 deficient family members of the 121 individuals who were screened in this study. The authors describe wide phenotypic variation in the previously undiagnosed family members, including individuals with profound deficiency who did not have clinical manifestations. This paper also suggests that we should be screening asymptomatic family members especially the siblings of the index cases.
    • (2005) J Inherit Metab Dis , vol.28 , pp. 903-912
    • Baykal, T.1    Gokcay, G.2    Gokdemir, Y.3
  • 27
    • 19744375231 scopus 로고    scopus 로고
    • Biotin deficiency in an infant fed with amino acid formula
    • Fujimoto W, Inaoki M, Fukui T, et al. Biotin deficiency in an infant fed with amino acid formula. J Dermatol 2005; 32:256-261.
    • (2005) J Dermatol , vol.32 , pp. 256-261
    • Fujimoto, W.1    Inaoki, M.2    Fukui, T.3
  • 28
    • 0346888508 scopus 로고    scopus 로고
    • Normalization of low biotinidase activity in a child with biotin deficiency after biotin supplementation
    • Kimura M, Fukui T, Tagami Y, et al. Normalization of low biotinidase activity in a child with biotin deficiency after biotin supplementation. J Inherit Metab Dis 2003; 26:715-719.
    • (2003) J Inherit Metab Dis , vol.26 , pp. 715-719
    • Kimura, M.1    Fukui, T.2    Tagami, Y.3
  • 29
    • 21344436397 scopus 로고    scopus 로고
    • Biotin-dependent regulation of gene expression in human cells
    • Leon-Del-Rio A. Biotin-dependent regulation of gene expression in human cells. J Nutr Biochem 2005; 16:432-434.
    • (2005) J Nutr Biochem , vol.16 , pp. 432-434
    • Leon-Del-Rio, A.1
  • 30
    • 0037021546 scopus 로고    scopus 로고
    • Acrodermatitis enteropathica associated with anorexia nervosa
    • Quirk CM, Seykora J, Wingate BJ, Cotsarelis G. Acrodermatitis enteropathica associated with anorexia nervosa. JAMA 2002; 288:2655-2656.
    • (2002) JAMA , vol.288 , pp. 2655-2656
    • Quirk, C.M.1    Seykora, J.2    Wingate, B.J.3    Cotsarelis, G.4
  • 31
    • 22144431534 scopus 로고    scopus 로고
    • Acquired acrodermatitis enteropathica caused by anorexia nervosa
    • Tran KT, Kress D, Lamb PM. Acquired acrodermatitis enteropathica caused by anorexia nervosa. J Am Acad Dermatol 2005; 53:361-362.
    • (2005) J Am Acad Dermatol , vol.53 , pp. 361-362
    • Tran, K.T.1    Kress, D.2    Lamb, P.M.3
  • 32
    • 1242316306 scopus 로고    scopus 로고
    • Edema, anemia, hypoproteinemia, and acrodermatitis enteropathica: An uncommon initial presentation of cystic fibrosis
    • Muniz AE, Bartle S, Foster R. Edema, anemia, hypoproteinemia, and acrodermatitis enteropathica: an uncommon initial presentation of cystic fibrosis. Pediatr Emerg Care 2004; 20:112-114.
    • (2004) Pediatr Emerg Care , vol.20 , pp. 112-114
    • Muniz, A.E.1    Bartle, S.2    Foster, R.3
  • 34
    • 19644396418 scopus 로고    scopus 로고
    • An infant with acrodermatitis enteropathica-like symptoms but without hypozincemia
    • Chen MD, Song YM. An infant with acrodermatitis enteropathica-like symptoms but without hypozincemia. Pediatr Dermatol 2005; 22:280-281.
    • (2005) Pediatr Dermatol , vol.22 , pp. 280-281
    • Chen, M.D.1    Song, Y.M.2
  • 35
    • 0024442471 scopus 로고
    • Acrodermatitis enteropathica with normal serum zinc levels: Diagnostic value of small bowel biopsy and essential fatty acid determination
    • Mack D, Koletzko B, Cunnane S, et al. Acrodermatitis enteropathica with normal serum zinc levels: diagnostic value of small bowel biopsy and essential fatty acid determination. Gut 1989; 30:1426-1429.
    • (1989) Gut , vol.30 , pp. 1426-1429
    • Mack, D.1    Koletzko, B.2    Cunnane, S.3
  • 36
    • 20644466425 scopus 로고    scopus 로고
    • Selenium deficiency: Report of a case
    • Kanekura T, Yotsumoto S, Maeno N, et al. Selenium deficiency: report of a case. Clin Exp Dermatol 2005; 30:346-348. While this is a single case report, it deserves mention as this is the first description of significant cutaneous findings attributable to selenium deficiency. Response to selenium replacement supports that this deficiency was the etiologic factor of the cutaneous findings in this child.
