Effects of Iloprost and pentoxifylline on renal ischemia-reperfusion in rabbit model

European Journal of Medical Research

Volumn 11, Issue 7, 2006, Pages 295-299

  Emrecan, Bilgin ^a,d   Tulukoglu, E ^a   Bozok, S ^a   Kestelli, M ^a   Onem, G ^b   Kupelioglu A ^c   Yagdi, S ^a   Gurbuz A ^a  

^a ATATURK TRAINING AND RESEARCH HOSPITAL   (Turkey)

^b PAMUKKALE UNIVERSITY   (Turkey)

^c DOKUZ EYLUL UNIVERSITY   (Turkey)

^d NONE   (Turkey)

Author keywords

Iloprost; Ischemia reperfusion injury; Pentoxyfillin; Rabbit kidney

Indexed keywords

ILOPROST; MALONALDEHYDE; PENTOXIFYLLINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTINUOUS INFUSION; CONTROLLED STUDY; DRUG MECHANISM; FEMALE; HISTOPATHOLOGY; HYPOTHESIS; KIDNEY ISCHEMIA; KIDNEY PARENCHYMA; KIDNEY TUBULE NECROSIS; MALE; MAXIMUM PERMISSIBLE DOSE; NONHUMAN; RABBIT; RENAL PROTECTION; REPERFUSION; STATISTICAL SIGNIFICANCE;

ANIMALS; DISEASE MODELS, ANIMAL; DRUG THERAPY, COMBINATION; FEMALE; ILOPROST; KIDNEY; KIDNEY CORTEX; KIDNEY TUBULES; LIPID PEROXIDATION; MALE; MALONDIALDEHYDE; PENTOXIFYLLINE; PLATELET AGGREGATION INHIBITORS; RABBITS; REPERFUSION INJURY; SEVERITY OF ILLNESS INDEX; TREATMENT OUTCOME; VASODILATOR AGENTS;

EID: 33747240744     PISSN: 09492321     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (26)

