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Volumn 45, Issue 31, 2006, Pages 9624-9631

Electron microscopic visualization of telomerase from Euplotes aediculatus bound to a model telomere DNA

Author keywords

[No Author keywords available]

Indexed keywords

BINDERS; BIOCHEMISTRY; DIMERS; ELECTRON MICROSCOPY; FILTRATION; PROTEINS;

EID: 33747110274     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi060313s     Document Type: Article
Times cited : (9)

References (34)
  • 2
    • 0019568388 scopus 로고
    • All gene-sized DNA molecules in four species of hypotrichs have the same terminal sequence and an unusual 3′ terminus
    • Klobutcher, L. A., Swanton, M. T., Donini, P., and Prescott, D. M. (1981) All gene-sized DNA molecules in four species of hypotrichs have the same terminal sequence and an unusual 3′ terminus, Proc. Natl. Acad. Sci. U.S.A. 78, 3015-9.
    • (1981) Proc. Natl. Acad. Sci. U.S.A. , vol.78 , pp. 3015-3019
    • Klobutcher, L.A.1    Swanton, M.T.2    Donini, P.3    Prescott, D.M.4
  • 3
    • 0024573115 scopus 로고
    • An overhanging 3′ terminus is a conserved feature of telomeres
    • Henderson, B. R., and Blackburn, E. H. (1989) An overhanging 3′ terminus is a conserved feature of telomeres, Mol. Cell. Biol. 9, 345-8.
    • (1989) Mol. Cell. Biol. , vol.9 , pp. 345-348
    • Henderson, B.R.1    Blackburn, E.H.2
  • 4
    • 0015515155 scopus 로고
    • Origin of concatemeric T7 DNA
    • Watson, J. D. (1972) Origin of concatemeric T7 DNA, Nat. New Biol. 239, 197-201.
    • (1972) Nat. New Biol. , vol.239 , pp. 197-201
    • Watson, J.D.1
  • 5
    • 0015844590 scopus 로고
    • A theory of marginotomy. The incomplete copying of template margin in enzymic synthesis of polynucleotides and biological significance of the phenomenon
    • Olovnikov, A. M. (1973) A theory of marginotomy. The incomplete copying of template margin in enzymic synthesis of polynucleotides and biological significance of the phenomenon, J. Theor. Biol. 41, 181-90.
    • (1973) J. Theor. Biol. , vol.41 , pp. 181-190
    • Olovnikov, A.M.1
  • 6
  • 7
    • 0022402513 scopus 로고
    • Identification of a specific telomere terminal transferase activity in Tetrahymena extracts
    • Greider, C. W., and Blackburn, E. H. (1985) Identification of a specific telomere terminal transferase activity in Tetrahymena extracts, Cell 43, 405-13.
    • (1985) Cell , vol.43 , pp. 405-413
    • Greider, C.W.1    Blackburn, E.H.2
  • 8
    • 0025914141 scopus 로고
    • Telomerase is processive
    • Greider, C. W. (1991) Telomerase is processive, Mol. Cell. Biol. 11, 4572-80.
    • (1991) Mol. Cell. Biol. , vol.11 , pp. 4572-4580
    • Greider, C.W.1
  • 9
    • 4644354584 scopus 로고    scopus 로고
    • Adding to the ends: What makes telomerase processive and how important is it?
    • Lue, N. F. (2004) Adding to the ends: What makes telomerase processive and how important is it? BioEssays 26, 955-62.
    • (2004) BioEssays , vol.26 , pp. 955-962
    • Lue, N.F.1
  • 10
    • 0034964393 scopus 로고    scopus 로고
    • Analysis of telomerase processivity: Mechanistic similarity to HIV-1 reverse transcriptase and role in telomere maintenance
    • Peng, Y., Mian, I. S., and Lue, N. F. (2001) Analysis of telomerase processivity: Mechanistic similarity to HIV-1 reverse transcriptase and role in telomere maintenance, Mol. Cell 7, 1201-11.
    • (2001) Mol. Cell , vol.7 , pp. 1201-1211
    • Peng, Y.1    Mian, I.S.2    Lue, N.F.3
  • 11
    • 0025743438 scopus 로고
    • Telomerase primer specificity and chromosome healing
    • Harrington, L. A., and Greider, C. W. (1991) Telomerase primer specificity and chromosome healing, Nature 353, 451-4.
    • (1991) Nature , vol.353 , pp. 451-454
    • Harrington, L.A.1    Greider, C.W.2
  • 12
    • 0032834328 scopus 로고    scopus 로고
    • Ciliate telomerase biochemistry
    • Collins, K. (1999) Ciliate telomerase biochemistry, Annu. Rev. Biochem. 68, 187-218.
    • (1999) Annu. Rev. Biochem. , vol.68 , pp. 187-218
    • Collins, K.1
  • 13
    • 0035723994 scopus 로고    scopus 로고
    • Functional multimerization of the human telomerase reverse transcriptase
