Synthetic approaches to bridgehead nitrogen methanesulfonamide derivatives of 3-amino-2-thioxo-2,3-dihydrothieno[2,3-d]pyrimidin-4(1H)-ones, potential COX-2 selective inhibitors

Journal of Heterocyclic Chemistry

Volumn 43, Issue 4, 2006, Pages 1099-1104

  Granata, Giuseppe ^a   Barbagallo, Salvatore ^a   Perdicaro, Antonio ^a   Marrazzo, Agostino ^a   Santagati, Andrea ^a   Lombardo, Laura ^a   Cardile, Venera ^a  

^a UNIVERSITY OF CATANIA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

3 AMINO 2 THIOXO 2,3 DIHYDROTHIENO[2,3 D]PYRIMIDIN 4(1H) ONE DERIVATIVE; CYCLOOXYGENASE 2 INHIBITOR; INDOMETACIN; N [2 [(2,4 DINITROPHENYL)THIO] 4 OXO 5,6,7,8 TETRAHYDRO[1]BENZOTHIENO[2,3 D]PYRIMIDIN 3(4H) YL]METHANESULFONAMIDE; NITROGEN METHANESULFONAMIDE DERIVATIVE; SULFONAMIDE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CONCENTRATION (PARAMETERS); DRUG SYNTHESIS; ENZYME INHIBITION; ENZYME SPECIFICITY; IN VITRO STUDY; INHIBITION KINETICS; NONHUMAN; STRUCTURE ACTIVITY RELATION;

EID: 33747425203     PISSN: 0022152X     EISSN: None     Source Type: Journal    
DOI: 10.1002/jhet.5570430443     Document Type: Article

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