-
1
-
-
0037623521
-
The Rapamune era of immunosuppression 2003: The journey from the laboratory to clinical transplantation
-
Camardo J. The Rapamune era of immunosuppression 2003: the journey from the laboratory to clinical transplantation. Transplant Proc 2003; 35(3 Suppl): 18S.
-
(2003)
Transplant Proc
, vol.35
, Issue.3 SUPPL.
-
-
Camardo, J.1
-
2
-
-
0027371861
-
Rapamycin inhibition of interleukin-2-dependent p33cdk2 and p34cdc2 kinase activation in T lymphocytes
-
Morice WG, Wiederrecht G, Brunn GJ, et al. Rapamycin inhibition of interleukin-2-dependent p33cdk2 and p34cdc2 kinase activation in T lymphocytes. J Biol Chem 1993; 268(30): 22737.
-
(1993)
J Biol Chem
, vol.268
, Issue.30
, pp. 22737
-
-
Morice, W.G.1
Wiederrecht, G.2
Brunn, G.J.3
-
3
-
-
0037623419
-
Molecular actions of sirolimus: Sirolimus and mTor
-
Kirken RA, Wang YL. Molecular actions of sirolimus: sirolimus and mTor. Transplant Proc 2003; 35(3 Suppl): 227S.
-
(2003)
Transplant Proc
, vol.35
, Issue.3 SUPPL.
-
-
Kirken, R.A.1
Wang, Y.L.2
-
4
-
-
0346848743
-
Sirolimus delays recovery of rat kidney transplants after ischemia-reperfusion injury
-
Fuller TF, Freise CE, Serkova N, et al. Sirolimus delays recovery of rat kidney transplants after ischemia-reperfusion injury. Transplantation 2003; 76(11): 1594.
-
(2003)
Transplantation
, vol.76
, Issue.11
, pp. 1594
-
-
Fuller, T.F.1
Freise, C.E.2
Serkova, N.3
-
5
-
-
4043171462
-
Upstream and downstream of mTOR
-
Hay N, Sonenberg N. Upstream and downstream of mTOR. Genes Dev 2004; 18(16): 1926.
-
(2004)
Genes Dev
, vol.18
, Issue.16
, pp. 1926
-
-
Hay, N.1
Sonenberg, N.2
-
6
-
-
0031755688
-
Studies on the mechanism of resistance to rapamycin in human cancer cells
-
Hosoi H, Dilling MB, Liu LN, et al. Studies on the mechanism of resistance to rapamycin in human cancer cells. Mol Pharmacol 1998; 54(5): 815.
-
(1998)
Mol Pharmacol
, vol.54
, Issue.5
, pp. 815
-
-
Hosoi, H.1
Dilling, M.B.2
Liu, L.N.3
-
7
-
-
0034823939
-
Rapamycin-sensitive phase of 3T3-L1 preadipocyte differentiation after clonal expansion
-
Gagnon A, Lau S, Sorisky A. Rapamycin-sensitive phase of 3T3-L1 preadipocyte differentiation after clonal expansion. J Cell Physiol 2001; 189(1): 14.
-
(2001)
J Cell Physiol
, vol.189
, Issue.1
, pp. 14
-
-
Gagnon, A.1
Lau, S.2
Sorisky, A.3
-
8
-
-
0036275356
-
Hypoxia enhances vascular cell proliferation and angiogenesis in vitro via rapamycin (mTOR)-dependent signaling
-
Humar R, Kiefer FN, Berns H, et al. Hypoxia enhances vascular cell proliferation and angiogenesis in vitro via rapamycin (mTOR)-dependent signaling. Faseb J 2002; 16(8): 771.
-
(2002)
Faseb J
, vol.16
, Issue.8
, pp. 771
-
-
Humar, R.1
Kiefer, F.N.2
Berns, H.3
-
9
-
-
0032738763
-
Rapamycin inhibits hepatic stellate cell proliferation in vitro and limits fibrogenesis in an in vivo model of liver fibrosis
-
Zhu J, Wu J, Frizell E, et al. Rapamycin inhibits hepatic stellate cell proliferation in vitro and limits fibrogenesis in an in vivo model of liver fibrosis. Gastroenterology 1999; 117(5): 1198.
-
(1999)
Gastroenterology
, vol.117
, Issue.5
, pp. 1198
-
-
Zhu, J.1
Wu, J.2
Frizell, E.3
-
10
-
-
0034789534
-
Rapamycin impairs recovery from acute renal failure: Role of cell-cycle arrest and apoptosis of tubular cells
-
Lieberthal W, Fuhro R, Andry CC, et al. Rapamycin impairs recovery from acute renal failure: role of cell-cycle arrest and apoptosis of tubular cells. Am J Physiol Renal Physiol 2001; 281(4): F693.
