Sequential accumulation of the basal core promoter and the precore mutations in the progression of hepatitis B virus-related chronic liver disease

Intervirology

Volumn 49, Issue 5, 2006, Pages 266-273

  Song, Byung Cheol ^a   Xiu, Ji Cui ^a   Heung, Up Kim ^a   Cho, Yoo Kyung ^a  

^a Jeju National University School of Medicine   (South Korea)

Author keywords

Basal core promoter mutation; Chronic hepatitis B; Genotype; Hepatitis B virus; Precore mutation

Indexed keywords

ADULT; ARTICLE; CHRONIC HEPATITIS; CHRONIC LIVER DISEASE; CLINICAL ARTICLE; DNA REPLICATION; FEMALE; GENOTYPE; HEPATITIS B VIRUS; HUMAN; IMMUNOLOGICAL TOLERANCE; LIVER CIRRHOSIS; MALE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROMOTER REGION; TRANSCRIPTION REGULATION; VIRUS CARRIER; VIRUS CORE; VIRUS MUTATION;

ADULT; CARRIER STATE; DISEASE PROGRESSION; FEMALE; HEPATITIS B; HEPATITIS B CORE ANTIGENS; HEPATITIS B E ANTIGENS; HEPATITIS B SURFACE ANTIGENS; HEPATITIS B, CHRONIC; HUMANS; LIVER CIRRHOSIS; MALE; MIDDLE AGED; MUTATION; POLYMERASE CHAIN REACTION; PROMOTER REGIONS (GENETICS); SPECIES SPECIFICITY;

HEPATITIS B VIRUS;

EID: 33747240133     PISSN: 03005526     EISSN: None     Source Type: Journal    
DOI: 10.1159/000093456     Document Type: Article

References (49)

