Effects on gene expressions of G protein alpha subunits by activation of non-neuronal muscarinic receptor

Chinese Pharmacological Bulletin

Volumn 22, Issue 6, 2006, Pages 664-667

  Chen, Kai ^a   Wang, Hai ^a  

^a BEIJING INSTITUTE OF MICROBIOLOGY AND EPIDEMIOLOGY   (China)

Author keywords

Carbachol; Endothelial cells; G protein; Non neuronal muscarinic receptor; Pilocarpine

Indexed keywords

CARBACHOL; GUANINE NUCLEOTIDE BINDING PROTEIN ALPHA SUBUNIT; MESSENGER RNA; MUSCARINIC RECEPTOR; PILOCARPINE; RNA;

ANIMAL CELL; ARTICLE; CELL CULTURE; ENDOTHELIUM CELL; GENE EXPRESSION; NONHUMAN; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA EXTRACTION; SIGNAL TRANSDUCTION; UPREGULATION;

EID: 33747191494     PISSN: 10011978     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (10)

1. Furchgott R F, Zawadzki J V. The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine [J]. Nature, 1980, 288(2):373-6.
2. Raitakari O T, Celermajer D S. Testing for endothelial dysfunction [J]. Ann Med, 2000, 32(2):293-304.
3. Shan L M, Wang H. Pharmacological characteristics of endothelial target for acetylcholine [J]. Life Sci, 2002, 70(2):1285-98.
4. Patil P N, Stearns R. Mechanism of vascular relaxation by cholinomimetic drugs with special reference to pilocarpine and arecoline [J]. J Ocul Pharmacol Ther, 2002, 18(1):25-34.
5. Sawyer B D, Bynaster F P, Calligaro D O, et al. Direct pharmacological comparison of the muscarinic receptors mediating relaxation and contraction in the rabbit thoracic aorta [J]. Gener Pharmacol, 1999, 329:445-52.
6. Shah B H. Cholera toxin mediated regulation of the expression of Gqα and G11α GTP binding proteins [J]. Exp Mol Med, 1999, 31(2):89-94.
7. Kaewsuk S, Hutamekalin P, Ketterman AJ, et al. Morphine induces short-lived changes in G-protein gene expression in rat prefrontal cortex [J]. Eur J Pharmacol, 2001, 4111(1):11-6.
8. Lanzafame A A, Christopoulos A, Mitchelson F. Cellular signaling mechanism for muscarinic acetylcholine receptors [J]. Receptors Channels, 2003, 9(4):241-60.
9. van Koppen C J, Kaiser B. Regulation of muscarinic acetylcholine receptor signaling [J]. Pharmacol Ther, 2003, 98(2):197-220.