-
(2001)
Am J Physiol Renal Physiol
, vol.281
, Issue.4
-
-
Lieberthal, W.1
Fuhro, R.2
Andry, C.C.3
-
11
-
-
0028273536
-
Localization of proliferating cell nuclear antigen, vimentin, c-Fos, and clusterin in the postischemic kidney. Evidence for a heterogenous genetic response among nephron segments, and a large pool of mitotically active and dedifferentiated cells
-
Witzgall R, Brown D, Schwarz C, Bonventre JV. Localization of proliferating cell nuclear antigen, vimentin, c-Fos, and clusterin in the postischemic kidney. Evidence for a heterogenous genetic response among nephron segments, and a large pool of mitotically active and dedifferentiated cells. J Clin Invest 1994; 93(5): 2175.
-
(1994)
J Clin Invest
, vol.93
, Issue.5
, pp. 2175
-
-
Witzgall, R.1
Brown, D.2
Schwarz, C.3
Bonventre, J.V.4
-
12
-
-
0032861113
-
Renal regeneration: Reiterating a developmental paradigm
-
Safirstein R. Renal regeneration: reiterating a developmental paradigm. Kidney Int 1999; 56(4): 1599.
-
(1999)
Kidney Int
, vol.56
, Issue.4
, pp. 1599
-
-
Safirstein, R.1
-
13
-
-
0037836057
-
Dedifferentiation and proliferation of surviving epithelial cells in acute renal failure
-
Bonventre JV. Dedifferentiation and proliferation of surviving epithelial cells in acute renal failure. J Am Soc Nephrol 2003; 14 Suppl 1: S55.
-
(2003)
J Am Soc Nephrol
, vol.14
, Issue.1 SUPPL.
-
-
Bonventre, J.V.1
-
14
-
-
0037378763
-
Delayed graft function and cast nephropathy associated with tacrolimus plus rapamycin use
-
Smith KD, Wrenshall LE, Nicosia RF, et al. Delayed graft function and cast nephropathy associated with tacrolimus plus rapamycin use. J Am Soc Nephrol 2003; 14(4): 1037.
-
(2003)
J Am Soc Nephrol
, vol.14
, Issue.4
, pp. 1037
-
-
Smith, K.D.1
Wrenshall, L.E.2
Nicosia, R.F.3
-
15
-
-
0038666511
-
Sirolimus prolongs recovery from delayed graft function after cadaveric renal transplantation
-
McTaggart RA, Gottlieb D, Brooks J, et al. Sirolimus prolongs recovery from delayed graft function after cadaveric renal transplantation. Am J Transplant 2003; 3(4): 416.
-
(2003)
Am J Transplant
, vol.3
, Issue.4
, pp. 416
-
-
McTaggart, R.A.1
Gottlieb, D.2
Brooks, J.3
-
16
-
-
0347364668
-
Addition of sirolimus to cyclosporine delays the recovery from delayed graft function but does not affect 1-year graft function
-
Stallone G, Di Paolo S, Schena A, et al. Addition of sirolimus to cyclosporine delays the recovery from delayed graft function but does not affect 1-year graft function. J Am Soc Nephrol 2004; 15(1): 228.
-
(2004)
J Am Soc Nephrol
, vol.15
, Issue.1
, pp. 228
-
-
Stallone, G.1
Di Paolo, S.2
Schena, A.3
-
17
-
-
0345161813
-
Sirolimus (rapamycin)-based therapy in human renal transplantation: Similar efficacy and different toxicity compared with cyclosporine
-
Sirolimus European Renal Transplant Study Group
-
Groth CG, Backman L, Morales JM, et al. Sirolimus (rapamycin)-based therapy in human renal transplantation: similar efficacy and different toxicity compared with cyclosporine. Sirolimus European Renal Transplant Study Group. Transplantation 1999; 67(7): 1036.
-
(1999)
Transplantation
, vol.67
, Issue.7
, pp. 1036
-
-
Groth, C.G.1
Backman, L.2
Morales, J.M.3
-
18
-
-
14644403072
-
Benefit-risk assessment of Sirolimus in renal transplantation
-
Kuypers DRJ. Benefit-risk assessment of Sirolimus in renal transplantation. Drug Safety 2005; 28: 153.