    • Beattie, T. L., Zhou, W., Robinson, M. O., and Harrington, L. (2001) Functional multimerization of the human telomerase reverse transcriptase, Mol. Cell. Biol. 21, 6151-60.
    • (2001) Mol. Cell. Biol. , vol.21 , pp. 6151-6160
    • Beattie, T.L.1    Zhou, W.2    Robinson, M.O.3    Harrington, L.4
  • 14
    • 0035796403 scopus 로고    scopus 로고
    • Human telomerase contains two cooperating telomerase RNA molecules
    • Wenz, C., Enenkel, B., Amacker, M., Kelleher, C., Damm, K., and Lingner, J. (2001) Human telomerase contains two cooperating telomerase RNA molecules, EMBO J. 20, 3526-34.
    • (2001) EMBO J. , vol.20 , pp. 3526-3534
    • Wenz, C.1    Enenkel, B.2    Amacker, M.3    Kelleher, C.4    Damm, K.5    Lingner, J.6
  • 15
    • 1942453903 scopus 로고    scopus 로고
    • Functional organization of repeat addition processivity and DNA synthesis determinants in the human telomerase multimer
    • Moriarty, T. J., Marie-Egyptienne, D. T., and Autexier, C. (2004) Functional organization of repeat addition processivity and DNA synthesis determinants in the human telomerase multimer, Mol. Cell. Biol. 24, 3720-33.
    • (2004) Mol. Cell. Biol. , vol.24 , pp. 3720-3733
    • Moriarty, T.J.1    Marie-Egyptienne, D.T.2    Autexier, C.3
  • 16
    • 0344875514 scopus 로고    scopus 로고
    • Tetrahymena telomerase is active as a monomer
    • Bryan, T. M., Goodrich, K. J., and Cech, T. R. (2003) Tetrahymena telomerase is active as a monomer, Mol. Biol. Cell 14, 4794-804.
    • (2003) Mol. Biol. Cell , vol.14 , pp. 4794-4804
    • Bryan, T.M.1    Goodrich, K.J.2    Cech, T.R.3
  • 17
    • 0030781067 scopus 로고    scopus 로고
    • Functionally interacting telomerase RNAs in the yeast telomerase complex
    • Prescott, J., and Blackburn, E. H. (1997) Functionally interacting telomerase RNAs in the yeast telomerase complex, Genes Dev. 11, 2790-800.
    • (1997) Genes Dev. , vol.11 , pp. 2790-2800
    • Prescott, J.1    Blackburn, E.H.2
  • 18
    • 0029763191 scopus 로고    scopus 로고
    • Purification of telomerase from Euplotes aediculatus: Requirement of a primer 3′ overhang
    • Lingner, J., and Cech, T. R. (1996) Purification of telomerase from Euplotes aediculatus: Requirement of a primer 3′ overhang, Proc. Natl. Acad. Sci. U.S.A. 93, 10712-7.
    • (1996) Proc. Natl. Acad. Sci. U.S.A. , vol.93 , pp. 10712-10717
    • Lingner, J.1    Cech, T.R.2
  • 19
    • 0037614891 scopus 로고    scopus 로고
    • The Euplotes la motif protein p43 has properties of a telomerase-specific subunit
    • Aigner, S., Postberg, J., Lipps, H. J., and Cech, T. R. (2003) The Euplotes La motif protein p43 has properties of a telomerase-specific subunit, Biochemistry 42, 5736-47.
    • (2003) Biochemistry , vol.42 , pp. 5736-5747
    • Aigner, S.1    Postberg, J.2    Lipps, H.J.3    Cech, T.R.4
  • 20
    • 0037106337 scopus 로고    scopus 로고
    • Oligomerization of the telomerase reverse transcriptase from Euplotes crassus
    • Wang, L., Dean, S. R., and Shippen, D. E. (2002) Oligomerization of the telomerase reverse transcriptase from Euplotes crassus, Nucleic Acids Res. 30, 4032-9.
    • (2002) Nucleic Acids Res. , vol.30 , pp. 4032-4039
    • Wang, L.1    Dean, S.R.2    Shippen, D.E.3
  • 22
    • 0028231010 scopus 로고
    • The DNA of ciliated protozoa
    • Prescott, D. M. (1994) The DNA of ciliated protozoa, Microbiol. Rev. 58, 233-67.
    • (1994) Microbiol. Rev. , vol.58 , pp. 233-267
    • Prescott, D.M.1
  • 23
    • 0034669177 scopus 로고    scopus 로고
    • Euplotes telomerase contains an la motif protein produced by apparent translational frameshifting
    • Aigner, S., Lingner, J., Goodrich, K. J., Grosshans, C. A., Shevchenko, A., Mann, M., and Cech, T. R. (2000) Euplotes telomerase contains an La motif protein produced by apparent translational frameshifting, EMBO J. 19, 6230-9.
    • (2000) EMBO J. , vol.19 , pp. 6230-6239
    • Aigner, S.1    Lingner, J.2    Goodrich, K.J.3    Grosshans, C.A.4    Shevchenko, A.5    Mann, M.6    Cech, T.R.7
  • 24
    • 0028106199 scopus 로고
    • Telomerase RNAs of different ciliates have a common secondary structure and a permuted template