    • (2005) Clin Exp Dermatol , vol.30 , pp. 346-348
    • Kanekura, T.1    Yotsumoto, S.2    Maeno, N.3
  • 37
    • 13244281883 scopus 로고    scopus 로고
    • Temporal relationship between the occurrence of fresh noma and the timing of linear growth retardation in Nigerian children
    • Enwonwu CO, Phillips RS, Ferrell CD. Temporal relationship between the occurrence of fresh noma and the timing of linear growth retardation in Nigerian children. Trop Med Int Health 2005; 10:65-73.
    • (2005) Trop Med Int Health , vol.10 , pp. 65-73
    • Enwonwu, C.O.1    Phillips, R.S.2    Ferrell, C.D.3
  • 38
    • 12944271031 scopus 로고
    • Phrynoderma: A condition due to vitamin deficiency
    • Nicholls L. Phrynoderma: a condition due to vitamin deficiency. Indian Med Gazette 1933; 63:681-687.
    • (1933) Indian Med Gazette , vol.63 , pp. 681-687
    • Nicholls, L.1
  • 39
    • 12944260521 scopus 로고    scopus 로고
    • Phrynoderma: A manifestation of vitamin A deficiency? The rest of the story
    • Maronn M, Allen DM, Esterly NB. Phrynoderma: a manifestation of vitamin A deficiency? The rest of the story. Pediatr Dermatol 2005; 22:60-63. This is a case report with a good review of the literature. It highlights that phrynoderma is a clinical diagnosis without a specific underlying etiology. When discovered multiple nutritional deficiencies should be considered and investigated.
    • (2005) Pediatr Dermatol , vol.22 , pp. 60-63
    • Maronn, M.1    Allen, D.M.2    Esterly, N.B.3
  • 40
    • 0024217311 scopus 로고
    • Phrynoderma: A review of 105 cases
    • Nakjang Y, Yuttanavivat T. Phrynoderma: a review of 105 cases. J Dermatol 1988; 15:531-534.
    • (1988) J Dermatol , vol.15 , pp. 531-534
    • Nakjang, Y.1    Yuttanavivat, T.2
  • 41
    • 0842325192 scopus 로고    scopus 로고
    • Pellagra: Dermatitis, dementia, and diarrhea
    • Hegyi J, Schwartz RA, Hegyi V. Pellagra: dermatitis, dementia, and diarrhea. Int J Dermatol 2004; 43:1-5.
    • (2004) Int J Dermatol , vol.43 , pp. 1-5
    • Hegyi, J.1    Schwartz, R.A.2    Hegyi, V.3
  • 42
    • 27744550298 scopus 로고    scopus 로고
    • Biochemical assessment of niacin deficiency among carcinoid cancer patients
    • Shah GM, Shah RG, Veillette H, et al. Biochemical assessment of niacin deficiency among carcinoid cancer patients. Am J Gastroenterol 2005; 100:2307-2314.
    • (2005) Am J Gastroenterol , vol.100 , pp. 2307-2314
    • Shah, G.M.1    Shah, R.G.2    Veillette, H.3
  • 43
    • 20644472656 scopus 로고    scopus 로고
    • Nutritional deficiencies and the skin
    • MacDonald A, Forsyth A. Nutritional deficiencies and the skin. Clin Exp Dermatol 2005; 30:388-390. This is a case report of two individuals with dermatologic findings as their primary manifestation of nutritional deficiencies. One notably with anorexia resulting in pellagra, the other with atopic dermatitis and perceived and real food intolerances (presumed to flare the atopic dermatitis) resulting in significant self-imposed food restrictions. Multiple deficiencies were found in both patients, highlighting the overlap of deficiencies that can be seen and the need to screen for multiple concomitant deficiencies.
    • (2005) Clin Exp Dermatol , vol.30 , pp. 388-390
    • MacDonald, A.1    Forsyth, A.2
  • 44
    • 0038011831 scopus 로고    scopus 로고
    • Pellagra may be a rare secondary complication of anorexia nervosa: A systematic review of the literature
    • Prousky JE. Pellagra may be a rare secondary complication of anorexia nervosa: a systematic review of the literature. Altern Med Rev 2003; 8:180-185.
    • (2003) Altern Med Rev , vol.8 , pp. 180-185
    • Prousky, J.E.1


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