-
(2005)
Drug Safety
, vol.28
, pp. 153
-
-
Kuypers, D.R.J.1
-
19
-
-
0033652890
-
A calcineurin inhibitor-sparing regimen with sirolimus, mycophenolate mofetil, and anti-CD25 mAb provides effective immunosuppression in kidney transplant recipients with delayed or impaired graft function
-
Chang GJ, Mahanty HD, Vincenti F, et al. A calcineurin inhibitor-sparing regimen with sirolimus, mycophenolate mofetil, and anti-CD25 mAb provides effective immunosuppression in kidney transplant recipients with delayed or impaired graft function. Clin Transplant 2000; 14(6): 550.
-
(2000)
Clin Transplant
, vol.14
, Issue.6
, pp. 550
-
-
Chang, G.J.1
Mahanty, H.D.2
Vincenti, F.3
-
20
-
-
0026149257
-
Effects of atrial natriuretic factor in ischemic renal injury: Studies in the isolated erythrocyte-perfused rat kidney
-
Lieberthal W. Effects of atrial natriuretic factor in ischemic renal injury: studies in the isolated erythrocyte-perfused rat kidney. Clin Res 1991; 39(2): 157.
-
(1991)
Clin Res
, vol.39
, Issue.2
, pp. 157
-
-
Lieberthal, W.1
-
21
-
-
0028837381
-
Endothelin receptor A blockade alters hemodynamic response to nitric oxide inhibition in rats
-
Thompson A, Valeri CR, Lieberthal W. Endothelin receptor A blockade alters hemodynamic response to nitric oxide inhibition in rats. Am J Physiol 1995; 269 (2 Pt 2): H743.
-
(1995)
Am J Physiol
, vol.269
, Issue.2 PART 2
-
-
Thompson, A.1
Valeri, C.R.2
Lieberthal, W.3
-
22
-
-
0031955170
-
Epithelial cell shedding in acute renal injury
-
Racusen LC. Epithelial cell shedding in acute renal injury. Clin Exp Pharmacol Physiol 1998; 25(3- 4): 273.
-
(1998)
Clin Exp Pharmacol Physiol
, vol.25
, Issue.3-4
, pp. 273
-
-
Racusen, L.C.1
-
23
-
-
21644445328
-
Epidermal growth factor receptor inhibition attenuates early kidney enlargement in experimental diabetes
-
Wassef L, Kelly DJ, Gilbert RE. Epidermal growth factor receptor inhibition attenuates early kidney enlargement in experimental diabetes. Kidney Int 2004; 66(5): 1805.
-
(2004)
Kidney Int
, vol.66
, Issue.5
, pp. 1805
-
-
Wassef, L.1
Kelly, D.J.2
Gilbert, R.E.3
-
24
-
-
0027378020
-
Renal mouse proximal tubular cells are more susceptible than MDCK cells to chemical anoxia
-
Sheridan AM, Schwartz JH, Kroshian VM, et al. Renal mouse proximal tubular cells are more susceptible than MDCK cells to chemical anoxia. Am J Physiol 1993; 265(3 Pt 2): F342.
-
(1993)
Am J Physiol
, vol.265
, Issue.3 PART 2
-
-
Sheridan, A.M.1
Schwartz, J.H.2
Kroshian, V.M.3
-
25
-
-
0030052887
-
Lipid peroxidation contributes to hydrogen peroxide induced cytotoxicity in renal epithelial cells
-
Sheridan AM, Fitzpatrick S, Wang C, et al. Lipid peroxidation contributes to hydrogen peroxide induced cytotoxicity in renal epithelial cells. Kidney Int 1996; 49(1): 88.
-
(1996)
Kidney Int
, vol.49
, Issue.1
, pp. 88
-
-
Sheridan, A.M.1
Fitzpatrick, S.2
Wang, C.3
-
26
-
-
0030665658
-
Lysophosphatidic acid: A novel growth and survival factor for renal proximal tubular cells
-
Levine JS, Koh JS, Triaca V, Lieberthal W. Lysophosphatidic acid: a novel growth and survival factor for renal proximal tubular cells. Am J Physiol 1997; 273(4 Pt 2): F575.
-
(1997)
Am J Physiol
, vol.273
, Issue.4 PART 2
-
-
Levine, J.S.1
Koh, J.S.2
Triaca, V.3
Lieberthal, W.4
-
27
-
-
1642565343
-
Inhibition of ligand-independent ERK1/2 activity in kidney proximal tubular cells deprived of soluble survival factors up-regulates Akt and prevents apoptosis
-
Sinha D, Bannergee S, Schwartz JH, et al. Inhibition of ligand-independent ERK1/2 activity in kidney proximal tubular cells deprived of soluble survival factors up-regulates Akt and prevents apoptosis. J Biol Chem 2004; 279(12): 10962.
