Expression pattern of osteopontin in endometrial carcinoma: Correlation with expression of the adhesion molecule CEACAM1

International Journal of Gynecological Pathology

Volumn 25, Issue 2, 2006, Pages 161-169

  Briese, Juliane ^a   Schulte, Heinrich M ^b   Bamberger, Christoph M ^c   Löning, Thomas ^a   Bamberger, Ana Maria ^a  

^a UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

^b ENDOKRINOLOGIKUM HAMBURG   (Germany)

^c NONE

Author keywords

CEACAM1; Endometrial cancer; Endometrium; Osteopontin; Uterus

Indexed keywords

CARCINOEMBRYONIC ANTIGEN RELATED CELL ADHESION MOLECULE 1; CELL ADHESION MOLECULE; OSTEOPONTIN; TUMOR MARKER; CD66 ANTIGENS; LEUKOCYTE ANTIGEN; SIALOGLYCOPROTEIN; SPP1 PROTEIN, HUMAN;

ANTIBODY SPECIFICITY; ARTICLE; CARCINOGENESIS; CLEAR CELL CARCINOMA; CONTROLLED STUDY; CYTOPLASM; ENDOMETRIOID CARCINOMA; ENDOMETRIUM CARCINOMA; ENDOMETRIUM HYPERPLASIA; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOFLUORESCENCE TEST; IMMUNOHISTOCHEMISTRY; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; WESTERN BLOTTING; ADENOCARCINOMA; CHEMISTRY; CYTOLOGY; ENDOMETRIUM; ENDOMETRIUM TUMOR; FLUORESCENT ANTIBODY TECHNIQUE; METABOLISM; PATHOLOGY; PHYSIOLOGY;

ADENOCARCINOMA, SCIRRHOUS; ANTIGENS, CD; BLOTTING, WESTERN; CARCINOMA, ENDOMETRIOID; CELL ADHESION MOLECULES; ENDOMETRIAL HYPERPLASIA; ENDOMETRIAL NEOPLASMS; ENDOMETRIUM; FEMALE; FLUORESCENT ANTIBODY TECHNIQUE; HUMANS; IMMUNOHISTOCHEMISTRY; OSTEOPONTIN; SIALOGLYCOPROTEINS; TUMOR MARKERS, BIOLOGICAL;

EID: 33747202221     PISSN: 02771691     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.pgp.0000189243.49522.ae     Document Type: Article

References (45)

