Genome sequence diversity and clues to the evolution of variola (smallpox) virus

Science

Volumn 313, Issue 5788, 2006, Pages 807-812

  Esposito, Joseph J ^a   Sammons, Scott A ^a   Frace, A Michael ^a   Osborne, John D ^a,e   Glsen Rasmussen, Melissa ^a   Zhang, Ming ^a,f   Govil, Dhwani ^a   Damon, Inger K ^b   Kline, Richard ^b   Laker, Miriam ^b,g   Li, Yu ^b   Smith, Geoffrey L ^c   Meyer, Hermann ^d   LeDuc, James W ^b   Wohlhueter, Robert M ^a  

^a NATIONAL CENTER FOR PREPAREDNESS DETECTION AND CONTROL OF INFECTIOUS DISEASES   (United States)

^b CENTERS FOR DISEASE CONTROL AND PREVENTION   (United States)

^c IMPERIAL COLLEGE LONDON   (United Kingdom)

^d BUNDESWEHR INSTITUTE OF MICROBIOLOGY   (Germany)

^e NORTHWESTERN UNIVERSITY   (United States)

^f UNIVERSITY OF GÖTTINGEN   (Germany)

^g NONE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DIAGNOSIS; DNA; GENES; VIRUSES;

PHYLOGENETIC CLUSTERING; THERAPEUTICS; VIRAL PROTEOME;

GENETIC ENGINEERING;

VIRUS DNA; VIRUS PROTEIN;

COMPARATIVE STUDY; DNA; EPIDEMIOLOGY; GENOMICS; PHYLOGENETICS; SMALLPOX; VIRUS;

ARTICLE; CLADISTICS; COMPARATIVE GENOMIC HYBRIDIZATION; DNA RECOMBINATION; DNA SEQUENCE; GENE SEQUENCE; GENETIC VARIABILITY; GEOGRAPHIC ORIGIN; MOLECULAR EVOLUTION; NONHUMAN; OPEN READING FRAME; PHYLOGENY; PRIORITY JOURNAL; SEQUENCE ANALYSIS; SMALLPOX VIRUS; VIRUS GENE; VIRUS GENOME; VIRUS ISOLATION; VIRUS VIRULENCE;

DISEASE OUTBREAKS; DNA, VIRAL; EVOLUTION, MOLECULAR; GENE DELETION; GENOME, VIRAL; GENOMICS; HUMANS; MOLECULAR SEQUENCE DATA; OPEN READING FRAMES; PHYLOGENY; PROTEOME; RECOMBINATION, GENETIC; SEQUENCE ANALYSIS, DNA; SMALLPOX; VARIATION (GENETICS); VARIOLA VIRUS; VIRAL PROTEINS; VIRULENCE;

VARIOLA VIRUS;

EID: 33747106195     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.1125134     Document Type: Article

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42. We thank J. L. Patton, M. Khristova, D. Carroll, S. Reeder, R. Morey, and R. Galloway for expert technical assistance; C. Chesley for grammatical advice; the Poxvirus Bioinformatics Resource Center (www.poxvirus.org and www.biovirus.org) for poxvirus orthologous clusters (POCs) and viral orthologous clusters (VOCs) source codes; J. Rozas for Dna5P source code; A. J. Gibbs, M. J, Gibbs, and J. S. Armstrong for SiScan; and K. R. Dumbell and F. Fenner for smallpox history information. D.G. is funded by Atlanta Research and Education Foundation, Decatur, GA. Sequence data are deposited under GenBank accession numbers AY313847, DQ437580-DQ437594, and DQ441416-DQ441448.