1. Fantone JC, Marasco WA, Elgas LJ, Ward PA. Stimulus specificity of prostaglandin inhibition of rabbit polymorphonuclear leukocyte lysosomal enzyme release and superoxide anion production. Am J Pathol 1984;115:9-16.
2. Simpson PJ, Mitsos SE, Ventura A, et al. Prostacyclin protects ischemic reperfused myocardium in the dog by inhibition of neutrophil activation. Am Heart J 1987;113:129-37.
3. Kishi M, Tanaka H, Seiyama A, Takaoka M, Matsuoka T, Yoshioka T, et al. Pentoxifylline attenuates reperfusion injury in skeletal muscle after partial ischemia. Am J Physiol Heart Circ Physiol 1998;274:1435-42
4. Adams JG Jr, Dhar A, Shukla SD, Silver D.. Effect of pentoxifylline on tissue injury and platelet-activating factor production during ischemia-reperfusion injury. J. Vasc. Surg. 1995;21:742-8
5. Kim YK, Yoo JH, Woo JS, Jung JS, Kim BS, Kim SY. Effect of pentoxifylline on ischemic acute renal failure in rabbits. Ren Fail. 2001;23(6):757-72
6. Onal A, Astarcioglu H, Ormen M, Atila K, Sarioglu S. The beneficial effect of L-carnitine in rat renal ischemia-reperfusion injury] Ulus Travma Derg. 2004;10(3):160-7
7. Uchiyama, M.; Mihara, M. Determination of malonaldehyde precursor in tissues by thiobarbituric acid test. Anal. Biochem. 1978;86:271-8
8. Mohan C, Marini C, Gennaro M, Ascer E. The value and limitation of iloprost infusion in decreasing skeletal muscle necrosis. J Vasc Surg. 1992;16(2):268-73
9. Belkin M, Wright JG, Hobson RW. Iloprost infusion decreases skeletal muscle ischemia-reperfusion injury. J Vasc Surg 1990;11:77-83.
10. Fitzl G, Winkler D, Wassilev G, Welt K. The protective effect of iloprost, a PGL2 analogue, on ultratructure of ischemic and reperfused myocardial myocytes. Exp Toxicol Pathol. 1999;51(1):81-8.
11. Kawashima M, Nakamura T, Schneider S, Vollmar B, Lausberg HF, Bauer M, et al. Iloprost ameliorates post-ischemic lung reperfusion injury and maintains an appropriate pulmonary ET-1 balance. J Heart Lung Transplant. 2003;22(7):794-801.
12. Katircioglu SF, Ulus AT, Gokce P, Surucu S. Iloprost protects the spinal cord during aortic cross-clamping in a canine model. J Cardiovasc Surg. 2000;41(1):89-93
13. Silistreli E, Kabakci B, Yilmaz E, Sonmez A, Erdal C, Karabay O, et al. Early protective effects of iloprost, a stable prostacyclin analog, during spinal cord ischemia in a rabbit model. Heart Vessels. 2005;20(2):66-71.
14. Dosluoglu HH, Aktan AO, Yegen C, Okboy N, Yalcm AS, Yahn R, et al.The cytoprotective effects of verapamil and iloprost (ZK 36374) on ischemia/ reperfusion injury of kidneys. Transpl Int. 1993;6(3):138-42
15. Kim YK, Choi TR, Kwon CH, Kim JH, Woo JS, Jung JS. Beneficial effect of pentoxifylline on cisplatin-induced acute renal failure in rabbits. Ren Fail. 2003;25(6):909-22.
16. Ciuffetti G, Mercuri M, Ott C, Lombardini R, Paltriccia R, Lupattelli G, et al. Use of pentoxifylline as an inhibitor of free radical generation in peripheral vascular disease. Results of a double-blind placebo-controlled study. Eur. J. Clin. Pharmacol. 1991;41; 511-5
17. Berens KL, Luke DR. Pentoxifylline in the isolated perfused rat kidney. Transplantation. 1990;49(5):876-9
18. Kihara M, Nickander KR, Low PA. The effect of aging on endoneurial blood flow, hyperemic response and oxygen-free radicals in rat sciatic nerve. Brain Res. 1991;18;562(1)1-5.
19. Veveris M, Dambrova M, Cirule H, Meirena D, Kalvinsh I, Wikberg JE. Cardioprotective effects of N-hydroxyguanidine PR5 in myocardial ischaemia and reperfusion in rats. Br J Pharmacol. 1999;128(5):1089-97.
20. Kabasakal L, Sehirli O, Cetinel S, Cikler E, Gedik N, Sener G. Protective effect of aqueous garlic extract against renal ischemia/ reperfusion injury in rats. J Med Food. 2005;8(3):319-26
21. Erkasap S, Ates E. L-Arginine-enriched preservation solution decreases ischaemia/reperfusion injury in canine kidneys after long-term cold storage. Nephrol Dial Transplant. 2000;15(8):1224-7.
22. Schoenberg MH, Beger HG. Reperfusion injury after intestinal ischemia. Crit Care Med. 1993;21(9):1376-86. Review
23. Savas S, Delibas N, Savas C, Sutcu R, Cindas A. Pentoxifylline reduces biochemical markers of ischemia-reperfusion induced spinal cord injury in rabbits. Spinal Cord. 2002;40(5):224-9
24. Cetinkale O, Bilgic L, Bolayirli M, Sengul R, Ayan F, Burcak G. Involvement of neutrophils in ischemia-reperfusion injury of inguinal island skin flaps in rats. Plast Reconstr Surg. 1998;102(1):153-60
25. Kihara M, Nickander KK, Low PA. The effect of aging on endoneurial blood flow, hyperemic response and oxygen-free radicals in rat sciatic nerve. Brain Res. 1991;18;562(1):1-5
26. Veveris M, Dambrova M, Cirule H, Meirena D, Kalvinsh I, Wikberg JE. Cardioprotective effects of N-hydroxyguanidine PR5 in myocardial ischaemia and reperfusion in rats. Br J Pharmacol. 1999;128(5):1089-97