1. Landis SH, Murray T, Bolden S, et al. Cancer statistics. CA Cancer J Clin 1999;49:8-31.
2. Matias-Guiu X, Catasus L, Bussaglia E, et al. Molecular pathology of endometrial hyperplasia and carcinoma. Hum Pathol 2001;32:569-77.
3. Liaw L, Almeida M, Hart CE, et al. The adhesive and migratory effects of osteopontin are mediated via distinct cell surface integrins: role of alpha v beta 3 in smooth muscle cell migration to osteopontin in vitro. J Clin Invest 1995;95:713-24.
4. Daiter E, Omigbodun A, Wang S, et al. Cell differentiation and endogenous cyclic adenosine 3′5′-Monophosphate regulate osteopontin expression in human trophoblasts. Endocrinology 1996;137:1785-90.
5. Yue TL, McKenna PJ, Ohlstein EH, et al. Osteopontin-stimulated vascular smooth muscle cell migration is mediated by beta 3 integrin. Exp Cell Res 1994;214:459-64.
6. Reinholt FP, Hultenby K, Oldenberg A, et al. Osteopontin: a possible anchor of Osteoclasts to bone. Proc Natl Acad Sci USA 1990;87:4473-5.
7. Giachelli CM, Steitz S. Osteopontin: a versatile regulator of inflammation and biomineralization. Matrix Biol 2000;19:615-22.
8. Johnson GA, Burghardt RC, Bazer FW, et al. Osteopontin: roles in implantation and placentation. Biol Reprod 2003;69:1458-71.
9. Brown LF, Berse B, Van de Water L, et al. Expression and distribution of osteopontin in human tissues. Biol Cell 1992;3:1169-80.
10. Rittling SR, Novick KE. Osteopontin expression in mammary gland development and tumorigenesis. Cell Growth Differ 1997;8:1010-69.
11. Senger DR, Peruzzi CA, Papadopoulos A. Elevated expression of secreted phosphoprotein I (osteopontin 2ar) as a consequence of neoplastic transformation. Anticancer Res 1989;9:1291-300.
12. Senger DR, Asch BB, Smith BD, et al. A secreted phosphoprotein marker for neoplastic transformation of both epithelial and fibroblastic cells. Nature 1983;302:714-5.
13. Craig AM, Nemir M, Mukherjee BB, et al. Identification of the major phosphoprotein secreted by many rodent cell lines as 2ar/osteopontin: enhanced expression in H-ras-transformed 3T3 cells. Biochem Biophys Res Commun 1988;157:166-73.
14. Craig AM, Bowden GT, Chambers AF, et al. Secreted phosphoprotein mRNA is induced during multi-stage carcinogenesis in mouse skin and correlates with the metastatic potential of murine fibroblasts. Int J Cancer 1990;46:133-7.
15. Chambers AF, Behrend EI, Wilson SM, et al. Induction of expression of osteopontin (OPN; secreted phosphoprotein) in metastatic, ras-transformed NIH 3T3 cells. Anticancer Res 1992;12:43-8.
16. Oates AJ, Barraclough R, Rudland PS. The identification of osteopontin as a metastasis-related gene product in a rodent mammary tumor model. Oncogene 1996;13:97-104.
17. Singhal H, Bautista DS, Tonkin KS, et al. Elevated plasma osteopontin in metastatic breast cancer associated with increased tumor burden and decreased survival. Clin Cancer Res 1997;3:605-11.
18. Fedarko NS, Jain A, Karadag A, et al. Elevated serum bone sialoprotein and osteopontin in colon, breast, prostate, and lung cancer. Clin Cancer Res 2001;7:4060-6.
19. Hotte SJ, Winquist EW, Stitt L, et al. Plasma osteopontin: associations with survival and metastasis to bone in men with hormone-refractory prostate carcinoma. Cancer 2002;95:506-12.
20. Thompson J, Grunert F, Zimmermann W. Carcinoembryonic antigen family: molecular biology and clinical perspectives. J Clin Lab Anal 1991;5:344-66.
21. Beauchemin N, Draber P, Dveksler G, et al. Redefined nomenclature for members of the carcinoembryonic antigen family. Exp Cell Res 1999;86:267-72.
22. Lin SH, Giudotti G. Cloning and expression of a cDNA coding for a rat liver plasma membrane ecto-ATPase: the primary structure of ectoATPase is similar to that of the human biliary glycoprotein I. J Biol Chem 1989;264:14408-14.
23. Aurivilius M, Hansen OC, Lazrek MB, et al. The cell adhesion molecule Cell-CAM 105 is an ectoATPase and a member of the immunoglobulin superfamily. FEBS Lett 1990;264:267-9.
