The evaluation of formulations for the preparation of pellets with high drug loading by extrusion/spheronization

Pharmaceutical Development and Technology

Volumn 11, Issue 3, 2006, Pages 263-274

  Podczeck, Fridrun ^a   Knight, Paul ^b  

^a UNIVERSITY OF SUNDERLAND   (United Kingdom)

^b UNIVERSITY OF LONDON   (United Kingdom)

Author keywords

Capillary rheometry; Drugs; Extrusion spheronization; Fluid mobility; Microcrystalline cellulose; Pellets

Indexed keywords

ASCORBIC ACID; BUFFER; IBUPROFEN; LACTOSE; MICROCRYSTALLINE CELLULOSE; WATER;

ANALYTIC METHOD; ANGLE OF CONVERGENCE; ARTICLE; CAPILLARY RHEOMETER; DIE ENTRY PRESSURE; DRUG FORMULATION; DRUG LOADING; DRUG MIXTURE; DRUG PELLET; DRUG SCREENING; DRUG SOLUBILITY; ELASTICITY; EXTENSIONAL FLOW; FLOW MEASUREMENT; FLUID FLOW; PARAMETER; PARTICLE SIZE; PELLET EXTRUSION; PHARMACEUTICAL ENGINEERING; PRESSURE; PRIORITY JOURNAL; SHEAR STRESS; SPHERONIZATION; WET MASS;

ASCORBIC ACID; BUFFERS; CELLULOSE; CHEMISTRY, PHARMACEUTICAL; DRUG IMPLANTS; EVALUATION STUDIES; HYDROGEN-ION CONCENTRATION; IBUPROFEN; LACTOSE; PARTICLE SIZE; POWDERS; RHEOLOGY; SOLUBILITY; TECHNOLOGY, PHARMACEUTICAL; WATER;

EID: 33747098187     PISSN: 10837450     EISSN: 10979867     Source Type: Journal    
DOI: 10.1080/10837450600767284     Document Type: Article

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