    • Lingner, J., Hendrick, L. L., and Cech, T. R. (1994) Telomerase RNAs of different ciliates have a common secondary structure and a permuted template, Genes Dev. 8, 1984-98.
    • (1994) Genes Dev. , vol.8 , pp. 1984-1998
    • Lingner, J.1    Hendrick, L.L.2    Cech, T.R.3
  • 25
    • 0018872413 scopus 로고
    • Gene-sized DNA molecules of the macronuclei in three species of hypotrichs: Size distributions and absence of nicks. DNA of ciliated protozoa. VIII
    • Swanton, M. T., Heumann, J. M., and Prescott, D. M. (1980) Gene-sized DNA molecules of the macronuclei in three species of hypotrichs: Size distributions and absence of nicks. DNA of ciliated protozoa. VIII, Chromosoma 77, 217-27.
    • (1980) Chromosoma , vol.77 , pp. 217-227
    • Swanton, M.T.1    Heumann, J.M.2    Prescott, D.M.3
  • 26
    • 0035476710 scopus 로고    scopus 로고
    • T-Loop assembly in vitro involves binding of TRF2 near the 3′ telomeric overhang
    • Stansel, R. M., de Lange, T., and Griffith, J. D. (2001) T-Loop assembly in vitro involves binding of TRF2 near the 3′ telomeric overhang, EMBO J. 20, 5532-40.
    • (2001) EMBO J. , vol.20 , pp. 5532-5540
    • Stansel, R.M.1    De Lange, T.2    Griffith, J.D.3
  • 27
    • 0037039377 scopus 로고    scopus 로고
    • Effects of nucleotide analogues on Euplotes aediculatus telomerase processivity: Evidence for product-assisted translocation
    • Jarstfer, M. B., and Cech, T. R. (2002) Effects of nucleotide analogues on Euplotes aediculatus telomerase processivity: Evidence for product-assisted translocation, Biochemistry 41, 151-61.
    • (2002) Biochemistry , vol.41 , pp. 151-161
    • Jarstfer, M.B.1    Cech, T.R.2
  • 28
    • 0017869441 scopus 로고
    • Electron microscope visualization of chromatin and other DNA-protein complexes
    • Griffith, J. D., and Christiansen, G. (1978) Electron microscope visualization of chromatin and other DNA-protein complexes, Annu. Rev. Biophys. Bioeng. 7, 19-35.
    • (1978) Annu. Rev. Biophys. Bioeng. , vol.7 , pp. 19-35
    • Griffith, J.D.1    Christiansen, G.2
  • 29
    • 0031026387 scopus 로고    scopus 로고
    • The anchor site of telomerase from Euplotes aediculatus revealed by photocross-linking to single- and double-stranded DNA primers
    • Hammond, P. W., Lively, T. N., and Cech, T. R. (1997) The anchor site of telomerase from Euplotes aediculatus revealed by photocross-linking to single- and double-stranded DNA primers, Mol. Cell. Biol. 17, 296-308.
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 296-308
    • Hammond, P.W.1    Lively, T.N.2    Cech, T.R.3
  • 30
    • 0030850982 scopus 로고    scopus 로고
    • dGTP-dependent processivity and possible template switching of euplotes telomerase
    • Hammond, P. W., and Cech, T. R. (1997) dGTP-dependent processivity and possible template switching of euplotes telomerase, Nucleic Acids Res. 25, 3698-704,
    • (1997) Nucleic Acids Res. , vol.25 , pp. 3698-3704
    • Hammond, P.W.1    Cech, T.R.2
  • 31
    • 0032515965 scopus 로고    scopus 로고
    • Euplotes telomerase: Evidence for limited base-pairing during primer elongation and dGTP as an effector of translocation
    • Hammond, P. W., and Cech, T. R. (1998) Euplotes telomerase: Evidence for limited base-pairing during primer elongation and dGTP as an effector of translocation, Biochemistry 37, 5162-72.
    • (1998) Biochemistry , vol.37 , pp. 5162-5172
    • Hammond, P.W.1    Cech, T.R.2
  • 32
    • 0032562649 scopus 로고    scopus 로고
    • TRF1 promotes parallel pairing of telomeric tracts in vitro
    • Griffith, J., Bianchi, A., and de Lange, T. (1998) TRF1 promotes parallel pairing of telomeric tracts in vitro, J. Mol. Biol. 278, 79-88.
    • (1998) J. Mol. Biol. , vol.278 , pp. 79-88
    • Griffith, J.1    Bianchi, A.2    De Lange, T.3
  • 34
    • 11144235139 scopus 로고    scopus 로고
    • Processive utilization of the human telomerase template: Lack of a requirement for template switching
    • Rivera, M. A., and Blackburn, E. H. (2004) Processive utilization of the human telomerase template: Lack of a requirement for template switching, J. Biol. Chem. 279, 53770-81.
    • (2004) J. Biol. Chem. , vol.279 , pp. 53770-53781
    • Rivera, M.A.1    Blackburn, E.H.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.