1. Locarnini S, McMillan J, Bartholomeusz A: The hepatitis B virus and common mutants. Semin Liver Dis 2003;23:5-20.
2. Brunetto MR, Stemler M, Schodel F, Will H, Ottobrelli A, Rizzetto M, Verme G, Bonino F: Identification of HBV variants which cannot produce precore derived HBeAg and may be responsible for severe hepatitis. Ital J Gastroenterol 1989;21:151-154.
3. Carman WF, Jacyna MR, Hadziyannis S, Karayiannis P, McGarvey MJ, Makris A, Thomas HC: Mutation preventing formation of hepatitis B e antigen in patients with chronic hepatitis B infection. Lancet 1989;ii:588-591.
4. Brunetto MR, Stemler M, Bonino F, Schodel F, Oliveri F, Rizzetto M, Verme G, Will H: A new hepatitis B virus strain in patients with severe anti-HBe positive chronic hepatitis B. J Hepatol 1990;10:258-261.
5. Carman WF, Fagan EA, Hadziyannis S, Karayiannis P, Tassopoulos NC, Williams R, Thomas HC: Association of a precore genomic variant of hepatitis B virus with fulminant hepatitis. Hepatology 1991;14:219-222.
6. Liang TJ, Hasegawa K, Rimon N, Wands JR, Ben-Porath E: A hepatitis B virus mutant associated with an epidemic of fulminant hepatitis. N Engl J Med 1991;324:1705-1709.
7. Omata M, Ehata T, Yokosuka O, Hosoda K, Ohto M: Mutations in the precore region of hepatitis B virus DNA in patients with fulminant and severe hepatitis. N Engl J Med 1991;324:1699-1704.
8. Okamoto H, Tsuda F, Akahane Y, Sugai Y, Yoshiba M, Moriyama K, Tanaka T, Miyakawa Y, Mayumi M: Hepatitis B virus with mutations in the core promoter for an e antigen-negative phenotype in carriers with antibody to e antigen. J Virol 1994;68:8102-8110.
9. Takahashi K, Aoyama K, Ohno N, Iwata K, Akahane Y, Baba K, Yoshizawa H, Mishiro S: The precore/core promoter mutant (T1762A1764) of hepatitis B virus: clinical significance and an easy method for detection. J Gen Virol 1995;76:3159-3164.
10. Yuh CH, Chang YL, Ting LP: Transcriptional regulation of precore and pregenomic RNAs of hepatitis B virus. J Virol 1992;66:4073-4084.
11. Chen IH, Huang CJ, Ting LP: Overlapping initiator and TATA box functions in the basal core promoter of hepatitis B virus. J Virol 1995;69:3647-3657.
12. Kramvis A, Kew MC: The core promoter of hepatitis B virus. J Viral Hepatol 1999;6:415-427.
13. Kidd-Ljunggren K, Oberg M, Kidd AH: Hepatitis B virus X gene 1751 to 1764 mutations: Implications for HBeAg status and disease. J Gen Virol 1997;78:1469-1478.
14. Takahashi K, Akahane Y, Hino K, Ohta Y, Mishiro S: Hepatitis B virus genomic sequence in the circulation of hepatocellular carcinoma patients: Comparative analysis of 40 full-length isolates. Arch Virol 1998;143:2313-2326.
15. Takahashi K, Ohta Y, Kanai K, Akahane Y, Iwasa Y, Hino K, Ohno N, Yoshizawa H, Mishiro S: Clinical implications of mutations C-to-T1653 and T-to-C/A/G1753 of hepatitis B virus genotype C genome in chronic liver disease. Arch Virol 1999;144:1299-1308.
16. Tur-Kaspa R, Klein A, Aharonson S: Hepatitis B virus precore mutants are identical in carriers from various ethnic origins and are associated with a range of liver disease severity. Hepatology 1992;16:1338-1342.
17. Rodriguez-Frias F, Buti M, Jardi R, Cotrina M, Viladomiu L, Esteban R, Guardia J: Hepatitis B virus infection: precore mutants and its relation to viral genotypes and core mutations. Hepatology 1995;22:1641-1647.
18. Chan HL, Leung NW, Hussain M, Wong ML, Lok AS: Hepatitis B e antigen-negative chronic hepatitis B in Hong Kong. Hepatology 2000;31:763-768.
19. Laskus T, Persing DH, Nowicki MJ, Mosley JW, Rakela J: Nucleotide sequence analysis of the precore region in patients with fulminant hepatitis B in the United States. Gastroenterology 1993;105:1173-1178.
20. Liu CJ, Kao JH, Lai MY, Chen PJ, Chen DS: Precore/core promoter mutations and genotypes of hepatitis B virus in chronic hepatitis B patients with fulminant or subfulminant hepatitis. J Med Virol 2004;72:545-550.
21. Akarca US, Greene S, Lok AS: Detection of precore hepatitis B virus mutants in asymptomatic HBsAg-positive family members. Hepatology 1994;19:1366-1370.
22. Buckwold VE, Xu Z, Chen M, Yen TS, Ou JH: Effects of a naturally occurring mutation in the hepatitis B virus basal core promoter on precore gene expression and viral replication. J Virol 1996;70:5845-5851.
23. Moriyama K, Okamoto H, Tsuda F, Mayumi M: Reduced precore transcription and enhanced core-pregenome transcription of hepatitis B virus DNA after replacement of the precore-core promoter with sequences associated with e antigen-seronegative persistent infections. Virology 1996;226:269-280.
24. Buckwold VE, Xu Z, Yen TS, Ou JH: Effects of a frequent double-nucleotide basal core promoter mutation and its putative single-nucleotide precursor mutations on hepatitis B virus gene expression and replication. J Gen Virol 1997;78:2055-2065.