-
(2004)
J Biol Chem
, vol.279
, Issue.12
, pp. 10962
-
-
Sinha, D.1
Bannergee, S.2
Schwartz, J.H.3
-
28
-
-
15044342829
-
Lithium activates the Wnt and phosphatidylinositol 3-kinase Akt signaling pathways to promote cell survival in the absence of soluble survival factors
-
Sinha D, Wang Z, Ruchalski KL, et al. Lithium activates the Wnt and phosphatidylinositol 3-kinase Akt signaling pathways to promote cell survival in the absence of soluble survival factors. Am J Physiol Renal Physiol 2005; 288(4): F703.
-
(2005)
Am J Physiol Renal Physiol
, vol.288
, Issue.4
-
-
Sinha, D.1
Wang, Z.2
Ruchalski, K.L.3
-
29
-
-
0037370978
-
Chemical anoxia of tubular cells induces activation of c-Src and its translocation to the zonula adherens
-
Sinha D, Wang Z, Price VR, et al. Chemical anoxia of tubular cells induces activation of c-Src and its translocation to the zonula adherens. Am J Physiol Renal Physiol 2003; 284(3): F488.
-
(2003)
Am J Physiol Renal Physiol
, vol.284
, Issue.3
-
-
Sinha, D.1
Wang, Z.2
Price, V.R.3
-
30
-
-
0037097863
-
Mammalian cell size is controlled by mTOR and its downstream targets S6K1 and 4EBP1/eIF4E
-
Fingar DC, Salama S, Tsou C, et al. Mammalian cell size is controlled by mTOR and its downstream targets S6K1 and 4EBP1/eIF4E. Genes Dev 2002; 16(12): 1472.
-
(2002)
Genes Dev
, vol.16
, Issue.12
, pp. 1472
-
-
Fingar, D.C.1
Salama, S.2
Tsou, C.3
-
31
-
-
0028923877
-
FK506 binding protein 12 mediates sensitivity to both FK506 and rapamycin in murine mast cells
-
Fruman DA, Wood MA, Gjertson CK, et al. FK506 binding protein 12 mediates sensitivity to both FK506 and rapamycin in murine mast cells. Eur J Immunol 1995; 25(2): 563.
-
(1995)
Eur J Immunol
, vol.25
, Issue.2
, pp. 563
-
-
Fruman, D.A.1
Wood, M.A.2
Gjertson, C.K.3
-
32
-
-
0028825698
-
TOR mutations confer rapamycin resistance by preventing interaction with FKBP12-rapamycin
-
Lorenz MC, Heitman J. TOR mutations confer rapamycin resistance by preventing interaction with FKBP12-rapamycin. J Biol Chem 1995; 270(46): 27531.
-
(1995)
J Biol Chem
, vol.270
, Issue.46
, pp. 27531
-
-
Lorenz, M.C.1
Heitman, J.2
-
33
-
-
0032538890
-
Disruption of the p70(s6k)/p85(s6k) gene reveals a small mouse phenotype and a new functional S6 kinase
-
Shima H, Pende M, Chen Y, et al. Disruption of the p70(s6k)/p85(s6k) gene reveals a small mouse phenotype and a new functional S6 kinase. Embo J 1998; 17(22): 6649.
-
(1998)
Embo J
, vol.17
, Issue.22
, pp. 6649
-
-
Shima, H.1
Pende, M.2
Chen, Y.3
-
34
-
-
0346362997
-
Rapamycins: Mechanism of action and cellular resistance
-
Huang S, Bjornsti MA, Houghton PJ. Rapamycins: mechanism of action and cellular resistance. Cancer Biol Ther 2003; 2(3): 222.
-
(2003)
Cancer Biol Ther
, vol.2
, Issue.3
, pp. 222
-
-
Huang, S.1
Bjornsti, M.A.2
Houghton, P.J.3
-
35
-
-
1042267229
-
Determinants of rapamycin sensitivity in breast cancer cells
-
Noh W-C, Mondesire WH, Peng J, et al. Determinants of rapamycin sensitivity in breast cancer cells. Clinical Cancer Research 2004; 10: 1013.
-
(2004)
Clinical Cancer Research
, vol.10
, pp. 1013
-
-
Noh, W.-C.1
Mondesire, W.H.2
Peng, J.3
|