24. Kuijpers TW, Hoogerwerf M, Van der Laan LJ, et al. CD66 nonspecific cross-reacting antigens are involved in neutrophil adherence to cytocine-activated endothelial cells. J Cell Biol 1992;118:457-66.
25. Barnett HT, Kretschmer A, Austen DA, et al. Carcinoembryonic antigens: alternative splicing accounts for the multiple mRNAs that code for novel members of the carcinoembryonic antigen family. J Cell Biol 1989;108:267-76.
26. Brümmer J, Neumaier M, Göpfert C, et al. Association of the pp60c-src with biliary Glycoprotein (CD66a), an adhesion molecule of the carcinoembryonic antigen family down Regulated in colonic carcinomas. Oncogene 1995;11:1649-55.
27. Brümmer J, Ebrahimnejad A, Flayeh R, et al. Cis interaction of the cell adhesion molecule CEACAM1 with integrin beta3. Am J Pathol 2001;159:537-46.
28. Damsky CH, Librach C, Lim KH, et al. Intergrin switching regulates normal trophoblast invasion. Development 1994;120:3657-66.
29. Bamberger AM, Riethdorf L, Nollau P, et al. Dysregulated expression of CD66a (BGP, C-CAM), an Adhesion molecule of the CEA family, in endometrial cancer. Am J Pathol 1998;152:1401-06.
30. Drzeniek Z, Lamerz R, Fenger U, et al. Identification of membrane Antigens in granulocytes and colonic carcinoma cells by a monoclonal antibody specific for biliary glycoprotein, a member of the carcinoembryonic antigen family. Cancer Lett 1991;56:173-9.
31. Stoffel A, Neumaier M, Gaida FJ, et al. Monoclonal anti-domain, and anti-peptide antibodies assign the molecular weight 160.000 granulocyte membrane antigen of the CD66 cluster to a mRNA species encoded by the biliary glycoproteine gene, a member of the carcinoembryonic antigen gene family. J Immunol 1993;150:4978-84.
32. Prall F, Nollau P, Neumaier M, et al. CD66a (BGP), an adhesion molecule of the carcinoembryonic antigen family is expressed in epithelium, endothelium, and myeloid cells in a wide range of normal human tissues. J Histochem Cytochem 1996;44:35-41.
33. Bamberger AM, Sudahl S, Löning T, et al. The adhesion molecule CEACAM1 (CD66a, C-CAM, BGP) is specifically expressed by the extravillous intermediate trophoblast. Am J Pathol 2000;156:1165-70.
34. Clarke CL, Sutherland RL. Progestin regulation of cellular proliferation. Endocr Rev 1991;11:266-301.
35. Coppola D, Szabo M, Boulware D, et al. Correlation of osteopontin protein expression and pathological stage across a wide variety of tumor histologies. Clin Cancer Res 2004;10:184-90.
36. Briese J, Oberndörfer M, Pätschenik C et al. Osteopontin (OPN) is colocalized with the adhesion molecule CEACAM1 in the extravillous trophoblast of the human placenta and enhances invasion of CEACAM1-expressing placental cells. J Clin Endocrinol Metab 2005;90:5407-13.
37. Briese J, Oberndörfer M, Schulte HM, et al. Osteopontin (OPN) expression in gestational trophoblastic diseases (GTD)-correlation with expression of the adhesion molecule CEACAM1. Int J Gynecol Pathol 2005;24:271-6.
38. Lax SF. Molecular genetic pathways in various types of endometrial carcinoma: from a phenotypical to a molecular-based classification. Virchows Arch 2004;444:213-23.
39. Lasa M, Chang PL, Prince CW, et al. Phosphorylation of osteopontin by Golgi apparatus casein kinase. Biochem Biophys Res Commun 1997;240:602-5.
40. 2+ influx. J Biol Chem 1998a;273:29935-41.
41. Quin C, Brunn JC, Jones J, et al. A comparative study of sialic acid-rich proteins in rat bone and dentin. Eur J Oral Sci 2001a;109:133-41.
42. Liaw L, Skinner MP, Reines EW, et al. The adhesive and migratory effects of osteopontin are mediated via distinct cell surface integrins. J Clin Invest 1995;95:713-24.
43. Kim JH, Skates SJ, Uede T, et al. Osteopontin as a potential diagnostic biomarker for ovarian cancer. JAMA 2002;287:1671-9.
44. Brown LF, Papadopoulos-Sergiou A, Berse B, et al. Osteopontin expression and distribution in human carcinomas. Am J Pathol 1994;145:610-23.
45. Kunath T, Ordonez-Garcia C, Turbide C, et al. Inhibition of colonic tumor cell growth by biliary glycoprotein. Oncogene 1995;11:2375-82.