25. Sato S, Suzuki K, Akahane Y, Akamatsu K, Akiyama K, Yunomura K, Tsuda F, Tanaka T, Okamoto H, Miyakawa Y, et al: Hepatitis B virus strains with mutations in the core promoter in patients with fulminant hepatitis. Ann Intern Med 1995;122:241-248.
26. Friedt M, Gerner P, Lausch E, Trubel H, Zabel B, Wirth S: Mutations in the basic core promotor and the precore region of hepatitis B virus and their selection in children with fulminant and chronic hepatitis B. Hepatology 1999;29:1252-1258.
27. Lindh M, Hannoun C, Dhillon AP, Norkrans G, Horal P: Core promoter mutations and genotypes in relation to viral replication and liver damage in East Asian hepatitis B virus carriers. J Infect Dis 1999;179:775-782.
28. Laskus T, Rakela J, Nowicki MJ, Persing DH: Hepatitis B virus core promoter sequence analysis in fulminant and chronic hepatitis B. Gastroenterology 1995;109:1618-1623.
29. Sterneck M, Gunther S, Santantonio T, Fischer L, Broelsch CE, Greten H, Will H: Hepatitis B virus genomes of patients with fulminant hepatitis do not share a specific mutation. Hepatology 1996;24:300-306.
30. Chun YK, Kim JY, Woo HJ, Oh SM, Kang I, Ha J, Kim SS: No significant correlation exists between core promoter mutations, viral replication, and liver damage in chronic hepatitis B infection. Hepatology 2000;32:1154-1162.
31. Lindh M, Andersson AS, Gusdal A: Genotypes, nt 1858 variants, and geographic origin of hepatitis B virus: large-scale analysis using a new genotyping method. J Infect Dis 1997;175:1285-1293.
32. Orito E, Ichida T, Sakugawa H, Sata M, Horiike N, Hino K, Okita K, Okanoue T, Iino S, Tanaka E, Suzuki K, Watanabe H, Hige S, Mizokami M: Geographic distribution of hepatitis B virus (HBV) genotype in patients with chronic HBV infection in Japan. Hepatology 2001;34:590-594.
33. Miyakawa Y, Mizokami M: Classifying hepatitis B virus genotypes. Intervirology 2003;46:329-338.
34. Song BC, Cui XJ, Kim H: Hepatitis B virus genotypes in Korea: An endemic area of hepatitis B virus infection. Intervirology 2005;48:133-137.
35. Kao JH, Chen PJ, Lai MY, Chen DS: Hepatitis B genotypes correlate with clinical outcomes in patients with chronic hepatitis B. Gastroenterology 2000;118:554-559.
36. Chu CJ, Hussain M, Lok AS: Hepatitis B virus genotype B is associated with earlier HBeAg seroconversion compared with hepatitis B virus genotype C. Gastroenterology 2002;122:1756-1762.
37. Sanchez-Tapias JM, Costa J, Mas A, Bruguera M, Rodes J: Influence of hepatitis B virus genotype on the long-term outcome of chronic hepatitis B in western patients. Gastroenterology 2002;123:1848-1856.
38. Sugauchi F, Chutaputti A, Orito E, Kato H, Suzuki S, Ueda R, Mizokami M: Hepatitis B virus genotypes and clinical manifestation among hepatitis B carriers in Thailand. J Gastroenterol Hepatol 2002;17:671-676.
39. Chan HL, Wong ML, Hui AY, Hung LC, Chan FK, Sung JJ: Hepatitis B virus genotype C takes a more aggressive disease course than hepatitis B virus genotype B in hepatitis B e antigen-positive patients. J Clin Microbiol 2003;41:1277-1279.
40. Nakayoshi T, Maeshiro T, Nakasone H, Sakugawa H, Kinjo F, Orito E, Mizokami M: Difference in prognosis between patients infected with hepatitis B virus with genotype B and those with genotype C in the Okinawa Islands: a prospective study. J Med Virol 2003;70:350-354.
41. Sumi H, Yokosuka O, Seki N, Arai M, Imazeki F, Kurihara T, Kanda T, Fukai K, Kato M, Saisho H: Influence of hepatitis B virus genotypes on the progression of chronic type B liver disease. Hepatology 2003;37:19-26.
42. Chan HL, Hui AY, Wong ML, Tse AM, Hung LC, Wong VW, Sung JJ: Genotype C hepatitis B virus infection is associated with an increased risk of hepatocellular carcinoma. Gut 2004;53:1494-1498.
43. Chan HL, Hussain M, Lok AS: Different hepatitis B virus genotypes are associated with different mutations in the core promoter and precore regions during hepatitis B e antigen seroconversion. Hepatology 1999;29:976-984.
44. Orito E, Mizokami M, Sakugawa H, Michitaka K, Ishikawa K, Ichida T, Okanoue T, Yotsuyanagi H, Iino S: A case-control study for clinical and molecular biological differences between hepatitis B viruses of genotypes B and C. Japan HBV Genotype Research Group. Hepatology 2001;33:218-223.
45. Fattovich G: Natural history of hepatitis B. J Hepatol 2003;39(suppl 1):S50-58.
46. Lok AS, McMahon BJ: Chronic hepatitis B. Hepatology 2001;34:1225-1241.
47. Bruix J, Castells A, Bosch J, Feu F, Fuster J, Garcia-Pagan JC, Visa J, Bru C, Rodes J: Surgical resection of hepatocellular carcinoma in cirrhotic patients: Prognostic value of preoperative portal pressure. Gastroenterology 1996;111:1018-1022.
48. Di Lelio A, Cestari C, Lomazzi A, Beretta L: Cirrhosis: diagnosis with sonographic study of the liver surface. Radiology 1989;172:389-392.
49. Naito H, Hayashi S, Abe K: Rapid and specific genotyping system for hepatitis B virus corresponding to six major genotypes by PCR using type-specific primers. J Clin Microbiol 2001;39:362-364.